Histopathological characterization of skin and muscle lesions induced by lionfish (Pterois volitans) venom in a murine experimental model [0.03%]
斑纹狮子鱼(Pterois volitans)毒液诱导的小鼠皮肤和肌肉病变的组织病理学特征
Cecilia Díaz,Arturo Chang-Castillo,Natalia Ortiz
Cecilia Díaz
Background: Fish venoms have been poorly characterized and the available information about their composition suggests they are uncomplicated secretions that, combined with epidermal mucus, could induce an inflammatory rea...
Phα1β interaction with the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG channel [0.03%]
人ERG通道转染的HEK293细胞中Phα1β与Kv11.1钾通道的相互作用研究
João B Calixto,Adara Aurea Dos Santos,Juliano Ferreira et al.
João B Calixto et al.
Background: This study examines the impact of Phα1β, a spider peptide derived from the venom of Phoneutria nigriventer, on the Kv11.1 potassium channel in HEK293 cells transfected with the human ERG potassium channel. P...
A systematic review of reports on aquatic envenomation: are there global hot spots and vulnerable populations? [0.03%]
关于水生动物蜇伤报告的系统评价：是否存在全球热点地区和易感人群？
Raechel Kadler,Catherine Pirkle,Angel Yanagihara
Raechel Kadler
Envenomation by aquatic species is an under-investigated source of human morbidity and mortality. Increasing population density along marine and freshwater coastlines increases these incidents. Specific occupational groups - including comme...
Spinal antinociceptive effect of the PnTx4(5-5) peptide is possibly mediated by the NMDA autoreceptors [0.03%]
PnTx4(5-5)多肽脊髓镇痛效应可能通过NMDA自身受体介导
Mariana Murta de Abreu,Nancy Scardua Binda,Marcos Paulo Ferreira Corrêa Alves Reis et al.
Mariana Murta de Abreu et al.
Background: Medications currently used to treat pain are frequently associated with serious adverse effects and rapid development of tolerance. Thus, there is a need to develop more effective, and safer medicines for the ...
Immunogenic potential and neutralizing ability of a heterologous version of the most abundant three-finger toxin from the coral snake Micrurus mipartitus [0.03%]
一种海蛇Micrurus mipartitus体内含量最丰富的三指素异源版本的免疫原性和中和能力
Luz Elena Romero Giraldo,Sergio Pulido,Mario Andrés Berrío et al.
Luz Elena Romero Giraldo et al.
Background: Micrurus mipartitus is a coral snake of public health concern in Colombia. Its venom is mainly composed of three-finger toxins (3FTxs), Mipartoxin-1 being the most abundant protein partially responsible for its lethal effect. In...
Isolation and cDNA cloning of four peptide toxins from the sea anemone Heteractis aurora [0.03%]
从海葵中分离并克隆四种肽类毒素的cDNA分子
Tomohiro Homma,Masami Ishida,Yuji Nagashima et al.
Tomohiro Homma et al.
Background: Sea anemones are well known to contain multiple peptide toxins. However, of more than 1100 species of sea anemones distributed worldwide, only a little over 50 have been studied for peptide toxins. Therefore, ...
Immunomodulatory effect of Tityus sp. in mononuclear cells extracted from the blood of rheumatoid arthritis patients [0.03%]
东帕毒蛛对类风湿关节炎患者外周血单个核细胞免疫调节作用研究
Cindy Gabriela Rivera Tobar,Yisel Del Mar Morales Urmendiz,Marcela Alejandra Vallejo et al.
Cindy Gabriela Rivera Tobar et al.
Background: Pathophysiological mechanisms of rheumatoid arthritis arise because of a proinflammatory environment, generated by the interaction of autoreactive lymphocytes and proinflammatory mediators. Current strategies ...
Human visceral leishmaniasis and polymorphisms in interleukin-coding genes: a systematic review [0.03%]
人类内脏利什曼病与白细胞介素编码基因多态性的系统评价研究
Amanda Virginia Batista Vieira,Manuela Rocha de Menezes,Pablo Cantalice Santos Farias et al.
Amanda Virginia Batista Vieira et al.
Visceral leishmaniasis (VL) is a neglected disease that is typical of tropical and subtropical parts of the world and is caused by the trypanosomatid Leishmania donovani complex. This disease is a multifactorial condition that involves para...
Prevalence of elephantiasis, an overlooked disease in Southern Africa: a comprehensive review [0.03%]
南非被忽视疾病的象皮病流行情况综合述评
Siphamandla Qhubekani Lamula,Elizabeth Bosede Aladejana,Emmanuel Adebowale Aladejana et al.
Siphamandla Qhubekani Lamula et al.
Elephantiasis, also known as lymphatic filariasis (LF), is a debilitating condition characterized by the thickening of the skin and muscles, primarily affecting the limbs, genitalia, and female breasts. Lymphatic filariasis is a major globa...
Snake venom bioprospecting as an approach to finding potential anti-glioblastoma molecules [0.03%]
蛇毒生物勘探作为寻找潜在抗胶质母细胞瘤分子的方法
Javier Orozco-Mera,Alejandro Montoya-Gómez,Daiana Silva Lopes et al.
Javier Orozco-Mera et al.
Glioblastoma (GB) is the most common type of malignant tumor of the central nervous system, responsible for significant morbidity and with a 5-year overall relative survival of only 6.8%. Without advances in treatment in the last twenty yea...