Kristiina Rajala,Mari Pekkanen-Mattila,Katriina Aalto-Setälä
Kristiina Rajala
The ability of human pluripotent stem cells to differentiate towards the cardiac lineage has attracted significant interest, initially with a strong focus on regenerative medicine. The ultimate goal to repair the heart by cardiomyocyte repl...
Cord blood-derived hematopoietic stem/progenitor cells: current challenges in engraftment, infection, and ex vivo expansion [0.03%]
脐带血造血干细胞/祖细胞：植入、感染及体外扩增的当前挑战
Katsuhiro Kita,Jong O Lee,Celeste C Finnerty et al.
Katsuhiro Kita et al.
Umbilical cord blood has served as an alternative to bone marrow for hematopoietic transplantation since the late 1980s. Numerous clinical studies have proven the efficacy of umbilical cord blood. Moreover, the possible immaturity of cells ...
Jeffrey M Gimble,Bruce A Bunnell,Louis Casteilla et al.
Jeffrey M Gimble et al.
Amniotic-Fluid Stem Cells: Growth Dynamics and Differentiation Potential after a CD-117-Based Selection Procedure [0.03%]
人羊水干细胞的生长特性和CD-117选择后分化潜能
S Arnhold,S Glüer,K Hartmann et al.
S Arnhold et al.
Amniotic fluid (AF) has become an interesting source of fetal stem cells. However, AF contains heterogeneous and multiple, partially differentiated cell types. After isolation from the amniotic fluid, cells were characterized regarding thei...
Martin H Maurer
Martin H Maurer
Mesenchymal stem cells (MSCs) are pluripotent cells isolated from the bone marrow and various other organs. They are able to proliferate and self-renew, as well as to give rise to progeny of at least the osteogenic, chondrogenic, and adipog...
Potential clinical applications for human pluripotent stem cell-derived blood components [0.03%]
人多能干细胞来源的血液成分的潜在临床应用
Erin A Kimbrel,Shi-Jiang Lu
Erin A Kimbrel
The ability of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) to divide indefinitely without losing pluripotency and to theoretically differentiate into any cell type in the body makes them highly attractive c...
Fibroblast Growth Factor-2 Enhances Expansion of Human Bone Marrow-Derived Mesenchymal Stromal Cells without Diminishing Their Immunosuppressive Potential [0.03%]
成纤维细胞生长因子-2可促进人骨髓间充质干细胞的扩增而不减弱其免疫抑制潜能
Jeffery J Auletta,Elizabeth A Zale,Jean F Welter et al.
Jeffery J Auletta et al.
Allogeneic hematopoietic stem cell transplantation is the main curative therapy for many hematologic malignancies. Its potential relies on graft-versus-tumor effects which associate with graft-versus-host disease. Mesenchymal stromal cells ...
Translating research into clinical scale manufacturing of mesenchymal stromal cells [0.03%]
关于间充质基质细胞临床规模生产的研究进展
Karen Bieback,Sven Kinzebach,Marianna Karagianni
Karen Bieback
It sounds simple to obtain sufficient numbers of cells derived from fetal or adult human tissues, isolate and/or expand the stem cells, and then transplant an appropriate number of these cells into the patient at the correct location. Howev...
Bone marrow-derived mesenchymal stem cells: current and future applications in the urinary bladder [0.03%]
骨髓源间充质干细胞在膀胱中的应用进展与展望
Beth A Drzewiecki,John C Thomas,Stacy T Tanaka
Beth A Drzewiecki
Mesenchymal stem cells can be isolated from almost any adult tissue. In this paper we focus on bone marrow-derived mesenchymal stem cells which have captured the interest of researchers since their introduction because of the promising pote...
Mesenchymal Progenitor Cells and Their Orthopedic Applications: Forging a Path towards Clinical Trials [0.03%]
间充质基质细胞及其在骨科的临床应用研究
Deana S Shenaq,Farbod Rastegar,Djuro Petkovic et al.
Deana S Shenaq et al.
Mesenchymal progenitor cells (MPCs) are nonhematopoietic multipotent cells capable of differentiating into mesenchymal and nonmesenchymal lineages. While they can be isolated from various tissues, MPCs isolated from the bone marrow are best...