Genetic targeting of lymphatic endothelial cells in mice: current strategies and future perspectives [0.03%]
小鼠淋巴内皮细胞的基因靶向：当前策略与未来展望
Hans Schoofs,Taija Mäkinen
Hans Schoofs
Lymphatic vessels within different organs have diverse developmental origins, depend on different growth factor signaling pathways for their development and maintenance, and display notable tissue-specific adaptations that contribute to the...
Kaia Achim
Kaia Achim
Understanding the structure and function of cells is central to cell biology and physiology. The ability to control cell function may benefit biomedicine, such as cell-replacement therapy or regeneration. If structure defines function and c...
Davide Martini,Chiara De Cesari,Matteo Digregorio et al.
Davide Martini et al.
The tRNA-histidine guanylyltransferase 1-like (THG1L), also known as induced in high glucose-1 (IHG-1), encodes for an essential mitochondria-associated protein highly conserved throughout evolution, that catalyses the 3'-5' addition of a g...
Mojtaba Esmaeli,Mahdi Barazesh,Zeinab Karimi et al.
Mojtaba Esmaeli et al.
During embryonic development, the vertebrate embryonic epiblast is divided into two parts including neural and superficial ectoderm. The neural plate border (NPB) is a narrow transitional area which locates between these parts and contains ...
Coenocystic oogenesis - modification of or deviation from the germ cell cyst paradigm? [0.03%]
合胞体卵生成：对生殖细胞合胞体范式的修改还是偏差？
Malgorzata Kloc
Malgorzata Kloc
Invertebrate and vertebrate species have many unusual cellular structures, such as long- or short-lived cell-in-cell structures and coenocytes. Coenocytes (often incorrectly described as syncytia) are multinuclear cells derived, unlike sync...
TBC1D24 is likely to regulate vesicle trafficking in glia-like non-sensory epithelial cells of the cochlea [0.03%]
TBC1D24很可能是通过调节顶襄膜囊泡运输在耳蜗支持细胞中的作用来发挥作用
Jean Defourny
Jean Defourny
Mutations in the gene encoding Tre2/Bub2/Cdc16 (TBC)1 domain family member 24 (TBC1D24) protein are associated with a variety of neurological disorders, ranging from non-syndromic hearing loss to drug-resistant lethal epileptic encephalopat...
Enhancer-promoter communication in Drosophila developmental gene transcription [0.03%]
果蝇发育基因转录中的增强子-启动子通讯
George Hunt,Mattias Mannervik
George Hunt
Enhancers play an essential role in gene regulation by receiving cues from transcription factors and relaying these signals to modulate transcription from target promoters. Enhancer-promoter communications occur across large linear distance...
TGF-β signaling molecules in Hydra: role of BMP and BMP inhibitors during pattern formation [0.03%]
水母中的TGF-β信号分子：BMP和BMP抑制因子在模式形成过程中的作用
Lakshmi-Surekha Krishnapati,Surendra Ghaskadbi
Lakshmi-Surekha Krishnapati
Understanding the evolution of body plans has been one of the major areas of investigation in developmental and evolutionary biology. Cnidaria, the sister group to bilaterians, provides an opportunity to elucidate the origin and evolution o...
Wnt target gene Ascl4 is dispensable for skin appendage development [0.03%]
Wnt靶基因Ascl4在附属皮肤器官发生过程中可有可无
Verdiana Papagno,Ana-Marija Sulic,Jyoti P Satta et al.
Verdiana Papagno et al.
The development of skin appendages, including hair follicles, teeth and mammary glands is initiated through the formation of the placode, a local thickening of the epithelium. The Wnt/β-catenin signaling cascade is an evolutionary conserve...
Sonja Nykänen,Sanna Vuoristo
Sonja Nykänen
During the initial days of development, the embryo gradually shifts from reliance on maternally provided RNAs and proteins to regulation of its own development. This transition is marked by embryonic genome activation (EGA). While the facto...