Circ-JA760602 promotes the apoptosis of hypoxia-induced cardiomyocytes by transcriptionally suppressing BCL2 [0.03%]
circ-JA760602通过转录抑制BCL2促进低氧诱导的心肌细胞凋亡
Chao Li,Jingwen Wang,Jun Feng et al.
Chao Li et al.
Acute myocardial infarction (AMI) is myocardial necrosis caused by the complete or partial obstruction of a coronary artery. Circular RNAs (circRNAs) have been proven as regulators in the progression of various human diseases, including AMI...
Single-cell transcriptomics defines Dot1L interacting partners and downstream target genes in the mouse molar dental pulp [0.03%]
单细胞转录组分析定义了小鼠磨牙牙髓中Dot1L互作蛋白及下游靶基因
Rosa Guzzo,Badam Enkhmandakh,Timothy Becker et al.
Rosa Guzzo et al.
Although histone methyltransferases are implicated in many key developmental processes, the contribution of individual chromatin modifiers in dental tissues is not well understood. Using single-cell RNA sequencing, we examined the expressio...
The involvement of hormone-sensitive lipase in all-trans retinoic acid induced cleft palate [0.03%]
全反式维甲酸诱导腭裂中甘油三酯脂肪酶的参与作用
K Zheng,Q N Ye
K Zheng
Abnormally high concentrations of all-trans retinoic acid (atRA) induce cleft palate, which is accompanied by abnormal migration and proliferation of mouse embryonic palatal mesenchyme (MEPM) cells. Hormone-sensitive lipase (HSL) is involve...
Regeneration and proliferation of cardiomyocytes and its microRNA regulatory mechanisms [0.03%]
心肌细胞的再生和增殖及其microRNA调控机制
Shu-Ning Guo,Jie-Han Li,Jing Li et al.
Shu-Ning Guo et al.
Myocardial regeneration is identified as a concept at histological level. The core content is to increase the number of cardiomyocytes (CMs), so as to maintain the steady state of CMs under pathological or physiological conditions and ensur...
Cyclooxygenase-2 plays a crucial role during myocardial patterning of developing chick [0.03%]
环氧化酶-2在发育中的鸡心肌模式形成中起着关键作用
Bhaval K Parmar,Urja R Verma,Juhi A Vaishnav et al.
Bhaval K Parmar et al.
Cyclooxygenase-2 (COX-2), a member of the Cyclooxygenase family, initiates the biosynthesis of prostanoids that regulates various cellular functions. Our pilot attempt revealed that the administration of etoricoxib, an inhibitor specific fo...
Intraflagellar transport 20 cilia-dependent and cilia-independent signaling pathways in cell development and tissue homeostasis [0.03%]
基于纤毛依赖和非依赖信号转导途径在细胞发育及组织稳态中的作用研究：IFT20为例
Fu-Chang Jin,Ming-Hui Zhou,Jing-Jing Chen et al.
Fu-Chang Jin et al.
Intraflagellar transport (IFT) is an essential condition for ciliogenesis. The primary cilia protrude like antennae and act as chemical or mechanical sensory organelles that coordinate specific receptor localization and signal transduction....
Exploring the sister cells of embryo sac: developmental and functional attributes [0.03%]
探索胚囊姐妹细胞的发育和功能属性
Inderdeep Kaur,Monika Koul
Inderdeep Kaur
Synergids are metabolically dynamic cells of the egg apparatus and represent an important component of the female gametophyte. Besides directing the growth of the pollen tube towards the micropylar end of the embryo sac, these ephemeral str...
Monica Alves Rodrigues-Da-Silva,Guilherme de Espindola da Silveira,Clarissa Reginato Taufer et al.
Monica Alves Rodrigues-Da-Silva et al.
It has long been held that the main difference between cranial and trunk neural crest (CNC and TNC, respectively) was the potential of CNC to originate mesenchymal cell types, especially skeletogenic. This is an age-old question that contin...
Correlation between CDK1 protein and CDK1 mRNA during oocyte maturation in mouse [0.03%]
小鼠卵母细胞成熟过程中CDK1蛋白与CDK1mRNA的相关性研究
Ya-Ting Sun,Ai-Zhen Zhu
Ya-Ting Sun
The aim of this study was to investigate the correlation between CDK1 protein and CDK1 mRNA during oocyte maturation in vivo in mouse. GV, GVBD, MI and MII oocytes were obtained from mice, respectively. Western blot validated that the CDK1 ...
Nikolas Zagris
Nikolas Zagris
Aristotle made important contributions to many fields-biology, physics, metaphysics, logic, ethics, rhetoric, psychology, aesthetics, poetry- that are now cultivated by specialized experts, but he never lost sight of the aim of unifying kno...