Enhanced healing of diabetic wounds by topical administration of adipose tissue-derived stromal cells overexpressing stromal-derived factor-1: biodistribution and engraftment analysis by bioluminescent imaging [0.03%]
糖尿病伤口局部应用过表达基质细胞衍生因子的脂肪组织基质细胞可加速创面愈合：生物发光成像引导下的分布定植分析
Giuliana Di Rocco,Antonietta Gentile,Annalisa Antonini et al.
Giuliana Di Rocco et al.
Chronic ulcers represent a major health problem in diabetic patients resulting in pain and discomfort. Conventional therapy does not guarantee adequate wound repair. In diabetes, impaired healing is partly due to poor endothelial progenitor...
Cotransplantation of adipose tissue-derived insulin-secreting mesenchymal stem cells and hematopoietic stem cells: a novel therapy for insulin-dependent diabetes mellitus [0.03%]
脂肪组织来源的胰岛素分泌间充质干细胞和造血干细胞共移植治疗胰岛素依赖型糖尿病的新疗法
A V Vanikar,S D Dave,U G Thakkar et al.
A V Vanikar et al.
Aims. Insulin dependent diabetes mellitus (IDDM) is believed to be an autoimmune disorder with disturbed glucose/insulin metabolism, requiring life-long insulin replacement therapy (IRT), 30% of patients develop end-organ failure. We presen...
Vascular guidance: microstructural scaffold patterning for inductive neovascularization [0.03%]
血管导向：诱导新生血管形成的微结构支架图案设计
Daniel Muller,Harvey Chim,Augustinus Bader et al.
Daniel Muller et al.
Current tissue engineering techniques are limited by inadequate vascularisation and perfusion of cell-scaffold constructs. Microstructural patterning through biomimetic vascular channels within a polymer scaffold might induce neovasculariza...
Noncultured autologous adipose-derived stem cells therapy for chronic radiation injury [0.03%]
自体脂肪来源干细胞治疗慢性放射损伤
Sadanori Akita,Kozo Akino,Akiyoshi Hirano et al.
Sadanori Akita et al.
Increasing concern on chronic radiation injuries should be treated properly for life-saving improvement of wound management and quality of life. Recently, regenerative surgical modalities should be attempted with the use of noncultured auto...
Clinical application of human mesenchymal stromal cells for bone tissue engineering [0.03%]
人源间充质基质细胞在骨组织工程中的临床应用
Anindita Chatterjea,Gert Meijer,Clemens van Blitterswijk et al.
Anindita Chatterjea et al.
The gold standard in the repair of bony defects is autologous bone grafting, even though it has drawbacks in terms of availability and morbidity at the harvesting site. Bone-tissue engineering, in which osteogenic cells and scaffolds are co...
Ricardo Sanz-Ruiz,Enrique Gutiérrez Ibañes,Adolfo Villa Arranz et al.
Ricardo Sanz-Ruiz et al.
First randomized clinical trials have demonstrated that stem cell therapy can improve cardiac recovery after the acute phase of myocardial ischemia and in patients with chronic ischemic heart disease. Nevertheless, some trials have shown th...
Culture and Use of Mesenchymal Stromal Cells in Phase I and II Clinical Trials [0.03%]
间充质基质细胞的临床I期和II期试验中的文化和使用
Bourin Philippe,Sensebé Luc,Planat-Bénard Valérie et al.
Bourin Philippe et al.
Present in numerous tissues, mesenchymal stem cells/multipotent stromal cells (MSCs) can differentiate into different cell types from a mesoderm origin. Their potential has been extended to pluripotency, by their possibility of differentiat...
Alteration in marrow stromal microenvironment and apoptosis mechanisms involved in aplastic anemia: an animal model to study the possible disease pathology [0.03%]
骨髓基质微环境和凋亡机制在再生障碍性贫血发病中的作用：一个动物模型显示的可能病理变化
Sumanta Chatterjee,Ranjan Kumar Dutta,Pratima Basak et al.
Sumanta Chatterjee et al.
Aplastic anemia (AA) is a heterogeneous disorder of bone marrow failure syndrome. Suggested mechanisms include a primary stem cell deficiency or defect, a secondary stem cell defect due to abnormal regulation between cell death and differen...
Effect of bone marrow-derived mesenchymal stem cells on endotoxin-induced oxidation of plasma cysteine and glutathione in mice [0.03%]
骨髓间充质干细胞对内毒素诱导的小鼠血浆半胱氨酸和谷胱甘肽氧化的影响
Smita S Iyer,Edilson Torres-Gonzalez,David C Neujahr et al.
Smita S Iyer et al.
Bone marrow-derived mesenchymal stem cells (BMDMSC) are emerging as a therapeutic modality in various inflammatory disease states, including acute lung injury (ALI). A hallmark of inflammation, and a consistent observation in patients with ...
Leora J Tesche,David A Gerber
Leora J Tesche
The characterization and isolation of various stem cell populations, from embryonic through tissue-derived stem cells, have led a rapid growth in the field of stem cell research. These research efforts have often been interrelated as to the...