Nephrotoxic acute kidney injury induced by Daboia siamensis venom and its fractions: assessment of Bcl-2 family expression in in vivo and ex vivo in rabbit models [0.03%]
眼镜王蛇毒诱导急性肾损伤及分组小分子肽RBE-14对家兔的肾脏毒性作用及其机制研究
Narongsak Chaiyabutr,Sunutcha Suntrarachun,Suchitra Khunsap et al.
Narongsak Chaiyabutr et al.
Background: Envenomation by Daboia siamensis venom (RVV) can cause acute kidney injury (AKI), but its mechanisms remain unclear. Renal cell death via necrosis and apoptosis is central to AKI progression. Bax and Bcl-2 are...
Antimicrobial peptides from arthropod venoms exhibit activity against Sporothrix species [0.03%]
节肢动物毒液中的抗菌肽对Sporothrix菌株表现出活性
Maiara Campolina de Miranda,William Gustavo Lima,Izabella Christina de Castro Rodrigues et al.
Maiara Campolina de Miranda et al.
Background: Sporotrichosis is a fungal infection caused by species of the Sporothrix schenckii complex. Antifungal treatment with itraconazole and amphotericin B is limited by increasing resistance, adverse effects, and p...
Distinct pathophysiological mechanisms of Heterometrus laoticus and Lychas mucronatus scorpion venoms on cardiovascular and renal functions [0.03%]
Heterometrus laoticus和Lychas mucronatus蝎子毒液对心血管和肾脏功能的不同的病理生理机制
Narongsak Chaiyabutr,Lawan Chanhome,Panithi Laoungbua et al.
Narongsak Chaiyabutr et al.
Background: Heterometrus laoticus and Lychas mucronatus are widely distributed in Southeast Asia, yet their pathophysiological effects of both venoms remain poorly characterized due to low human fatality rates. This study...
Cerebral Aspergillus penicillioides infection mimicking schwannoma in an immunocompetent host: case report with a review of the literature [0.03%]
一例免疫功能正常的宿主Aspergillus penicillioides脑感染类似施万细胞瘤的病例报告及文献回顾
William Kazunori Sekiguchi,Juliana Possatto Fernandes Takahashi,Jessica de Brito Ferreira Nascimento et al.
William Kazunori Sekiguchi et al.
Background: Central nervous system aspergillosis is a rare and severe condition with high mortality and frequent diagnostic delay. Infection due to Aspergillus penicillioides in this setting is rarely reported. ...
A proactive multidisciplinary approach to Naja atra envenomation reduces surgical burden and length of hospital stay [0.03%]
主动的多学科方法应对中国毒蛇奈亚トラ蝮蛇咬伤，减少手术负担和缩短住院时间
Hsien-Po Huang,Ting-Kuang Yeh,Po-Hsiu Huang et al.
Hsien-Po Huang et al.
We report that the implementation of a multidisciplinary team (MDT) protocol - integrating early ultrasound surveillance, prompt surgical intervention, targeted antimicrobial therapy, and optimized antivenom administration - was associated ...
Predictive value of admission blood glucose for early severity stratification in pediatric scorpion envenomation [0.03%]
入院血糖对儿童蝎子蜇伤早期病情分层的预测价值分析
Tatiane Felícia Dos Santos,Ana Thereza Chaves Lages,Adebal Andrade et al.
Tatiane Felícia Dos Santos et al.
Background: Scorpion stings are an increasing public health concern in Brazil, where children are at a heightened risk of severe outcomes. Simple biomarkers, such as admission blood glucose may improve early risk stratifi...
A venom fraction from the Philippine tarantula (Orphnaecus sp.) reveals low-molecular-weight compounds that potentiate drug-like neurobehavioral responses in Danio rerio [0.03%]
一种来自菲律宾塔兰图拉蜘蛛（Orphnaecus.sp）的毒液组分可揭示出低分子量化合物，该化合物能增强丹尼洛氏黄杆菌的药物类似神经行为反应
Joshua Lawrence C Bautista,Elian Angelo M Abellanosa,Ralph Emerson John Molino et al.
Joshua Lawrence C Bautista et al.
Background: Spider venoms are rich natural sources of bioactive chemicals ranging from low-molecular-mass compounds to larger molecules such as low molecular mass peptides, proteins, and enzymes. Some compounds have been ...
Acute compartment syndrome in Bothrops atrox envenomation: a case-control study in the Brazilian Amazon [0.03%]
巴Atlantic森蚺 venom导致的急性 compart综合征：一项巴西 Atlantic森蚺地区病例对照研究
Glenda de Oliveira Batista do Nascimento,Débora Nery Oliveira,Talia de Oliveira Mota et al.
Glenda de Oliveira Batista do Nascimento et al.
Background: Bothrops snakebite is common in the Amazon region and can lead to severe complications in the affected limb, including secondary bacterial infections, blisters, necrosis, and acute compartment syndrome (ACS) i...
Jesús Eduardo Vega-Tamayo,Esteban de Jesús Alcantar-Orozco,Ramiro Arturo Mendoza-Ramírez et al.
Jesús Eduardo Vega-Tamayo et al.
Cnidarian venom toxins have attracted increasing interest due to their remarkable molecular diversity and pharmacological potential. Omics technologies - such as genomics, transcriptomics, proteomics, and metabolomics - have facilitated the...
Telemedicine for COVID-19 management in Brazil: outcomes and health system implications from a prospective cohort study [0.03%]
巴西COVID-19管理的远程医疗：前瞻性队列研究的结果和卫生系统的启示
Ana Silvia Sartori Barraviera Seabra Ferreira,Cassiana Mendes Bertoncelo Fontes,Lehana Thabane et al.
Ana Silvia Sartori Barraviera Seabra Ferreira et al.
Background: The COVID-19 pandemic exposed vulnerabilities in traditional disease surveillance systems, particularly in data reporting and contact tracing. Telemedicine emerged as a promising approach to expand remote acce...