Feline neural progenitor cells II: use of novel plasmid vector and hybrid promoter to drive expression of glial cell line-derived neurotrophic factor transgene [0.03%]
猫神经干细胞II：使用新型质粒载体和杂合启动子驱动胶质细胞系源性神经营养因子转基因表达
X Joann You,Jing Yang,Ping Gu et al.
X Joann You et al.
Sustained transgene expression is required for the success of cell transplant-based gene therapy. Most widely used are lentiviral-based vectors which integrate into the host genome and thereby maintain sustained transgene expression. This r...
Generation of human-induced pluripotent stem cells by a nonintegrating RNA Sendai virus vector in feeder-free or xeno-free conditions [0.03%]
在无饲养层或无异种条件下利用非整合型RNA沙甸病毒载体生成人诱导多能干细胞
Chad C Macarthur,Andrew Fontes,Namritha Ravinder et al.
Chad C Macarthur et al.
The generation of induced pluripotent stem cells (iPSCs) from somatic cells has enabled the possibility of providing unprecedented access to patient-specific iPSC cells for drug screening, disease modeling, and cell therapy applications. Ho...
Kenji Okumura,Masanori Shinohara,Fumio Endo
Kenji Okumura
Branching morphogenesis (BrM), an essential step for salivary gland development, requires epithelial-mesenchymal interactions. BrM is impaired when the surrounding mesenchyme is detached from the salivary epithelium during the pseudoglandul...
Subretinal implantation of electrospun, short nanowire, and smooth poly(ε-caprolactone) scaffolds to the subretinal space of porcine eyes [0.03%]
短纳米线和光滑聚-ε-己内酯支架的静电纺丝子视网膜下植入物放入猪眼睛的子视网膜空间中
A T Christiansen,S L Tao,M Smith et al.
A T Christiansen et al.
Biodegradable scaffolds play an important adjunct role in transplantation of retinal progenitor cells (RPCs) to the subretinal space. Poly(ε-Caprolactone) (PCL) scaffolds with different modifications were subretinally implanted in 28 porci...
Khodadad Khodadadi,Huseyin Sumer,Maryam Pashaiasl et al.
Khodadad Khodadadi et al.
Despite tremendous efforts on isolation of pluripotent equine embryonic stem (ES) cells, to date there are few reports about successful isolation of ESCs and no report of in vivo differentiation of this important companion species. We repor...
Derivation of neural progenitors and retinal pigment epithelium from common marmoset and human pluripotent stem cells [0.03%]
恒河猴和人多能干细胞向神经前体细胞和视网膜色素上皮细胞的分化
Laughing Bear Torrez,Yukie Perez,Jing Yang et al.
Laughing Bear Torrez et al.
Embryonic and induced pluripotent stem cells (IPSCs) derived from mammalian species are valuable tools for modeling human disease, including retinal degenerative eye diseases that result in visual loss. Restoration of vision has focused on ...
Stem cell and tissue engineering applications in orthopaedics and musculoskeletal medicine [0.03%]
骨科与运动医学中的干细胞和组织工程学应用
Wasim S Khan,Umile Giuseppe Longo,Adetola Adesida et al.
Wasim S Khan et al.
Andreas Schmitt,Martijn van Griensven,Andreas B Imhoff et al.
Andreas Schmitt et al.
Stem cell research plays an important role in orthopedic regenerative medicine today. Current literature provides us with promising results from animal research in the fields of bone, tendon, and cartilage repair. While early clinical resul...
Reinhold J Medina,Christina L O&#x;Neill,T Michelle O&#x;Doherty et al.
Reinhold J Medina et al.
Endothelial progenitor cells (EPCs) have great clinical value because they can be used as diagnostic biomarkers and as a cellular therapy for promoting vascular repair of ischaemic tissues. However, EPCs also have an additional research val...
Minced umbilical cord fragments as a source of cells for orthopaedic tissue engineering: an in vitro study [0.03%]
骨科组织工程细胞来源：体外研究脐带碎片与骨髓干细胞的比较
A Marmotti,S Mattia,M Bruzzone et al.
A Marmotti et al.
A promising approach for musculoskeletal repair and regeneration is mesenchymal-stem-cell- (MSC-)based tissue engineering. The aim of the study was to apply a simple protocol based on mincing the umbilical cord (UC), without removing any bl...