Jesús Eduardo Vega-Tamayo,Esteban de Jesús Alcantar-Orozco,Ramiro Arturo Mendoza-Ramírez et al.
Jesús Eduardo Vega-Tamayo et al.
Cnidarian venom toxins have attracted increasing interest due to their remarkable molecular diversity and pharmacological potential. Omics technologies - such as genomics, transcriptomics, proteomics, and metabolomics - have facilitated the...
Telemedicine for COVID-19 management in Brazil: outcomes and health system implications from a prospective cohort study [0.03%]
巴西COVID-19管理的远程医疗：前瞻性队列研究的结果和卫生系统的启示
Ana Silvia Sartori Barraviera Seabra Ferreira,Cassiana Mendes Bertoncelo Fontes,Lehana Thabane et al.
Ana Silvia Sartori Barraviera Seabra Ferreira et al.
Background: The COVID-19 pandemic exposed vulnerabilities in traditional disease surveillance systems, particularly in data reporting and contact tracing. Telemedicine emerged as a promising approach to expand remote acce...
Cecal appendicitis as a rare manifestation of paracoccidioidomycosis: A case report and systematic review of the literature [0.03%]
半乳病性腹膜炎罕见并发症：阑尾发炎一例报告及文献综述
Isadora de Lima Xavier Andrade,Bruna Abdul Ahad Saad,Alexandre Albuquerque Bertucci et al.
Isadora de Lima Xavier Andrade et al.
Background: Paracoccidioidomycosis (PCM) is a systemic mycosis endemic to Latin America, with the acute/subacute form predominantly affecting children and young adults. Cases of cecal appendicitis caused by Paracoccidioid...
Therapeutic potential of iron oxide nanoparticles for cutaneous leishmaniasis: a systematic review of in vitro and in viv o studies [0.03%]
铁氧化纳米颗粒治疗皮肤利什曼病的潜力：体外和体内研究的系统评价
Priscila de Cássia da Silva,Bruna de Macedo Lima,Camila Sales Nascimento et al.
Priscila de Cássia da Silva et al.
The treatment of cutaneous leishmaniasis (CL) is challenged by limited therapeutic options, high drug toxicity, and frequent treatment failure. In this context, iron oxide nanoparticles (IONPs) have emerged as promising therapeutic alternat...
Proteasome-driven modulation of immune and oxidative pathways during scorpion envenomation pathogenesis [0.03%]
蛋白酶体在蝎子蛰伤发病过程中的免疫和氧化途径的调节作用
Amal Megdad-Lamraoui,Sonia Adi-Bessalem,Fares Daachi et al.
Amal Megdad-Lamraoui et al.
Background: Scorpion venom contains a variety of toxin molecules that are the drivers of inflammation and oxidative stress, leading to significant tissue damage. While several mechanisms underlying these responses have be...
IMRC-Exo mitigates Deinagkistrodon acutus venom-induced limb injury in rabbits by inhibiting GSDME-dependent pyroptosis [0.03%]
IMRC-Exo通过抑制GSDME依赖性焦亡缓解了尖吻腹蛇毒诱导的兔肢体损伤
Haohao Wu,Lutao Xie,Wang Du et al.
Haohao Wu et al.
Background: Inflammation plays a critical role in the pathogenesis of limb injury caused by Deinagkistrodon acutus snakebite. Investigating its regulatory mechanisms and intervention strategies may help identify effective...
Phospholipase A2 from Daboia siamensis venom induces acute kidney injury: involvement of ion channels in an isolated perfused rabbit kidney model [0.03%]
眼镜王蛇毒磷脂酶A₂诱导急性肾损伤：兔灌注肾脏模型中离子通道介导的作用
Narongsak Chaiyabutr,Taksa Vasaruchapong,Panithi Laoungbua et al.
Narongsak Chaiyabutr et al.
Background: Acute kidney injury (AKI) is a serious complication associated with Daboia siamensis envenomation, primarily due to direct nephrotoxicity. This study aimed to investigate the effects of the phospholipase A2 (R...
Promucetin, a new C-type lectin-like protein modulates coagulation by activating platelets via GPIb [0.03%]
促凝蛋白promucetin通过GPIb激活血小板来调节凝血反应
Xiao-Qin Yu,Qi-Yun Zhang,Shu-Ting Zhou et al.
Xiao-Qin Yu et al.
Background: Snake venom C-type lectin-like proteins (also known as snaclecs) have anticoagulation and procoagulation effects by targeting platelet or coagulation factor IX/X, suggesting their potential as candidates for n...
Use of spheroids as a model to evaluate the anticancer action of animal venoms and derived molecules: 2010-2024 review [0.03%]
球形体作为评估动物毒液及其衍生物抗癌作用模型的使用：2010-2024年回顾
Yenny Yolanda Lozano Jiménez,Juan Daniel Hernández Vargas,David Mateo Navarrete Benavides et al.
Yenny Yolanda Lozano Jiménez et al.
Background: Cancer is one of the leading causes of death worldwide, with incidence rates continuously increasing, thereby posing a major healthcare challenge. Although many oncological drugs fulfill therapeutic requiremen...
Translational science at the undergraduate level: awakening talents to overcome the valley of death - case report [0.03%]
本科层次的转化医学：觉醒人才以跨越死亡之谷-案例报告
Rui Seabra Ferreira Jr,Cristina Kampus Mantovani,Ana Silvia Sartori Barraviera Seabra Ferreira et al.
Rui Seabra Ferreira Jr et al.
Background: In the biomedical field, translational science is the process of applying basic scientific knowledge to advance clinical research through the creation of new drugs, devices, medical procedures, preventive meas...