Secreted factors from bone marrow stromal cells upregulate IL-10 and reverse acute kidney injury [0.03%]
骨髓基质细胞分泌因子上调IL-10并逆转急性肾损伤
Jack M Milwid,Takaharu Ichimura,Matthew Li et al.
Jack M Milwid et al.
Acute kidney injury is a devastating syndrome that afflicts over 2,000,000 people in the US per year, with an associated mortality of greater than 70% in severe cases. Unfortunately, standard-of-care treatments are not sufficient for modify...
Parkinson's Disease in a Dish: What Patient Specific-Reprogrammed Somatic Cells Can Tell Us about Parkinson's Disease, If Anything? [0.03%]
Parkinson病的培养皿模型：患者特异性的重编体细胞对帕金森研究的意义何在？
J Drouin-Ouellet,R A Barker
J Drouin-Ouellet
Technologies allowing for the derivation of patient-specific neurons from somatic cells are emerging as powerful in vitro tools to investigate the intrinsic cellular pathological behaviours of the diseases that affect these patients. While ...
Ashley McDonough,Verónica Martínez-Cerdeño
Ashley McDonough
Spinal cord injury (SCI) results in motor and sensory deficits, the severity of which depends on the level and extent of the injury. Animal models for SCI research include transection, contusion, and compression mouse models. In this paper ...
Early growth response genes signaling supports strong paracrine capability of mesenchymal stem cells [0.03%]
早期生长反应基因信号传导支持间充质干细胞的强大旁分泌功能
Kenichi Tamama,Dominique J Barbeau
Kenichi Tamama
MSCs provide a promising method for cell therapy through their wound healing and tissue regenerative properties. Originally, MSCs' role in wound healing was thought to be tied to their multipotency, but it is now accepted that MSCs mediate ...
Characterization of Porcine Ventral Mesencephalic Precursor Cells following Long-Term Propagation in 3D Culture [0.03%]
三维培养长期扩增后原代猪中脑腹侧神经前体细胞的鉴定
Pia S Jensen,Lise Lyck,Pia Jensen et al.
Pia S Jensen et al.
The potential use of predifferentiated neural precursor cells for treatment of a neurological disorder like Parkinson's disease combines stem cell research with previous experimental and clinical transplantation of developing dopaminergic n...
Intrasplenic transplantation of bioencapsulated mesenchymal stem cells improves the recovery rates of 90% partial hepatectomized rats [0.03%]
生物封装间充质干细胞的肝内移植可改善大鼠90%部分肝切除术后恢复率
Zun Chang Liu,Thomas Ming Swi Chang
Zun Chang Liu
Mesenchymal stem cells (MSCs) derived from bone marrow can secrete cytokines and growth factors and can transdifferentiate into liver cells. We transplanted polymeric membrane bioencapsulated MSCs into the spleens of 90% partial hepatectomi...
Mahmud Bani-Yaghoub,Patricia Wilson,Markus Hengstschläger et al.
Mahmud Bani-Yaghoub et al.
Tomás P Bachor,Angela M Suburo
Tomás P Bachor
Experimental diabetes in rodents rapidly affects the neurogenic niches of the adult brain. Moreover, behavioral disorders suggest that a similar dysfunction of the neurogenic niches most likely affects diabetic and prediabetic patients. Her...
Ion flux dependent and independent functions of ion channels in the vertebrate heart: lessons learned from zebrafish [0.03%]
脊椎动物心脏中离子通道的离子流依赖和非依赖功能——从斑马鱼研究中得到的经验教训
Mirjam Keßler,Steffen Just,Wolfgang Rottbauer
Mirjam Keßler
Ion channels orchestrate directed flux of ions through membranes and are essential for a wide range of physiological processes including depolarization and repolarization of biomechanical activity of cells. Besides their electrophysiologica...
Oscar Gonzalez-Perez,Jose M Garcia-Verdugo,Alfredo Quinones-Hinojosa et al.
Oscar Gonzalez-Perez et al.