Nasopharyngeal carcinoma signaling pathway: an update on molecular biomarkers [0.03%]
鼻咽癌信号通路：分子生物标志物的最新研究进展
Warut Tulalamba,Tavan Janvilisri
Warut Tulalamba
Nasopharyngeal carcinoma (NPC) is an uncommon cancer, which has a distinctive ethnic and geographic distribution. Etiology of NPC is considered to be related with a complex interaction of environmental and genetic factors as well as Epstein...
Distribution of cytoskeletal components in endothelial cells in the Guinea pig renal artery [0.03%]
Guinea猪肾动脉内皮细胞骨架分布
Kazuo Katoh,Yasuko Noda
Kazuo Katoh
The cytoskeletal components of endothelial cells in the renal artery were examined by analysis of en face preparations under confocal laser scanning microscopy. Renal arterial endothelial cells were shown to be elongated along the direction...
Mita Varghese,Peter Gorsevski,Marilyn L Cayer et al.
Mita Varghese et al.
A COMPUTERIZED MORPHOMETRIC CLASSIFICATION TECHNIQUE BASED ON LATENT FACTORS REVEALS MAJOR PROTRUSION CLASSES: factors 4, 5, and 7. Previous work showed that factor 4 represented filopodia, 5 the distribution of lamellar cytoplasm, and 7 a ...
Casein kinase iγ2 impairs fibroblasts actin stress fibers formation and delays cell cycle progression in g1 [0.03%]
酪蛋白激酶iγ2干扰成纤维细胞肌动蛋白张力丝的形成并延迟G1期细胞周期进程
Mathieu Latreille,Afnan Abu-Thuraia,Rossella Oliva et al.
Mathieu Latreille et al.
Actin cytoskeleton remodeling is under the regulation of multiple proteins with various activities. Here, we demonstrate that the γ2 isoform of Casein Kinase I (CKIγ2) is part of a novel molecular path regulating the formation of actin st...
The physiological role of mitophagy: new insights into phosphorylation events [0.03%]
线粒体自噬的生理作用：磷酸化事件的新见解
Yuko Hirota,Dongchon Kang,Tomotake Kanki
Yuko Hirota
Mitochondria play an essential role in oxidative phosphorylation, fatty acid oxidation, and the regulation of apoptosis. However, this organelle also produces reactive oxygen species (ROS) that continually inflict oxidative damage on mitoch...
Hidemi Rikiishi
Hidemi Rikiishi
For several decades, apoptosis has taken center stage as the principal mechanism of programmed cell death (type I cell death) in mammalian tissues. Autophagic cell death (type II) is characterized by the massive accumulation of autophagic v...
Michal Letek,María Fiuza,Almudena F Villadangos et al.
Michal Letek et al.
Although bacteria are considered the simplest life forms, we are now slowly unraveling their cellular complexity. Surprisingly, not only do bacterial cells have a cytoskeleton but also the building blocks are not very different from the cyt...
Zackie Aktary,Manijeh Pasdar
Zackie Aktary
Plakoglobin (γ-catenin) is a member of the Armadillo family of proteins and a homolog of β-catenin. As a component of both the adherens junctions and desmosomes, plakoglobin plays a pivotal role in the regulation of cell-cell adhesion. Fu...
Reticulophagy and ribophagy: regulated degradation of protein production factories [0.03%]
网状结构自噬和核糖体自噬：蛋白合成工厂的程序性降解
Eduardo Cebollero,Fulvio Reggiori,Claudine Kraft
Eduardo Cebollero
During autophagy, cytosol, protein aggregates, and organelles are sequestered into double-membrane vesicles called autophagosomes and delivered to the lysosome/vacuole for breakdown and recycling of their basic components. In all eukaryotes...
Identification and characterization of novel perivascular adventitial cells in the whole mount mesenteric branch artery using immunofluorescent staining and scanning confocal microscopy imaging [0.03%]
免疫荧光染色和激光共聚焦显微镜技术鉴定并表征全立体结肠中动脉外膜全新血管周围细胞
Chandra Somasundaram,Rahul K Nath,Richard D Bukoski et al.
Chandra Somasundaram et al.
A novel perivascular adventitial cell termed, adventitial neuronal somata (ANNIES) expressing the neural cell adhesion molecule (NCAM) and the vasodilator neuropeptide, calcitonin gene-related peptide (CGRP), exists in the adult rat mesente...