Evaluation of neurogranin levels in a rat model of diffuse axonal injury [0.03%]
评价神经颗粒素在弥漫性轴索损伤大鼠模型中的水平变化
Ozan Baskurt,Seckin Aydin,Idris Avci et al.
Ozan Baskurt et al.
Diffuse axonal injury (DAI), one of the most common and devastating type of traumatic brain injury, is the result of the shear force on axons due to severe rotational acceleration and deceleration. Neurogranin (NRGN) is a postsynaptic prote...
The effect of morphine administration on GluN3B NMDA receptor subunit mRNA expression in rat brain [0.03%]
吗啡对大鼠脑GluN3B受体亚基mRNA表达的影响
Shahrzad Nazari,Mitra-Sadat Sadat-Shirazi,Ali Shahbazi et al.
Shahrzad Nazari et al.
Opioid addiction is critically dependent on the activation of N‑methyl‑D‑aspartate (NMDA) receptors, which are widely found in the mesocorticolimbic system. Meanwhile, opioid addiction may affect the expression level of NMDA receptor sub...
A novel insight into the neuroprotective effects of cannabidiol: maintained apelin/dopamine synthesis, NRF2 signaling, and AKT/CREB/BDNF gene expressions [0.03%]
大麻二酚神经保护作用的新见解：维持apeclin/多巴胺合成，NRF2信号传导和AKT / CREB / BDNF基因表达
Melike Doğan Ünlü,Sanem Aşçı,Orhan İmeci et al.
Melike Doğan Ünlü et al.
Neuroinflammation is a process associated with degeneration and loss of neurons in different parts of the brain. The most important damage mechanisms in its formation are oxidative stress and inflammation. This study aimed to investigate th...
Pylabianca: comprehensive and user‑friendly Python package for single‑neuron data analysis [0.03%]
Pylabianca：用于单神经元数据分析的综合易用Python包
Mikołaj Magnuski,Władysław Średniawa,Katarzyna Paluch et al.
Mikołaj Magnuski et al.
In the area of electrophysiology, the availability of comprehensive and user‑friendly tools for single-neuron data processing, statistical analysis, and fast, intuitive data visualization is limited. To address this gap, we introduce pylab...
Magdalena Mlostek,Juan Zeng,Malgorzata Urbanska et al.
Magdalena Mlostek et al.
Dendritogenesis, a process of dendritic arbor development, is essential for the formation of functional neuronal networks, and in mammals, it begins in early life and continues into adulthood. It is a highly dynamic process in which dendrit...
The less complex temporal patterns of resting‑state EEG activity, the lower the visual temporal order threshold [0.03%]
静息态EEG活动的时间模式越简单，则视觉时间顺序阈值越低
Monika Lewandowska,Krzysztof Tołpa,Marcin Hajnowski et al.
Monika Lewandowska et al.
Speech understanding, watching a movie, listening to music etc., requires perception of the temporal order of at least two incoming events. A history of performing these tasks may be reflected in spontaneous brain activity. Here, we examine...
The protective role of circ_0016760 downregulation against sevoflurane‑induced neurological impairment via modulating miR‑145 expression in aged rats [0.03%]
circ_0016760下调通过调节miR-145表达在老年大鼠七氟醚诱导的神经损伤中起到保护作用
Peiyu Shuai,Zhihong Hu,Wei Li et al.
Peiyu Shuai et al.
Sevoflurane can produce toxicity to the hippocampal tissues of brain, leading to nerve damage, causing learning and cognitive dysfunction. CircRNAs have been indicated to act as a key mediator in anesthetic neurotoxicity. This study focused...
Systematic review and meta‑analysis of observational studies to check the protective role of non‑steroidal anti‑inflammatory drugs in Alzheimer's disease [0.03%]
系统回顾和荟萃分析观察性研究以验证非甾体抗炎药对阿尔茨海默病的保护作用
Akash Asthana,Shashank Tripathi,Rachna Agarwal
Akash Asthana
Alzheimer's disease (AD) is a major neurodegenerative disease, affecting more than two third cases of dementia in the world. Non‑steroidal anti‑inflammatory drugs (NSAIDs) are widely used anti‑inflammatory analgesic agents representing 7...
Effect of low‑frequency repetitive transcranial magnetic stimulation on cognitive function in rats with medial temporal lobe epilepsy [0.03%]
低频重复经颅磁刺激对内侧颞叶癫痫大鼠认知功能的影响
Li-Qin Che,Zhen-Zhen Qu,Tao Xie et al.
Li-Qin Che et al.
Epilepsy, especially the medial temporal lobe epilepsy (TLE), can result in cognitive impairment. Low‑frequency repetitive magnetic stimulation (rTMS) has been verified to suppress neural excitability and reduce seizures. Given its potenti...
Anna Sługocka,Marta Anna Przybyła,Jarosław Jerzy Barski
Anna Sługocka
Tsc1 is a gene which expression results in hamartin, a protein involved in regulation of the mTOR1 pathway. Inactivation of Tsc1 gives rise to hyperactivation of the mTOR1 machinery, increased proliferation and growth of cells with subseque...