Transmission electron microscopy studies of cellular responses to entry of virions: one kind of natural nanobiomaterial [0.03%]
细胞对病毒颗粒入侵反应的电子显微镜研究：一种天然纳米生物材料
Zheng Liu,Shuyu Liu,Jinming Cui et al.
Zheng Liu et al.
Virions are one kind of nanoscale pathogen and are able to infect living cells of animals, plants, and bacteria. The infection is an intrinsic property of the virions, and the biological process provides a good model for studying how these ...
Ioannis P Nezis
Ioannis P Nezis
Autophagy is an evolutionarily conserved process of cellular self-eating and is a major pathway for degradation of cytoplasmic material by the lysosomal machinery. Autophagy functions as a cellular response in nutrient starvation, but it is...
Implications of therapy-induced selective autophagy on tumor metabolism and survival [0.03%]
治疗诱导的选择性自噬对肿瘤代谢和存活的影响
Luke R K Hughson,Vincent I Poon,Jaeline E Spowart et al.
Luke R K Hughson et al.
Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective f...
The many faces of mitochondrial autophagy: making sense of contrasting observations in recent research [0.03%]
线粒体自噬的多种表现：近期研究中对比明显的观察结果的新见解
Alexander I May,Rodney J Devenish,Mark Prescott
Alexander I May
Research into the selective autophagic degradation of mitochondria-mitophagy-has intensified in recent years, yielding significant insights into the function, mechanism, and regulation of this process in the eukaryotic cell. However, while ...
Maria I Vaccaro
Maria I Vaccaro
Timing is everything. That's especially true when it comes to the activation of enzymes created by the pancreas to break down food. Pancreatic enzymes are packed in secretory granules as precursor molecules called zymogens. In physiological...
Clot Formation in the Sipunculid Worm Themiste petricola: A Haemostatic and Immune Cellular Response [0.03%]
Themiste petricola管状蠕虫的血栓形成：一种止血和免疫细胞反应
Tomás Lombardo,Guillermo A Blanco
Tomás Lombardo
Clot formation in the sipunculid Themiste petricola, a coelomate nonsegmented marine worm without a circulatory system, is a cellular response that creates a haemostatic mass upon activation with sea water. The mass with sealing properties ...
Paternal Benzo[a]pyrene Exposure Modulates MicroRNA Expression Patterns in the Developing Mouse Embryo [0.03%]
父本暴露于苯并[a]芘可改变小鼠胚胎发育过程中微小RNAs的表达模式
Asgeir Brevik,Birgitte Lindeman,Gunnar Brunborg et al.
Asgeir Brevik et al.
Little attention has been given to how microRNA expression is affected by environmental contaminants exposure. We investigate the effects of paternal exposure to benzo[a]pyrene (B[a]P) on miRNA expression in the developing mouse embryo. Mal...
Cell adhesion in cancer [0.03%]
癌细胞的黏附作用
Eok-Soo Oh,Motoharu Seiki,Martin Gotte et al.
Eok-Soo Oh et al.
Hidenori Otera,Katsuyoshi Mihara
Hidenori Otera
Mitochondria participate in a variety of physiologic processes, such as ATP production, lipid metabolism, iron-sulfur cluster biogenesis, and calcium buffering. The morphology of mitochondria changes dynamically due to their frequent fusion...
Christian Behrends,Simone Fulda
Christian Behrends
Autophagy has long been thought to be an essential but unselective bulk degradation pathway. However, increasing evidence suggests selective autophagosomal turnover of a broad range of substrates. Bifunctional autophagy receptors play a key...