Evaluation of changes of apelin and apelin receptor (APJ) expression in cervix-uterus and placental axis in an LPS-induced preterm labor model [0.03%]
LPS诱导的早产模型宫颈-子宫及胎盘轴中aplin和aplin受体(APJ)表达变化的研究
Sema Avci,Ezgi Golal,Nuray Acar
Sema Avci
Although preterm birth is among the preventable causes of maternal and infant death, its mechanism has not yet been clarified. When evaluated in terms of the results, the psycho-social burden of mother-infant losses and the costs of rehabil...
Insights into the role of the Wnt signaling pathway in the regeneration of animal model systems [0.03%]
模式动物系统中Wnt信号通路在再生作用中的研究进展
Katarzyna S Walczyńska,Ling Zhu,Yujun Liang
Katarzyna S Walczyńska
Regeneration enables the regrowth and restoration of missing body parts. It is a common phenomenon among animals. However, only some species exhibit remarkable regeneration capabilities and can regenerate organs such as limbs, lenses or hea...
Valproic acid effects on human adipose-derived stem cell differentiation into oligodendrocytes and improved remyelination in a mouse model of Multiple Sclerosis [0.03%]
富马酸钠对人类脂肪来源干细胞向少突胶质细胞分化及改善小鼠多发性硬化模型再髓鞘化的影响
Sahar Ghosouri,Mohammad Bakhtiari,Soleimani Mitra et al.
Sahar Ghosouri et al.
Valproic acid (VPA), a neuroprotective agent and inhibitor of GSK3-β, along with human Adipose-Derived Stem Cells (hADSCs) have been proposed to be potential therapeutic agents for neurodegenerative disorders. In the present study, we have...
Polarized contact behavior in directionally migrating Xenopus gastrula mesendoderm [0.03%]
极化接触行为在分化迁徙的非洲爪蟾原肠胚中肠端细胞中的作用
Martina Nagel,Rudolf Winklbauer
Martina Nagel
The control of cell-cell adhesion and detachment is essential for collective migration and cell rearrangement. Here, we have used the contact behavior of Xenopus gastrula mesoderm explants migrating directionally on ectoderm conditioned sub...
Characterization of the developing axolotl nasal cavity supports multiple evolution of the vertebrate choana [0.03%]
虎纹火蜥蜴鼻腔的特征表明脊椎动物choana的多次进化具有偶然性
Batoul Chami,Bella Bates,Luke Shaheen et al.
Batoul Chami et al.
All tetrapods (mammals, birds, reptiles, and amphibians) share the ability to breathe with their mouths closed due to the formation of choanae, which are openings that allow communication between the nasal and oral cavities. In most fishes,...
Conditions for transplantation of primordial germ cells in the yellowtail tetra, Astyanax altiparanae [0.03%]
黄尾四目鱼Astyanax altiparanae原始生殖细胞移植的条件
Geovanna Carla Zacheo Coelho,Gabriella Braga Carvalho,Paulo Sergio Monzani et al.
Geovanna Carla Zacheo Coelho et al.
Biotechniques, including surrogate propagation derived from primordial germ cell (PGC) transplantation, are valuable tools for the reconstitution of endangered fish species. Although promising, there are no previous studies reporting such a...
Importance of the filamin A-Sav1 interaction in organ size control: evidence from transgenic mice [0.03%]
互作在器官大小调控中的作用:转基因小鼠证据
Huaguan Zhang,Ziwei Yang,Fumihiko Nakamura
Huaguan Zhang
The nucleocytoplasmic translocation of yes-associated protein 1 (YAP1) controls the growth of animal tissues and organs. YAP1 binds to transcription factors in the nucleus to activate the transcription of proliferation and anti-apoptotic ge...
The Dyslexia-associated gene KIAA0319L is involved in neuronal migration in the developing chick visual system [0.03%]
与阅读障碍相关的基因KIAA0319L参与发育中鸡视觉系统神经元迁移
Jason Charish,Hidekiyo Harada,Xiaoyan Chen et al.
Jason Charish et al.
The gene KIAA0319-Like (KIAA0319L) is thought to confer susceptibility for developmental dyslexia. Dyslexia may be caused by alterations in neuronal migration, and in utero knockdown of KIAA0319L in rats indicated migration errors. However,...
DNA methyltransferase (Dnmt) silencing causes increased Cdx2 and Nanog levels in surviving embryos [0.03%]
DNA甲基转移酶(Dnmt)的沉默导致幸存胚胎中Cdx2和Nanog水平升高
Fatma Uysal,Gozde Sukur,Nazlican Bozdemir et al.
Fatma Uysal et al.
Epigenetic mechanisms are one of the essential regulators of gene expression which do not involve altering the primary nucleotide sequence. DNA methylation is considered among the most prominent epigenetic mechanisms in controlling the func...
Single-cell transcriptome profiling reveals distinct expression patterns among genes in the mouse incisor dental pulp [0.03%]
单细胞转录组分析揭示了小鼠前牙牙髓中基因的不同表达模式
Badam Enkhmandakh,Dashzeveg Bayarsaihan
Badam Enkhmandakh
SOX transcription factors play key roles in cell differentiation and cell fate determination during development. Using single-cell RNA-sequencing data, we examined the expression profiles of Sox genes in the mouse incisor dental pulp. Our a...