Winfried H Krueger,Lindsey C Swanson,Borko Tanasijevic et al.
Winfried H Krueger et al.
Pluripotent cells of the blastocyst inner cell mass (ICM) and their in vitro derivatives, embryonic stem (ES) cells, contain genomes in an epigenetic state that are poised for subsequent differentiation. Their chromatin is hyperdynamic in n...
What scientists would like to tell you about reprogramming (if only they knew!). Preface [0.03%]
科学家想对重编程告诉你什么（如果他们知道的话！）前言
Michele Boiani,José B Cibelli
Michele Boiani
Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos [0.03%]
Sox17依赖的基因表达及Sox17缺乏型小鼠胚胎早期心脏和肠道的发生发育
Sabine Pfister,Vanessa J Jones,Melinda Power et al.
Sabine Pfister et al.
Sox17 is a transcription factor that is required for maintenance of the definitive endoderm in mouse embryos. By expression profiling of wild-type and mutant embryos and Sox17-overexpressing hepatoma cells, we identified genes with Sox17-de...
Reprogramming cell fate to pluripotency: the decision-making signalling pathways [0.03%]
重编细胞命运至多能性：决定通路信号转导
Daniela Sanges,Maria-Pia Cosma
Daniela Sanges
Pluripotency can be defined as the ability of individual cells to initiate all of the lineages of the mature organism in response to signals from the environment. It has long been assumed that during development, pluripotency is progressive...
Porcine induced pluripotent stem cells analogous to naïve and primed embryonic stem cells of the mouse [0.03%]
类似小鼠多能干细胞的猪细胞诱导多功能干细胞
Bhanu Prakash V L Telugu,Toshihiko Ezashi,R Michael Roberts
Bhanu Prakash V L Telugu
Authentic or naïve embryonic stem cells (ESC) have probably never been derived from the inner cell mass (ICM) of pig blastocysts, despite over 25 years of effort. Recently, several groups, including ours, have reported induced pluripotent ...
Growth factor-defined culture medium for human mesenchymal stem cells [0.03%]
人 mesenchymal 干细胞的生长因子定义培养基
Sumiyo Mimura,Naohiro Kimura,Mitsuhi Hirata et al.
Sumiyo Mimura et al.
Human bone marrow-derived mesenchymal stem cells (hMSCs) are potential cellular sources of therapeutic stem cells as they have the ability to proliferate and differentiate into a wide array of mesenchymal cell types such as osteoblasts, cho...
Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells [0.03%]
人类胚胎干细胞和诱导多能干细胞在体外和体内的分化过程中线粒体生物合成及生物能量代谢的调节机制研究
Alessandro Prigione,James Adjaye
Alessandro Prigione
Reprogramming somatic cells to induced pluripotent stem (iPS) cells transforms differentiated cells to an embryonic stem (ES) cell-like state characterized by the acquisition of pluripotency and self-renewal capabilities. We recently demons...
Regulation of programmed cell death during neural induction in the chick embryo [0.03%]
鸡胚神经诱导过程中程序性细胞死亡的调节
Anna Gibson,Neil Robinson,Andrea Streit et al.
Anna Gibson et al.
To study early responses to neural inducing signals from the organizer (Hensen's node), a differential screen was performed in primitive streak stage chick embryos, comparing cells that had or had not been exposed to a node graft for 5 hour...
Comprehensive analysis of fibroblast growth factor receptor expression patterns during chick forelimb development [0.03%]
鸡前肢发育过程中成纤维细胞生长因子受体表达模式的全面分析
Caroline J Sheeba,Raquel P Andrade,Delphine Duprez et al.
Caroline J Sheeba et al.
Specific interactions between fibroblast growth factors (Fgf1-22) and their tyrosine kinase receptors (FgfR1-4) activate different signalling pathways that are responsible for the biological processes in which Fgf signalling is implicated d...
Expression pattern of iodotyrosine dehalogenase 1 (DEHAL1) during chick ontogeny [0.03%]
碘酪氨酸脱卤酶1(DEHAL1)在鸡胚发育过程中的表达模式研究
Anupama A Mathi,Tekchand C Gaupale,Corinne Dupuy et al.
Anupama A Mathi et al.
The iodotyrosine dehalogenase1 (DEHAL1) enzyme is a transmembrane protein that belongs to the nitroreductase family and shows a highly conserved N-terminal domain. DEHAL1 is present in the liver, kidney and thyroid of mammals. DEHAL1 is kno...