DYRK2 drives renal fibrosis through CDK1-dependent G2/M phase dysregulation in tubular epithelial cells [0.03%]
DYRK2通过依赖CDK1的近曲肾小管上皮细胞G2/M期失调驱动肾纤维化
Fang Bai,Chunjie Wang,Sha Wang et al.
Fang Bai et al.
Ribbon constrains dendritic pruning via actin scaffolding and exocyst complex [0.03%]
丝带通过肌动蛋白支架和分泌衔接复合体限制树突修剪
Wanting Wang,Su Wang,Yuhao Yuan et al.
Wanting Wang et al.
Palmitoylation-dependent regulation of innate and adaptive immunity: molecular insights and translational opportunities [0.03%]
棕榈酰化调节固有免疫和适应性免疫：分子见解与转化机遇
Binhui Zhou,Bowen Zhang,Yingcheng Qi et al.
Binhui Zhou et al.
Targeting mutant p53 in cancer: from mechanistic insights to therapeutic strategies [0.03%]
靶向癌细胞突变型p53：从机制研究到治疗策略
H Helena Wu,Sarah Leng,David D Eisenstat et al.
H Helena Wu et al.
Li Gong,Xinyu Lu,Na Ma et al.
Li Gong et al.
CDH4/UBA1/RBMX axis promotes polycystic ovary syndrome progression through YAP1 activation [0.03%]
CDH4/UBA1/RBMX轴通过激活YAP1促进多囊卵巢综合征的发展
Ning Xu,Bo Yu,Yingying Li et al.
Ning Xu et al.
Therapeutic potential of 20-Hydroxyecdysone in pulmonary arterial hypertension: involvement of Mas receptor and PI3K-Akt pathway [0.03%]
20-羟基蜕皮酮治疗肺动脉高压的潜在作用及Mas受体和PI3K-Akt通路的介导作用研究
Tong Lu,Weiwei Jia,Yuefei Wang et al.
Tong Lu et al.
Background: 20-Hydroxyecdysone (20E), a natural polyhydroxylated steroid found in various edible plants, exhibits diverse pharmacological effects. Pulmonary arterial hypertension (PAH) remains challenging to treat owing t...
Macrophage-derived legumain ameliorates excessive mechanical stress-induced ferroptosis of nucleus pulposus cells and intervertebral disc degeneration via integrin αvβ3-Hippo signaling [0.03%]
巨噬细胞来源的半乳糖苷酶通过整合素αvβ3-Hippo信号通路改善椎间盘细胞铁死亡和椎间盘退变中的过度机械应力损伤
Peiyang Wang,Zhiyang Xie,Liting Deng et al.
Peiyang Wang et al.
Ash2l deficiency impairs adipose tissue thermogenesis and exacerbates obesity in mice [0.03%]
ASH2L缺陷通过损害脂肪组织产热促进肥胖发展
Yajie Hu,Jialin Zhao,Chenxi Xiao et al.
Yajie Hu et al.
Background: Epigenetic regulation plays a pivotal role in adipocyte development and thermogenesis. Ash2l, a key component of the COMPASS (Complex of Proteins Associated with Set1) histone methyltransferase, regulates gene...
Targeting dormant cancer cells: ferroptosis as a precision therapeutic strategy [0.03%]
针对休眠的癌细胞：铁死亡作为精准治疗策略
Sijia Hao,Yulu Guo,Qiaozhen Huang et al.
Sijia Hao et al.