Lina Ghibelli,Alina Grzanka
Lina Ghibelli
Formulation Changes Affect Material Properties and Cell Behavior in HA-Based Hydrogels [0.03%]
制备方法影响基于羟基磷灰石的水凝胶材料性能及细胞行为
Thomas Lawyer,Kristen McIntosh,Cristian Clavijo et al.
Thomas Lawyer et al.
To develop and optimize new scaffold materials for tissue engineering applications, it is important to understand how changes to the scaffold affect the cells that will interact with that scaffold. In this study, we used a hyaluronic acid- ...
Synergistic modulation of cellular contractility by mixed extracellular matrices [0.03%]
混合细胞外基质对细胞收缩性的协同调节作用
Aastha Kapoor,Shamik Sen
Aastha Kapoor
The extracellular matrix (ECM) is known to provide various physicochemical cues in directing cell behavior including composition, topography, and dimensionality. Physical remodeling of the ECM has been documented in a variety of cancers. In...
Redox status and bioenergetics liaison in cancer and neurodegeneration [0.03%]
癌症与神经退行性病变中的氧化还原状态和生物能量代谢关系
Giuseppe Filomeni,Juan P Bolaños,Pier Giorgio Mastroberardino
Giuseppe Filomeni
Claudia Consales,Caterina Merla,Carmela Marino et al.
Claudia Consales et al.
Electromagnetic fields (EMFs) originating both from both natural and manmade sources permeate our environment. As people are continuously exposed to EMFs in everyday life, it is a matter of great debate whether they can be harmful to human ...
Nic E Savaskan,Günter Fingerle-Rowson,Michael Buchfelder et al.
Nic E Savaskan et al.
Macrophage migration inhibitory factor (MIF) is a cytokine which also exhibits enzymatic properties like oxidoreductase and tautomerase. MIF plays a pivotal role in innate and acquired immunity as well as in the neuroendocrine axis. Since i...
Molecular Regulation of the Mitochondrial F(1)F(o)-ATPsynthase: Physiological and Pathological Significance of the Inhibitory Factor 1 (IF(1)) [0.03%]
线粒体F(1)F(o)-ATP合酶的分子调控：抑制因子1(IF(1)))的生理及病理意义
Danilo Faccenda,Michelangelo Campanella
Danilo Faccenda
In mammals, the mitochondrial F(1)F(o)-ATPsynthase sets out the energy homeostasis by producing the bulk of cellular ATP. As for every enzyme, the laws of thermodynamics command it; however, it is privileged to have a dedicated molecular re...
Redox Regulation of Protein Function via Cysteine S-Nitrosylation and Its Relevance to Neurodegenerative Diseases [0.03%]
半胱氨酸S-硝基化的蛋白质功能的氧化还原调节及其与神经退行性疾病的相关性
Mohd Waseem Akhtar,Carmen R Sunico,Tomohiro Nakamura et al.
Mohd Waseem Akhtar et al.
Debilitating neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD), can be attributed to neuronal cell damage in specific brain regions. An important hallmark of these diseases is increased oxidative and ...
Selective types of autophagy [0.03%]
选择性自噬类型
Fulvio Reggiori,Masaaki Komatsu,Kim Finley et al.
Fulvio Reggiori et al.
Established Principles and Emerging Concepts on the Interplay between Mitochondrial Physiology and S-(De)nitrosylation: Implications in Cancer and Neurodegeneration [0.03%]
线粒体生理与S-（脱）硝化作用之间相互作用的既定原理和新兴概念：癌症和神经变性中的意义
Giuseppina Di Giacomo,Salvatore Rizza,Costanza Montagna et al.
Giuseppina Di Giacomo et al.
S-nitrosylation is a posttranslational modification of cysteine residues that has been frequently indicated as potential molecular mechanism governing cell response upon redox unbalance downstream of nitric oxide (over)production. In the la...