Adult-brain-derived neural stem cells grafting into a vein bridge increases postlesional recovery and regeneration in a peripheral nerve of adult pig [0.03%]
成人脑源性神经干细胞嫁接到静脉桥提高成年猪外周神经损伤后的修复和再生能力
Olivier Liard,Stéphanie Segura,Emmanuel Sagui et al.
Olivier Liard et al.
We attempted transplantation of adult neural stem cells (ANSCs) inside an autologous venous graft following surgical transsection of nervis cruralis with 30 mm long gap in adult pig. The transplanted cell suspension was a primary culture of...
In vivo healing of meniscal lacerations using bone marrow-derived mesenchymal stem cells and fibrin glue [0.03%]
骨髓间充质干细胞与纤维蛋白胶修复半月板裂伤的实验研究
Dora Ferris,David Frisbie,John Kisiday et al.
Dora Ferris et al.
Fibrin glue created from a patient's own blood can be used as a carrier to deliver cells to the specific site of an injury. An experimental model for optimizing various permutations of this delivery system in vivo was tested in this study. ...
The effect of human and mouse fibroblast feeder cells on cardiac differentiation of human pluripotent stem cells [0.03%]
人胚系干细胞分化为人心脏细胞的三维培养体系及其机制研究
Mari Pekkanen-Mattila,Marisa Ojala,Erja Kerkelä et al.
Mari Pekkanen-Mattila et al.
Mouse embryonic fibroblasts (MEFs) and human foreskin fibroblasts (hFFs) are commonly used as feeder cells to maintain the pluripotent state of stem cells. The aim of the present study was to evaluate the effect of MEF and hFF feeders on th...
Mesenchymal stem cells and cardiovascular disease: a bench to bedside roadmap [0.03%]
间充质干细胞与心血管疾病：从实验台到病人的路线图
Manuel Mazo,Miriam Araña,Beatriz Pelacho et al.
Manuel Mazo et al.
In recent years, the incredible boost in stem cell research has kindled the expectations of both patients and physicians. Mesenchymal progenitors, owing to their availability, ease of manipulation, and therapeutic potential, have become one...
Ligament tissue engineering and its potential role in anterior cruciate ligament reconstruction [0.03%]
韧带组织工程及其在前交叉韧带重建中的潜在作用
E W Yates,A Rupani,G T Foley et al.
E W Yates et al.
Tissue engineering is an emerging discipline that combines the principle of science and engineering. It offers an unlimited source of natural tissue substitutes and by using appropriate cells, biomimetic scaffolds, and advanced bioreactors,...
Multipotent Mesenchymal Stromal Cells for the Prophylaxis of Acute Graft-versus-Host Disease-A Phase II Study [0.03%]
间充质基质细胞预防急性移植物抗宿主病-II期临床研究
Larisa A Kuzmina,Natalia A Petinati,Elena N Parovichnikova et al.
Larisa A Kuzmina et al.
The efficacy and the safety of the administration of multipotent mesenchymal stromal cells (MMSCs) for acute graft-versus-host disease (aGVHD) prophylaxis following allogeneic hematopoietic cell transplantation (HSCT) were studied. This pro...
Caglar Yilgor,Pinar Yilgor Huri,Gazi Huri
Caglar Yilgor
Ligaments are dense fibrous connective tissues that connect bones to other bones and their injuries are frequently encountered in the clinic. The current clinical approaches in ligament repair and regeneration are limited to autografts, as ...
Treatment of chronic patellar tendinopathy with autologous bone marrow stem cells: a 5-year-followup [0.03%]
自体骨髓干细胞治疗慢性髌腱病的五年随访研究
Cecilia Pascual-Garrido,A Rolón,A Makino
Cecilia Pascual-Garrido
The purpose of this study is to determine if patients with chronic patellar tendinopathy will improve clinically after the inoculation of bone marrow mononuclear cells (BM-MNCs). Eight patients with chronic patellar tendinopathy were includ...
Biological strategies to enhance healing of the avascular area of the meniscus [0.03%]
改善半月板血管少区域愈合的生物策略
Umile Giuseppe Longo,Stefano Campi,Giovanni Romeo et al.
Umile Giuseppe Longo et al.
Meniscal injuries in the vascularized peripheral part of the meniscus have a better healing potential than tears in the central avascular zone because meniscal healing principally depends on its vascular supply. Several biological strategie...
The potential of stem cells in the treatment of skeletal muscle injury and disease [0.03%]
干细胞在骨骼肌损伤和疾病治疗中的潜力
S Maclean,W S Khan,A A Malik et al.
S Maclean et al.
Tissue engineering is a pioneering field with huge advances in recent times. These advances are not only in the understanding of how cells can be manipulated but also in potential clinical applications. Thus, tissue engineering, when applie...