Conditions for transplantation of primordial germ cells in the yellowtail tetra, Astyanax altiparanae [0.03%]
黄尾四目鱼Astyanax altiparanae原始生殖细胞移植的条件
Geovanna Carla Zacheo Coelho,Gabriella Braga Carvalho,Paulo Sergio Monzani et al.
Geovanna Carla Zacheo Coelho et al.
Biotechniques, including surrogate propagation derived from primordial germ cell (PGC) transplantation, are valuable tools for the reconstitution of endangered fish species. Although promising, there are no previous studies reporting such a...
Importance of the filamin A-Sav1 interaction in organ size control: evidence from transgenic mice [0.03%]
互作在器官大小调控中的作用：转基因小鼠证据
Huaguan Zhang,Ziwei Yang,Fumihiko Nakamura
Huaguan Zhang
The nucleocytoplasmic translocation of yes-associated protein 1 (YAP1) controls the growth of animal tissues and organs. YAP1 binds to transcription factors in the nucleus to activate the transcription of proliferation and anti-apoptotic ge...
The Dyslexia-associated gene KIAA0319L is involved in neuronal migration in the developing chick visual system [0.03%]
与阅读障碍相关的基因KIAA0319L参与发育中鸡视觉系统神经元迁移
Jason Charish,Hidekiyo Harada,Xiaoyan Chen et al.
Jason Charish et al.
The gene KIAA0319-Like (KIAA0319L) is thought to confer susceptibility for developmental dyslexia. Dyslexia may be caused by alterations in neuronal migration, and in utero knockdown of KIAA0319L in rats indicated migration errors. However,...
DNA methyltransferase (Dnmt) silencing causes increased Cdx2 and Nanog levels in surviving embryos [0.03%]
DNA甲基转移酶（Dnmt）的沉默导致幸存胚胎中Cdx2和Nanog水平升高
Fatma Uysal,Gozde Sukur,Nazlican Bozdemir et al.
Fatma Uysal et al.
Epigenetic mechanisms are one of the essential regulators of gene expression which do not involve altering the primary nucleotide sequence. DNA methylation is considered among the most prominent epigenetic mechanisms in controlling the func...
Single-cell transcriptome profiling reveals distinct expression patterns among genes in the mouse incisor dental pulp [0.03%]
单细胞转录组分析揭示了小鼠前牙牙髓中基因的不同表达模式
Badam Enkhmandakh,Dashzeveg Bayarsaihan
Badam Enkhmandakh
SOX transcription factors play key roles in cell differentiation and cell fate determination during development. Using single-cell RNA-sequencing data, we examined the expression profiles of Sox genes in the mouse incisor dental pulp. Our a...
Circ-JA760602 promotes the apoptosis of hypoxia-induced cardiomyocytes by transcriptionally suppressing BCL2 [0.03%]
circ-JA760602通过转录抑制BCL2促进低氧诱导的心肌细胞凋亡
Chao Li,Jingwen Wang,Jun Feng et al.
Chao Li et al.
Acute myocardial infarction (AMI) is myocardial necrosis caused by the complete or partial obstruction of a coronary artery. Circular RNAs (circRNAs) have been proven as regulators in the progression of various human diseases, including AMI...
Single-cell transcriptomics defines Dot1L interacting partners and downstream target genes in the mouse molar dental pulp [0.03%]
单细胞转录组分析定义了小鼠磨牙牙髓中Dot1L互作蛋白及下游靶基因
Rosa Guzzo,Badam Enkhmandakh,Timothy Becker et al.
Rosa Guzzo et al.
Although histone methyltransferases are implicated in many key developmental processes, the contribution of individual chromatin modifiers in dental tissues is not well understood. Using single-cell RNA sequencing, we examined the expressio...
The involvement of hormone-sensitive lipase in all-trans retinoic acid induced cleft palate [0.03%]
全反式维甲酸诱导腭裂中甘油三酯脂肪酶的参与作用
K Zheng,Q N Ye
K Zheng
Abnormally high concentrations of all-trans retinoic acid (atRA) induce cleft palate, which is accompanied by abnormal migration and proliferation of mouse embryonic palatal mesenchyme (MEPM) cells. Hormone-sensitive lipase (HSL) is involve...
Regeneration and proliferation of cardiomyocytes and its microRNA regulatory mechanisms [0.03%]
心肌细胞的再生和增殖及其microRNA调控机制
Shu-Ning Guo,Jie-Han Li,Jing Li et al.
Shu-Ning Guo et al.
Myocardial regeneration is identified as a concept at histological level. The core content is to increase the number of cardiomyocytes (CMs), so as to maintain the steady state of CMs under pathological or physiological conditions and ensur...
Cyclooxygenase-2 plays a crucial role during myocardial patterning of developing chick [0.03%]
环氧化酶-2在发育中的鸡心肌模式形成中起着关键作用
Bhaval K Parmar,Urja R Verma,Juhi A Vaishnav et al.
Bhaval K Parmar et al.
Cyclooxygenase-2 (COX-2), a member of the Cyclooxygenase family, initiates the biosynthesis of prostanoids that regulates various cellular functions. Our pilot attempt revealed that the administration of etoricoxib, an inhibitor specific fo...