Development of the dorsal thalamus in a reptile: identification of subdivisions and their associated nuclei [0.03%]
关于爬行脑的研究:亚区及其相关核的鉴定发展背侧丘脑
Michael B Pritz
Michael B Pritz
How the dorsal thalamus of amniotes (reptiles, birds, and mammals) is organized remains an important but incompletely answered question. Identification of meaningful subdivisions would greatly aid in its understanding. Because the dorsal th...
Innervation of the masseter requires Mllt11 (Af1q/Tcf7c) function during trigeminal ganglion development [0.03%]
Mllt11(Af1q/Tcf7c)在三叉神经节发育过程中对于咬肌的神经支配是必需的
Nicholas W Zinck,Danielle Stanton-Turcotte,Emily A Witt et al.
Nicholas W Zinck et al.
The development of cranial nerves, including the trigeminal nerve, and the formation of neuromuscular junctions (NMJs) are crucial processes for craniofacial motor function. Mllt11/Af1q/Tcf7c (hereafter Mllt11), a novel type of cytoskeletal...
Characterization of somatic testicular cells during human development: fetal, peripubertal, adolescent and adult human testis from healthy and infertility related disease [0.03%]
人一生中体细胞性腺细胞的特征:来自健康和与不孕症相关疾病中的胎儿、青春期前、青少年及成人睾丸
Myriam Martin-Inaraja,Lara Herrera,Silvia Santos et al.
Myriam Martin-Inaraja et al.
The transcription factor GATA4 is found in Sertoli and Leydig cells, whereas SOX9 is exclusive to Sertoli cells, being both factors essential for the normal development of murine and human fetal testis. In turn, the steroidogenic acute regu...
Miroo Hong,Joung-Woo Hong
Miroo Hong
The enhancer threshold is defined as the minimum concentration of transcription factors (TFs) required to elicit an enhancer response in a given time and space. Here, evidence is presented that the enhancer threshold is relative to promoter...
RNA and proteins extracted from the regenerating tail of lizards determine inhibition of cancer cell proliferation [0.03%]
壁虎再生尾巴中的RNA和蛋白质具有抑制癌细胞增殖的作用
Nicola Greco,Maurizio Onisto,Lorenzo Alibardi
Nicola Greco
Recent studies suggest that tail regeneration in lizards begins with a tumor-like stage usually termed regenerative blastema. Oncogenes and tumor suppressors are activated in blastema cells, resulting in a balanced cell proliferation that d...
Tension-induced enhancement of SIX1 expression during preplacodal ectoderm differentiation from human induced pluripotent stem cells [0.03%]
张力诱导的人诱导多能干细胞向预皮带外胚层分化过程中的SIX1表达增强现象
Seungtae Kim,Ayumi Horikawa,Takayoshi Yamamoto et al.
Seungtae Kim et al.
Based on observations of in vivo morphogenesis, differentiation is expected to be regulated by mechanical cues. However, the detail mechanisms remain largely unknown. A previous study using human pluripotent stem cells (hPSCs) demonstrated ...
TLR7 expression patterns in mouse eye development and adult ocular tissues [0.03%]
小鼠眼睛发育及成年眼部组织中TLR7的表达模式
Marco Rasile,Michele Sommariva,Elena Menegola et al.
Marco Rasile et al.
Toll-Like Receptor 7 (TLR7) is recognized for its role in immune responses, particularly in detecting viral RNA. However, emerging evidence suggests that TLR7 may also contribute to ocular development. In this study, we assessed the express...
Melastatin family Transient Receptor Potential channels support spermatogenesis in planarian flatworms [0.03%]
瞬时受体电位通道梅拉司汀族支持平面虫的精子发生
Haley Nicole Curry,Roger Huynh,Labib Rouhana
Haley Nicole Curry
The Transient Receptor Potential superfamily of proteins (TRPs) form cation channels that are abundant in animal sensory systems. Amongst TRPs, the Melastatin-related family (TRPMs) is composed of members that respond to temperature, pH, se...
Three Decades of the Spanish Society for Developmental Biology (SEBD): Insights and Emerging Perspectives from the 18th Spanish Society for Developmental Biology Meeting (SEBD 2024) [0.03%]
西班牙发育生物学会(SEBD)三十年:第18届西班牙发育生物学会会议(SEBD 2024)的洞见与新兴观点
Eloisa Herrera,Sandra Acosta,María Almuedo et al.
Eloisa Herrera et al.
The Spanish Society for Developmental Biology (SEBD) organized its 18th meeting in October 2024 (hereafter SEBD2024), coinciding with the society's 30th anniversary and serving as the stage for its celebrations. This article provides an ove...
Inhibition of COX2 impairs angiogenesis and causes vascular defects in developing zebrafish embryos [0.03%]
COX2抑制损害斑马鱼胚胎血管生成并致血管缺陷
Lakshmi Pillai,Vishakha Nesari,Dhanush Danes et al.
Lakshmi Pillai et al.
This study investigated the role of cyclooxygenase-2 (COX2) in angiogenesis during zebrafish embryogenesis by inhibiting COX2 activity with etoricoxib. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis confirmed the success...