Comparison of Gene Expression in Human Embryonic Stem Cells, hESC-Derived Mesenchymal Stem Cells and Human Mesenchymal Stem Cells [0.03%]
人胚胎干细胞与诱导的间充质干细胞及人间充质干细胞基因表达比较研究
Romain Barbet,Isabelle Peiffer,Antoinette Hatzfeld et al.
Romain Barbet et al.
We present a strategy to identify developmental/differentiation and plasma membrane marker genes of the most primitive human Mesenchymal Stem Cells (hMSCs). Using sensitive and quantitative TaqMan Low Density Arrays (TLDA) methodology, we c...
Transcription factor lbx1 expression in mouse embryonic stem cell-derived phenotypes [0.03%]
小鼠胚胎干细胞来源表型中转录因子Lbx1的表达
Stefanie Schmitteckert,Cornelia Ziegler,Liane Kartes et al.
Stefanie Schmitteckert et al.
Transcription factor Lbx1 is known to play a role in the migration of muscle progenitor cells in limb buds and also in neuronal determination processes. In addition, involvement of Lbx1 in cardiac neural crest-related cardiogenesis was post...
Natalia Lapteva,Juan F Vera
Natalia Lapteva
Although ex vivo expanded T cells are currently widely used in pre-clinical and clinical trials, the complexity of manufacture remains a major impediment for broader application. In this review we discuss current protocols for the ex vivo e...
Recovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγ mice [0.03%]
体外扩增的人红细胞注入NOD/SCID/IL2Rγ小鼠后的恢复和生物分布
Barbara Ghinassi,Leda Ferro,Francesca Masiello et al.
Barbara Ghinassi et al.
Ex vivo expanded erythroblasts (EBs) may serve as advanced transfusion products provided that lodgment occurs in the macrophage-niche of the marrow permitting maturation. EBs expanded from adult and cord blood expressed the receptors (CXCR4...
Embryonic stem cell-derived cardiomyocyte heterogeneity and the isolation of immature and committed cells for cardiac remodeling and regeneration [0.03%]
胚胎干细胞源性心肌细胞的异质性和未成熟及分化程度不同的心肌细胞在心脏重塑和再生中的分离研究
Kenneth R Boheler,Robert N Joodi,Hui Qiao et al.
Kenneth R Boheler et al.
Pluripotent stem cells represent one promising source for cell replacement therapy in heart, but differentiating embryonic stem cell-derived cardiomyocytes (ESC-CMs) are highly heterogeneous and show a variety of maturation states. In this ...
From banking to international governance: fostering innovation in stem cell research [0.03%]
从银行到国际治理：促进干细胞研究的创新
Rosario Isasi,Bartha M Knoppers
Rosario Isasi
Stem cell banks are increasingly recognized as an essential resource of biological materials for both basic and translational stem cell research. By providing transnational access to quality controlled and ethically sourced stem cell lines,...
Alexander Kleger,Stefan Liebau,Qiong Lin et al.
Alexander Kleger et al.
Lysophospholipids comprise a group of bioactive molecules with multiple biological functions. The cardinal members of this signalling molecule group are sphingosylphosphorylcholine (SPC), lysophosphatidic acid (LPA), and sphingosine 1-phosp...
In vitro differentiation and maturation of human embryonic stem cell into multipotent cells [0.03%]
人胚胎干细胞体外向多能细胞的分化和成熟研究
Amer Mahmood,Claudio Napoli,Abdullah Aldahmash
Amer Mahmood
Human embryonic stem cells (hESCs), which have the potential to generate virtually any differentiated progeny, are an attractive cell source for transplantation therapy, regenerative medicine, and tissue engineering. To realize this potenti...
Khushnuma Cooper,Chandra Viswanathan
Khushnuma Cooper
Adult stem cells have generated great amount of interest amongst the scientific community for their potential therapeutic applications for unmet medical needs. We have demonstrated the plasticity of mesenchymal stem cells isolated from the ...
Preclinical studies on mesenchymal stem cell-based therapy for growth plate cartilage injury repair [0.03%]
基于间充质干细胞的生长板软骨损伤修复治疗的临床前研究
Rosa Chung,Bruce K Foster,Cory J Xian
Rosa Chung
In the last two decades, there has been a strong interest in searching for biological treatments for regeneration of injured growth plate cartilage and prevention of its bony repair. Various means have been tried, including implantation of ...