Human embryonic stem cell responses to ionizing radiation exposures: current state of knowledge and future challenges [0.03%]
人胚胎干细胞对电离辐射的反应：现状与未来挑战
Mykyta V Sokolov,Ronald D Neumann
Mykyta V Sokolov
Human embryonic stem cells, which are derived from the inner cell mass of the blastocyst, have become an object of intense study over the last decade. They possess two unique properties that distinguish them from many other cell types: (i) ...
Retinal Pigment Epithelium and Müller Progenitor Cell Interaction Increase Müller Progenitor Cell Expression of PDGFRα and Ability to Induce Proliferative Vitreoretinopathy in a Rabbit Model [0.03%]
视网膜色素上皮与Müller源性前体细胞的相互作用可增强PDGFRA表达及兔模型下促进增生性玻璃体视网膜病变的能力
Gisela Velez,Alexa R Weingarden,Budd A Tucker et al.
Gisela Velez et al.
Purpose. Proliferative vitreoretinopathy (PVR) is a complication of retinal detachment characterized by redetachment of the retina as a result of membrane formation and contraction. A variety of retinal cells, including retinal pigment epit...
Heart cells with regenerative potential from pediatric patients with end stage heart failure: a translatable method to enrich and propagate [0.03%]
来自终末期心脏病的小患者具有再生能力的心脏细胞：一种富集和扩增的可转化的方法
Ann Steele,Robert J Boucek Jr,Jeffrey Phillip Jacobs et al.
Ann Steele et al.
Background. Human cardiac-derived progenitor cells (hCPCs) have shown promise in treating heart failure (HF) in adults. The purpose of this study was to describe derivation of hCPCs from pediatric patients with end-stage HF. Methods. At sur...
Joel Sng,Thomas Lufkin
Joel Sng
Stem cells are the fundamental building blocks of life and contribute to the genesis and development of all higher organisms. The discovery of adult stem cells has led to an ongoing revolution of therapeutic and regenerative medicine and th...
Serena Pillozzi,Andrea Becchetti
Serena Pillozzi
Hematopoietic stem cells (HSCs) reside in bone marrow niches and give rise to hematopoietic precursor cells (HPCs). These have more restricted lineage potential and eventually differentiate into specific blood cell types. Bone marrow also c...
Development of a vascularized skin construct using adipose-derived stem cells from debrided burned skin [0.03%]
利用烧伤脱痂皮肤来源的脂肪干细胞构建血管化皮肤组织工程种子细胞杂交床模型研究
Rodney K Chan,David O Zamora,Nicole L Wrice et al.
Rodney K Chan et al.
Large body surface area burns pose significant therapeutic challenges. Clinically, the extent and depth of burn injury may mandate the use of allograft for temporary wound coverage while autografts are serially harvested from the same donor...
Masayuki Yamashita
Masayuki Yamashita
During the embryonic development of the central nervous system, neuroepithelial cells act as neural stem cells. They undergo interkinetic nuclear movements along their apico-basal axis during the cell cycle. The neuroepithelial cell shows r...
Rajarshi Pal,Mahendra Rao,Mohan C Vemuri et al.
Rajarshi Pal et al.
Development of a functional schwann cell phenotype from autologous porcine bone marrow mononuclear cells for nerve repair [0.03%]
自体猪骨髓单个核细胞向施万细胞功能表型分化用于神经修复
Michael J Rutten,Michael Ann Janes,Ivy R Chang et al.
Michael J Rutten et al.
Adult bone marrow mononuclear cells (BM-MNCs) are a potential resource for making Schwann cells to repair damaged peripheral nerves. However, many methods of producing Schwann-like cells can be laborious with the cells lacking a functional ...
Human amniotic fluid cells form functional gap junctions with cortical cells [0.03%]
人羊水细胞与皮层细胞形成功能性缝隙连接
Anna Jezierski,Kerry Rennie,Roger Tremblay et al.
Anna Jezierski et al.
The usage of stem cells is a promising strategy for the repair of damaged tissue in the injured brain. Recently, amniotic fluid (AF) cells have received a lot of attention as an alternative source of stem cells for cell-based therapies. How...