Mesenchymal stem cells for cardiac regeneration: translation to bedside reality [0.03%]
间充质干细胞心脏再生研究:从实验室到临床现实
Mohammad T Elnakish,Fatemat Hassan,Duaa Dakhlallah et al.
Mohammad T Elnakish et al.
Cardiovascular disease (CVD) is the leading cause of death worldwide. According to the World Health Organization (WHO), an estimate of 17.3 million people died from CVDs in 2008 and by 2030, the number of deaths is estimated to reach almost...
Large Pore Ion and Metabolite-Permeable Channel Regulation of Postnatal Ventricular Zone Neural Stem and Progenitor Cells: Interplay between Aquaporins, Connexins, and Pannexins? [0.03%]
大型离子和代谢物通透通道调节产后心室区神经干细胞和前体细胞:水孔蛋白、连接蛋白和泛素蛋白的相互作用?
Leigh E Wicki-Stordeur,Leigh Anne Swayne
Leigh E Wicki-Stordeur
The birth of new neurons from unspecialized neural stem and progenitor cells surrounding the lateral ventricles occurs throughout postnatal life. This process, termed neurogenesis, is complex and multistepped, encompassing several types of ...
Transplanted bone marrow mesenchymal stem cells improve memory in rat models of Alzheimer's disease [0.03%]
骨髓间充质干细胞移植改善阿尔茨海默病模型大鼠学习记忆障碍
Parvin Babaei,Bahram Soltani Tehrani,Arsalan Alizadeh
Parvin Babaei
The present study aims to evaluate the effect of bone marrow mesenchymal stem cells (MSCs) grafts on cognition deficit in chemically and age-induced Alzheimer's models of rats. In the first experiments aged animals (30 months) were tested i...
Journey of mesenchymal stem cells for homing: strategies to enhance efficacy and safety of stem cell therapy [0.03%]
间充质干细胞归巢的旅程:提高干细胞治疗有效性和安全性的策略
Sung Keun Kang,Il Seob Shin,Myung Soon Ko et al.
Sung Keun Kang et al.
Human mesenchymal stem cells (MSCs) communicate with other cells in the human body and appear to "home" to areas of injury in response to signals of cellular damage, known as homing signals. This review of the state of current research on h...
Neural stem cells in Drosophila: molecular genetic mechanisms underlying normal neural proliferation and abnormal brain tumor formation [0.03%]
果蝇中的神经干细胞:调控正常神经细胞增殖和异常脑肿瘤形成的分子遗传机制
Nidhi Saini,Heinrich Reichert
Nidhi Saini
Neural stem cells in Drosophila are currently one of the best model systems for understanding stem cell biology during normal development and during abnormal development of stem cell-derived brain tumors. In Drosophila brain development, th...
Margit Rosner,Katharina Schipany,Bharanidharan Shanmugasundaram et al.
Margit Rosner et al.
The existence of stem cells in human amniotic fluid was reported for the first time almost ten years ago. Since this discovery, the knowledge about these cells has increased dramatically. Today, amniotic fluid stem (AFS) cells are widely ac...
Hematological- and Neurological-Expressed Sequence 1 Gene Products in Progenitor Cells during Newt Retinal Development [0.03%]
发育过程中新眼杯祖细胞中血液和神经表达序列1基因产物
Tatsushi Goto,Fumio Tokunaga,Osamu Hisatomi
Tatsushi Goto
Urodele amphibians such as Japanese common newts have a remarkable ability to regenerate their injured neural retina, even as adults. We found that hematological- and neurological-expressed sequence 1 (Hn1) gene was induced in depigmented r...
Comprehensive characterization of mesenchymal stem cells from human placenta and fetal membrane and their response to osteoactivin stimulation [0.03%]
人胎盘和胎儿膜间充质干细胞的全面表征及其对成骨活化素刺激的反应
C M Raynaud,M Maleki,R Lis et al.
C M Raynaud et al.
Mesenchymal stem cells (MSCs) are the most promising seed cells for cell therapy and can be isolated from various sources of human adult tissues such as bone marrow (BM-MSC) and adipose tissue. However, cells from these tissues must be obta...
Induction therapy and stem cell mobilization in patients with newly diagnosed multiple myeloma [0.03%]
新诊断的多发性骨髓瘤患者的诱导治疗和干细胞动员
Roberto Ria,Antonia Reale,Antonio Giovanni Solimando et al.
Roberto Ria et al.
Autologous stem cell transplantation (ASCT) is considered the standard therapy for younger patients with newly diagnosed symptomatic multiple myeloma (MM). The introduction into clinical practice of novel agents, such as the proteasome inhi...
Maria G Roubelakis,Ourania Trohatou,Nicholas P Anagnou
Maria G Roubelakis
Amniotic fluid (AF) and amniotic membrane (AM) have been recently characterized as promising sources of stem or progenitor cells. Both not only contain subpopulations with stem cell characteristics resembling to adult stem cells, such as me...