Growth factor-defined culture medium for human mesenchymal stem cells [0.03%]
人 mesenchymal 干细胞的生长因子定义培养基
Sumiyo Mimura,Naohiro Kimura,Mitsuhi Hirata et al.
Sumiyo Mimura et al.
Human bone marrow-derived mesenchymal stem cells (hMSCs) are potential cellular sources of therapeutic stem cells as they have the ability to proliferate and differentiate into a wide array of mesenchymal cell types such as osteoblasts, cho...
Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells [0.03%]
人类胚胎干细胞和诱导多能干细胞在体外和体内的分化过程中线粒体生物合成及生物能量代谢的调节机制研究
Alessandro Prigione,James Adjaye
Alessandro Prigione
Reprogramming somatic cells to induced pluripotent stem (iPS) cells transforms differentiated cells to an embryonic stem (ES) cell-like state characterized by the acquisition of pluripotency and self-renewal capabilities. We recently demons...
Regulation of programmed cell death during neural induction in the chick embryo [0.03%]
鸡胚神经诱导过程中程序性细胞死亡的调节
Anna Gibson,Neil Robinson,Andrea Streit et al.
Anna Gibson et al.
To study early responses to neural inducing signals from the organizer (Hensen's node), a differential screen was performed in primitive streak stage chick embryos, comparing cells that had or had not been exposed to a node graft for 5 hour...
Comprehensive analysis of fibroblast growth factor receptor expression patterns during chick forelimb development [0.03%]
鸡前肢发育过程中成纤维细胞生长因子受体表达模式的全面分析
Caroline J Sheeba,Raquel P Andrade,Delphine Duprez et al.
Caroline J Sheeba et al.
Specific interactions between fibroblast growth factors (Fgf1-22) and their tyrosine kinase receptors (FgfR1-4) activate different signalling pathways that are responsible for the biological processes in which Fgf signalling is implicated d...
Expression pattern of iodotyrosine dehalogenase 1 (DEHAL1) during chick ontogeny [0.03%]
碘酪氨酸脱卤酶1(DEHAL1)在鸡胚发育过程中的表达模式研究
Anupama A Mathi,Tekchand C Gaupale,Corinne Dupuy et al.
Anupama A Mathi et al.
The iodotyrosine dehalogenase1 (DEHAL1) enzyme is a transmembrane protein that belongs to the nitroreductase family and shows a highly conserved N-terminal domain. DEHAL1 is present in the liver, kidney and thyroid of mammals. DEHAL1 is kno...
Generation of germ-line chimera zebrafish using primordial germ cells isolated from cultured blastomeres and cryopreserved embryoids [0.03%]
利用体外培养卵裂球分离的原始生殖细胞和冷冻保存的胚胎样体制备嵌合体品系斑马鱼
Yutaka Kawakami,Rie Goto-Kazeto,Taiju Saito et al.
Yutaka Kawakami et al.
Primordial germ cells (PGCs) are the only cells in developing embryos with the potential to transmit genetic information to the next generation. In our previous study, a single PGC transplanted into a host differentiated into fertile gamete...
Rie Goto-Kazeto,Taiju Saito,Misae Takagi et al.
Rie Goto-Kazeto et al.
Primordial germ cells (PGCs) generate gametes, the only cells that can transmit genetic information to the next generation. A previous report demonstrated that a fusion construct of green fluorescent protein (gfp) and zebrafish nos 1 3UTR m...
A novel mutant allele of Ncx1: a single amino acid substitution leads to cardiac dysfunction [0.03%]
Ncx1的新突变等位基因：单一氨基酸替代引起心功能障碍
Carolien Wansleeben,Harma Feitsma,Leon Tertoolen et al.
Carolien Wansleeben et al.
The biological role and structure-function relationship of the Na(+)Ca(2+) exchanger NCX1 have been the subject of much investigation. Subtle mutagenesis to study the function of a protein seems only feasible in in vitro systems, but geneti...
Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development [0.03%]
Six1在嗅觉上皮发育过程中产生功能性前体细胞时不可或缺
Keiko Ikeda,Ryoichiro Kageyama,Yuko Suzuki et al.
Keiko Ikeda et al.
The rodent olfactory epithelium (OE) is a good model system for studying the principles of stem and progenitor cell biology, because of its capacity for continuous neurogenesis throughout life and relatively well-characterized neuronal line...
Transplantation of Xenopus laevis ears reveals the ability to form afferent and efferent connections with the spinal cord [0.03%]
非洲爪蟾耳朵的移植揭示了与脊髓形成传入和传出连接的能力
Karen L Elliott,Bernd Fritzsch
Karen L Elliott
Previous comparative and developmental studies have suggested that the cholinergic inner ear efferent system derives from developmentally redirected facial branchial motor neurons that innervate the vertebrate ear hair cells instead of stri...