Javier-David Benitez-Fuentes
Javier-David Benitez-Fuentes
Molecular subtyping-guided precision therapy for ESCC: biomarker-driven strategies and clinical translation pathways [0.03%]
食管癌分子分型指导的精准治疗：生物标志物驱动策略与临床转化路径
Huifang Lv,Wanying Zhao,Sai-Qi Wang et al.
Huifang Lv et al.
Esophageal squamous cell carcinoma (ESCC) is a highly aggressive malignancy with significant geographical disparities, particularly high in East Asia. The prognosis for advanced patients remains poor, largely due to profound intertumoral an...
Nodule size significantly affects the diagnostic value of chinese thyroid imaging reporting and data system: a multi-center retrospective study [0.03%]
结节大小显著影响中国甲状腺影像报告和数据系统诊断价值的多中心回顾性研究
Hu Huang,Qi Gao,Hong-Jian Li et al.
Hu Huang et al.
Purpose: This study aimed to investigate the influence of thyroid nodule size on the diagnostic efficacy of the Chinese thyroid imaging reporting and data system (C-TIRADS). ...
The logarithmic phase as a therapeutic direction: evaluating pharmacological strategies against cancer progression [0.03%]
对数期作为治疗方向：评估针对癌症进展的药理策略
Sushanta Kumar Das,Saptarshi Dutta,Sabitri Pradhan et al.
Sushanta Kumar Das et al.
Cancer remains a significant medical crisis and health burden globally, with an estimated 20 million new cases and nearly 10 million deaths annually, as per GLOBOCAN 2022. The disease burden continues to grow due to an ageing population, ch...
Colorectal neoplasia-specific amino acid profiles and their diagnostic potential: a systematic review [0.03%]
结直肠肿瘤特异性氨基酸谱及其诊断潜力的系统评价
Roza C M Opperman,Sofie Bosch,Eduard A Struys et al.
Roza C M Opperman et al.
Background: Metabolomics offers novel insights into metabolic alterations in colorectal cancer (CRC), including changes in amino acid profiles. Several studies have reported differences between CRC patients and controls, ...
Construction and validation of a prognostic model for 1 year all-cause mortality risk in patients with colorectal cancer liver metastases after HIFU treatment [0.03%]
超声治疗后结直肠癌肝转移患者一年内全因死亡率预测模型的构建与验证
Fan Yang,Bo Li,Guohua Huang et al.
Fan Yang et al.
Purpose: Colorectal cancer liver metastases (CRLM) worsen the prognosis of patients. High-intensity focused ultrasound (HIFU) is a non-invasive treatment for CRLM, but reliable prognostic tools for HIFU patients are lacki...
Epigenetic insights and innovations for overcoming barriers in CAR-T cell therapy for cancer [0.03%]
表观遗传学见解和创新克服癌症CAR-T细胞治疗障碍
Viktoria B Poluektova,Svetlana N Zuevskaya,Yarmatov Suvon et al.
Viktoria B Poluektova et al.
Over the past several decades, chimeric antigen receptor (CAR)-T cell therapy has revolutionized cancer immunotherapy, particularly for hematological cancers. However, its effectiveness against solid tumors is often hindered by numerous bar...
Proteomic profiling of CD133 + and CD326 + (EpCAM) subpopulations in A549 cells: insights into pluripotency and tumor heterogeneity [0.03%]
A549细胞中CD133+和CD326+(EpCAM)亚群的蛋白质谱分析：多能性与肿瘤异质性的启示
Fatih Ömerli,Medine Doğan Sarıkaya,Mustafa Burak Acar et al.
Fatih Ömerli et al.
Objective: This study aimed to isolate different cancer cell populations and characterize their secretome profiles to better understand their functional roles in metastasis and tumor progression. For this purpose, we anal...
Comparison of plasma cytokine expression in adult haematological malignancy patients with bacterial and/or fungal infections [0.03%]
血液系统恶性肿瘤患者合并细菌和/或真菌感染的血浆细胞因子表达比较分析
Najihah Hussein,Gin Gin Gan,Rukumani Devi Velayuthan et al.
Najihah Hussein et al.
Background: Bacterial and fungal infections pose significant challenges in the management of patients with haematological malignancies (HM), substantially affecting the impact on clinical outcomes, including prolonged hos...
Reprogramming resistance in advanced lung cancer: epigenetic modulation to restore therapeutic vulnerability [0.03%]
晚期肺癌的重编程耐药性：表观遗传调控以恢复治疗敏感性
Fang He,Mostafa Hossam El Din Moawad,Mohamed A Alsaied et al.
Fang He et al.
Lung cancer is the most prevalent cancer and cause of death; most patients present themselves at an advanced stage and continuously acquire resistance to targeted agents, antibody-drug conjugates, chemotherapy, and immune checkpoint inhibit...