Interdisciplinary Spanish consensus on a watch-and-wait approach for rectal cancer [0.03%]
西班牙多学科共识：观察等待策略在直肠癌中的应用
Maria Jose Safont,Roberto García-Figueiras,Ovidio Hernando-Requejo et al.
Maria Jose Safont et al.
Watch-and-wait has emerged as a new strategy for the management of rectal cancer when a complete clinical response is achieved after neoadjuvant therapy. In an attempt to standardize this new clinical approach, initiated by the Spanish Coop...
Machine-learning-based classification of diffuse large B-cell lymphoma patients by a 7-mRNA signature enriched with immune infiltration and cell cycle [0.03%]
基于机器学习的弥漫性大B细胞淋巴瘤患者的分类方法：富含免疫浸润和细胞周期的7个mRNA标志物签名
Xujie Zhuang,Bo Liu,Junqi Long et al.
Xujie Zhuang et al.
Background: Diffuse large B-cell lymphoma (DLBCL) exhibits remarkable heterogeneity but still remains undiagnosed in identifying the subpopulation of DLBCL to predict the prognosis and guide clinical treatment. ...
Myelodysplastic syndromes mortality in Spain: a comprehensive age-period-cohort and joinpoint analysis [0.03%]
西班牙的骨髓增生异常综合征死亡率：全面的年龄-时期-队列和连接点分析
Reyes María Martín-Rojas,Lucía Cayuela,Francisco Martín-Domínguez et al.
Reyes María Martín-Rojas et al.
Objective: The present study aims to assess the mortality trends in myelodysplastic syndromes (MDS) in Spain from 1980 to 2021. Methods: ...
Recommendations for the management of yttrium-90 radioembolization in the treatment of patients with colorectal cancer liver metastases: a multidisciplinary review [0.03%]
钇-90放射性微球选择性内照射治疗转移性结直肠癌肝癌的专家共识声明：多学科回顾性研究
Encarna González-Flores,Natalia Zambudio,Pedro Pardo-Moreno et al.
Encarna González-Flores et al.
Purpose: Strategies for the treatment of liver metastases from colon cancer (lmCRC) are constantly evolving. Radioembolization with yttrium 90 (Y-90 TARE) has made significant advancements in treating liver tumors and is ...
Yiwen Zhang,Yueli Nie,Xiyu Liu et al.
Yiwen Zhang et al.
Tumor cells must resist the host's immune system while maintaining growth under harsh conditions of acidity and hypoxia, which indicates that tumors are more robust than normal tissue. Immunotherapeutic agents have little effect on solid tu...
Prognostic model of ER-positive, HER2-negative breast cancer predicted by clinically relevant indicators [0.03%]
由临床相关指标预测的雌激素受体阳性、人类表皮生长因子受体阴性乳腺癌预后模型
Xinming Song,Pintian Wang,Ruiling Feng et al.
Xinming Song et al.
Purpose: To study the clinicopathological variables connected with disease-free survival (DFS) as well as overall survival (OS) in patients who are ER-positive or HER2-negative and to propose nomograms for predicting indi...
Identification of immune-related signature with prognosis in children with stage 4 and 4S neuroblastoma [0.03%]
鉴定出儿童IV期和IVS期神经母细胞瘤免疫相关预后标志物
Lijian Cao,Qingqing Liu,Yue Ma et al.
Lijian Cao et al.
Objective: Spontaneous regression of tumors is an attractive phenomenon that most commonly occurs in stage 4S neuroblastoma (NB). However, the mechanism underlying this phenomenon remains unclear. ...
Effect of HER2-low expression on neoadjuvant efficacy in operable breast cancer [0.03%]
HER2低表达对可手术乳腺癌新辅助治疗疗效的影响分析
Xiaoli Yi,Shasha Hu,Meili Ma et al.
Xiaoli Yi et al.
Objective: To investigate the effects of HER2-low expression (HER2-low) and HER2-zero expression (HER2-0) on the pathological complete response (pCR) rate and survival of patients following neoadjuvant chemotherapy. ...
Comprehensive profiling of enhancer RNA in stage II/III colorectal cancer defines two prognostic subtypes with implications for immunotherapy [0.03%]
结肠直肠癌中的增强子RNA综合分析确定了两个预后亚型及其对免疫治疗的意义
Xiaoyun Bu,Shuang Liu,Zhiqing Zhang et al.
Xiaoyun Bu et al.
Background: Recently, enhancer RNAs (eRNAs) have garnered attention as pivotal biomarkers for the onset and progression of cancer. However, the landscape of eRNAs and the implications of eRNA-based molecular subtypes in s...
Early kinetics of C-reactive protein as prognosticator for survival in a real-world cohort of patients with metastatic renal cell cancer under first-line therapy with immune checkpoint inhibitors [0.03%]
在一线免疫检查点抑制剂治疗的转移性肾细胞癌患者中，C-反应蛋白早期动力学作为生存预测因子的作用：一项真实世界队列研究
Vayda Schüttke,Cathrin Kusiek,Susanne Fuessel et al.
Vayda Schüttke et al.
Purpose: This study investigated the prognostic potential of baseline C-reactive protein (CRP) levels and early CRP kinetics in a real-world cohort of patients with metastatic renal cell carcinoma (mRCC) under first-line ...