Pharmacological modulation of anxiety‑like and depression‑like behaviors in nerve‑ligated mice: regarding the effects of citicoline and bupropion [0.03%]
胞磷胆碱和安非他酮对坐骨神经结扎小鼠焦虑样和抑郁样行为的药理学调节作用研究
Bardia Hajikarimloo,Negar Raissi-Dehkordi,Nastaran Raissi-Dehkordi et al.
Bardia Hajikarimloo et al.
Neuropathic pain is a condition that results from nerve injury. There is a relationship between neuropathic pain and mood disorders. Citicoline, when used as a dietary supplement, exhibits neuroprotective, antidepressant, and anxiolytic pro...
Projections from thalamic nucleus reuniens to medial septum enable extinction of remote fear memory [0.03%]
背侧丘脑联合核到腹内侧海马区的投射促进远期恐惧记忆的消退
Kamil F Tomaszewski,Olga Gajewska-Woźniak,Magdalena Ziółkowska et al.
Kamil F Tomaszewski et al.
Aversive experiences lead to the formation of long‑lasting memories. Despite the need to better understand how enduring fear memories can be attenuated, the underlying brain circuits remain largely unknown. In this study, employing a combi...
Chronic pinacidil attenuates the pentylenetetrazole‑induced kindling in rats [0.03%]
慢性平阳霉素减轻戊四唑诱导的大鼠类痫发作
Artur Teixeira Pereira,Erica Aparecida Gelfuso,Luiz Luciano Falconi-Sobrinho et al.
Artur Teixeira Pereira et al.
Seizures in epilepsy result from excessive neuronal electrical discharges. Imbalances in potassium homeostasis can increase neuronal excitability and trigger epileptic seizures. Drugs that enhance potassium currents are expected to suppress...
Effects of adrenergic receptor modulators on nuclear LCC‑channels in Purkinje neurons [0.03%]
肾上腺素受体调节剂对浦肯野神经元核LCC通道的影响
Olena Kotyk,Serhii Nadtoka,Tetiana Vynohradova et al.
Olena Kotyk et al.
Large conductance cation channels (LCC‑channels), located in the nuclear membrane, are potential mediators of potassium (K+) countercurrent during calcium ion (Ca2+) release from intracellular stores. This study examined the effects of epi...
Slow‑releasing CO donor CORM‑A1 modulates depression‑like behavior in experimental model of chronic prostatitis/chronic pelvic pain syndrome [0.03%]
缓慢释放的供体CORM-A1调节慢性前列腺炎/慢性骨盆疼痛综合征实验模型中的类似抑郁行为
Nikola Šutulović,Neriman Ezgin,Emilija Đjurić et al.
Nikola Šutulović et al.
Chronic pain conditions are often linked with depression, a common chronic mental health disorder that severely impairs quality of life. This association is particularly present in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)....
Molecular and circuit mechanisms underlying interhemispheric communication in the mammalian brain [0.03%]
哺乳动物大脑半球间通信的分子和回路机制
Jan Jabłonka,Anna Sztencel,Magdalena Rucińska et al.
Jan Jabłonka et al.
Interhemispheric communication is a fundamental feature of the mammalian brain, supporting the bilateral integration of sensory, motor, cognitive, and emotional processes. While the corpus callosum has long been recognized as the principal ...
The role of prefrontal somatostatin interneurons in emotional contagion [0.03%]
前扣带皮层生长抑素阳性中间神经元在情绪传染中的作用研究
Tomasz Nikolaev,Emilia Goszczyńska,Natalia Roszkowska et al.
Tomasz Nikolaev et al.
The role of prefrontal somatostatin interneurons in emotion recognition is well characterized. Here, for the first time, we investigated the role of these neurons during remote transfer of emotional information in the safe environment of th...
Lack of unconventional myosin VI is associated with brain enlargement and gliosis progressing with age [0.03%]
缺少非常规肌球蛋白VI与进行性脑增大及随年龄增长的胶质细胞增生有关
Jolanta Nowak,Justyna Karolczak,Henryk Bilski et al.
Jolanta Nowak et al.
Myosin VI (MVI) is a unique unconventional myosin which, unlike other myosins, moves towards the minus end of actin filaments. It is involved in numerous cellular processes such as endocytosis and trafficking, cell migration and adhesion, a...
Astrocytic neurotransmitter receptors (astro‑glioreceptors) and their role in neuroplasticity [0.03%]
天冬氨酰胶质细胞受体及其在神经可塑性中的作用
Monika Liguz-Lęcznar,Malgorzata Kossut
Monika Liguz-Lęcznar
Astrocytes express a set of neurotransmitter receptors (glioreceptors) that enable them to regulate synaptic transmission and neuroplasticity, and to function as integral partners in synaptic signaling and the modification of neural circuit...
Analysis of gene expression and biological processes in the Wallerian degeneration segments of rat distal nerves [0.03%]
大鼠远端神经Waller变性节段基因表达及生物学过程分析
Zhengming Wang,Yichun He,Yushan Guo et al.
Zhengming Wang et al.
Peripheral nerve injuries occur due to accidents and in manufacturing every day. Unlike the central nervous system, injured peripheral nerves can self‑regenerate after injury. The study explored changes in gene expression and related biolo...