Optimization of parameters for a more efficient use of adipose-derived stem cells in regenerative medicine therapies [0.03%]
用于再生医学疗法的脂肪来源干细胞更有效利用的参数优化
Meire Aguena,Roberto Dalto Fanganiello,Luiz Alexandre Lorico Tissiani et al.
Meire Aguena et al.
Adipose tissue-derived stem cells (ASCs) association to fat in autologous lipotransfer is promising for a more effective soft tissue reconstruction, and optimization of protocols to isolate ASCs from lipoaspirate fat is much needed. We demo...
The influence of brightness on functional assessment by mferg: a study on scaffolds used in retinal cell transplantation in pigs [0.03%]
亮度对mFERG功能评估影响的研究-用于猪视网膜细胞移植的支架研究
A T Christiansen,J F Kiilgaard,M Smith et al.
A T Christiansen et al.
To determine the effect of membrane brightness on multifocal electroretinograms (mfERGs), we implanted poly lactic-co-glycolic acid (PLGA) membranes in the subretinal space of 11 porcine eyes. We compared membranes with their native shiny w...
Histone deacetylase inhibitors in cell pluripotency, differentiation, and reprogramming [0.03%]
组蛋白脱乙酰基酶抑制剂与细胞多能性、分化和重编程
Androniki Kretsovali,Christiana Hadjimichael,Nikolaos Charmpilas
Androniki Kretsovali
Histone deacetylase inhibitors (HDACi) are small molecules that have important and pleiotropic effects on cell homeostasis. Under distinct developmental conditions, they can promote either self-renewal or differentiation of embryonic stem c...
Long-term cultured human term placenta-derived mesenchymal stem cells of maternal origin displays plasticity [0.03%]
长期培养的人体足月胎盘源性母体间充质干细胞的可塑性
Vikram Sabapathy,Saranya Ravi,Vivi Srivastava et al.
Vikram Sabapathy et al.
Mesenchymal stem cells (MSCs) are an alluring therapeutic resource because of their plasticity, immunoregulatory capacity and ease of availability. Human BM-derived MSCs have limited proliferative capability, consequently, it is challenging...
Umile Giuseppe Longo,Stefano Petrillo,Edoardo Franceschetti et al.
Umile Giuseppe Longo et al.
Cartilage defects represent a common problem in orthopaedic practice. Predisposing factors include traumas, inflammatory conditions, and biomechanics alterations. Conservative management of cartilage defects often fails, and patients with t...
Elham Zomorodian,Mohamadreza Baghaban Eslaminejad
Elham Zomorodian
While small bone defects heal spontaneously, large bone defects need surgical intervention for bone transplantation. Autologous bone grafts are the best and safest strategy for bone repair. An alternative method is to use allogenic bone gra...
Mark Young
Mark Young
Tendon injuries are a common cause of morbidity and a significant health burden on society. Tendons are structural tissues connecting muscle to bone and are prone to tearing and tendinopathy, an overuse or degenerative condition that is cha...
Prospect of induced pluripotent stem cell genetic repair to cure genetic diseases [0.03%]
诱导多能干细胞基因修正治疗遗传病的前景
Jeanne Adiwinata Pawitan
Jeanne Adiwinata Pawitan
In genetic diseases, where the cells are already damaged, the damaged cells can be replaced by new normal cells, which can be differentiated from iPSC. To avoid immune rejection, iPSC from the patient's own cell can be developed. However, i...
Optimising human mesenchymal stem cell numbers for clinical application: a literature review [0.03%]
优化人骨髓间充质干细胞临床应用数量的文献回顾研究论文
E Fossett,W S Khan
E Fossett
Adult mesenchymal stem cells (MSCs) are being investigated further for their use in stem cell therapies. However, as they are found in very low numbers in adult tissue, expansion in vitro is required to produce desired MSC numbers for clini...
Kevin S Tieu,Ryan S Tieu,Julian A Martinez-Agosto et al.
Kevin S Tieu et al.
The stem cell microenvironment is involved in regulating the fate of the stem cell with respect to self-renewal, quiescence, and differentiation. Mathematical models are helpful in understanding how key pathways regulate the dynamics of ste...