TLR7 expression patterns in mouse eye development and adult ocular tissues [0.03%]
小鼠眼睛发育及成年眼部组织中TLR7的表达模式
Marco Rasile,Michele Sommariva,Elena Menegola et al.
Marco Rasile et al.
Toll-Like Receptor 7 (TLR7) is recognized for its role in immune responses, particularly in detecting viral RNA. However, emerging evidence suggests that TLR7 may also contribute to ocular development. In this study, we assessed the express...
Melastatin family Transient Receptor Potential channels support spermatogenesis in planarian flatworms [0.03%]
瞬时受体电位通道梅拉司汀族支持平面虫的精子发生
Haley Nicole Curry,Roger Huynh,Labib Rouhana
Haley Nicole Curry
The Transient Receptor Potential superfamily of proteins (TRPs) form cation channels that are abundant in animal sensory systems. Amongst TRPs, the Melastatin-related family (TRPMs) is composed of members that respond to temperature, pH, se...
Three Decades of the Spanish Society for Developmental Biology (SEBD): Insights and Emerging Perspectives from the 18th Spanish Society for Developmental Biology Meeting (SEBD 2024) [0.03%]
西班牙发育生物学会(SEBD)三十年：第18届西班牙发育生物学会会议(SEBD 2024)的洞见与新兴观点
Eloisa Herrera,Sandra Acosta,María Almuedo et al.
Eloisa Herrera et al.
The Spanish Society for Developmental Biology (SEBD) organized its 18th meeting in October 2024 (hereafter SEBD2024), coinciding with the society's 30th anniversary and serving as the stage for its celebrations. This article provides an ove...
Inhibition of COX2 impairs angiogenesis and causes vascular defects in developing zebrafish embryos [0.03%]
COX2抑制损害斑马鱼胚胎血管生成并致血管缺陷
Lakshmi Pillai,Vishakha Nesari,Dhanush Danes et al.
Lakshmi Pillai et al.
This study investigated the role of cyclooxygenase-2 (COX2) in angiogenesis during zebrafish embryogenesis by inhibiting COX2 activity with etoricoxib. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis confirmed the success...
Unraveling hepatic consequences of intrauterine growth restriction and catch-up growth: insights from histological, biochemical and metabolomic analysis in rats [0.03%]
从组织学、生化和代谢组分析中探讨宫内生长受限及赶超生长的肝脏后果：大鼠实验研究
Mukaddes Esrefoğlu,Sahabettin Selek,Fatmanur Koktasoglu et al.
Mukaddes Esrefoğlu et al.
Intrauterine growth restriction (IUGR) is increasingly recognized as a significant risk factor for metabolic disorders in adulthood. Employing a multi-faceted approach encompassing histopathological, immunohistochemical, biochemical, Wester...
Fgf8 gene regulatory network and the isthmic organizer: an evolutionary perspective [0.03%]
Fgf8 基因调控网络与间脑后部组织中心：进化论的观点
Rajeev Chandel,Andreas Hörnblad
Rajeev Chandel
The midbrain-hindbrain boundary (MHB), also known as the isthmic organizer (IsO), plays a critical role in the developmental patterning of the posterior midbrain and anterior hindbrain. Understanding the wiring of this organizer's deeply co...
The Spemann-Mangold organiser and the dissemination of its discovery in interwar Finland [0.03%]
斯佩曼-芒戈尔德组织者及其在两次世界大战之间芬兰的传播发现
Jakke Neiro
Jakke Neiro
A century has passed since the publication of the discovery of the Spemann-Mangold organiser, most visibly celebrated by the Festschrift Spemann and Mangold centennial special issue in Cells & Development and the conference Self-Organizatio...
Seppo Vainio,Satu Kuure
Seppo Vainio
Ccer1 is a spermatid-specific gene required for spermatogenesis and male fertility [0.03%]
CCER1是精子特异性基因，对于雄性生育和精子发生至关重要
Bianca Sammer,Philomena Schmid,Haruhiko Miyata et al.
Bianca Sammer et al.
Male infertility is a multifactorial condition for which the underlying causes frequently remain undefined. Genetic factors have long been associated with male fertility. However, many of them are poorly or not at all characterized and thei...
Fibroblast Growth Factor 8 enhances the chondrogenesis of trunk neural crest cells: a possible gene regulatory network [0.03%]
成纤维细胞生长因子8促进躯干神经嵴细胞软骨发生：一个可能的基因调控网络
Raphaella Josino,Saloe Bispo,Bernardo Bonilauri et al.
Raphaella Josino et al.
The neural crest (NC) is an embryonic cell population with high migratory capacity. It contributes to forming several organs and tissues, such as the craniofacial skeleton and the peripheral nervous system of vertebrates. Both pre-migratory...