Phlogiellus bundokalbo spider venom: cytotoxic fractions against human lung adenocarcinoma (A549) cells [0.03%]
邦多卡尔博蛛毒液中的细胞毒性分数对人肺腺癌(A549)细胞的影响
Anna Beatriz R Mayor,Leonardo A Guevarra Jr,Myla R Santiago-Bautista et al.
Anna Beatriz R Mayor et al.
Background: Spider venom is a potential source of pharmacologically important compounds. Previous studies on spider venoms reported the presence of bioactive molecules that possess cell-modulating activities. Despite thes...
Streamlined downstream process for efficient and sustainable (Fab')2 antivenom preparation [0.03%]
用于高效和可持续制备(Fab')2抗蛇毒血清的简化的下游工艺流程
Tihana Kurtović,Marija Brgles,Maja Lang Balija et al.
Tihana Kurtović et al.
Background: Antivenoms are the only validated treatment against snakebite envenoming. Numerous drawbacks pertaining to their availability, safety and efficacy are becoming increasingly evident due to low sustainability of...
Cytotoxic and anticancer properties of the Malaysian mangrove pit viper (Trimeresurus purpureomaculatus) venom and its disintegrin (purpureomaculin) [0.03%]
马来西亚红点白花蛇(Trimeresurus purpureomaculatus)毒液及其整合素（purpureomaculin）的细胞毒性及抗癌特性
Choo Hock Tan,Jia Lee Liew,Suerialoasan Navanesan et al.
Choo Hock Tan et al.
Background: The Asiatic pit vipers from the Trimeresurus complex are medically important venomous snakes. These pit vipers are often associated with snakebite that leads to fatal coagulopathy and tissue necrosis. The cyto...
Suppression of cardiomyocyte functions by β-CTX isolated from the Thai king cobra (Ophiophagus hannah) venom via an alternative method [0.03%]
通过替代方法从泰国王 Cobra(Ophiophagus hannah) 真空中的β- CTX 抑制心肌细胞功能
Tuchakorn Lertwanakarn,Montamas Suntravat,Elda E Sanchez et al.
Tuchakorn Lertwanakarn et al.
Background: Beta-cardiotoxin (β-CTX), the three-finger toxin isolated from king cobra (Ophiophagus hannah) venom, possesses β-blocker activity as indicated by its negative chronotropy and its binding property to both β...
Erratum: Antiproliferative activity of marine stingray Dasyatis sephen venom on human cervical carcinoma cell line [0.03%]
Erratum：刺鳐Dasyatis sephen毒素对人类宫颈癌细胞系增殖的抑制作用
[This corrects the article DOI: 10.1186/s40409-015-0036-5.].
Clinical assessment and pathophysiology of Bothrops venom-related acute kidney injury: a scoping review [0.03%]
巴西斑腹矛头 viper 毒素相关急性肾损伤的临床评估与发病机制：系统综述式回顾
Polianna Lemos Moura Moreira Albuquerque,José Hicaro Hellano Gonçalves Lima Paiva,Alice Maria Costa Martins et al.
Polianna Lemos Moura Moreira Albuquerque et al.
Bothrops are one of the most common medically important snakes found in Latin America. Its venom is predominantly hemotoxic and proteolytic, which means that local lesion (edema and redness) and hemorrhagic symptoms are recurrent in envenom...
Recombinant antibodies against Iranian cobra venom as a new emerging therapy by phage display technology [0.03%]
噬菌体展示技术用于伊朗 Cobra 毒液的重组抗体抗作为新的治疗方法
Ali Nazari,Maedeh Samianifard,Hadi Rabie et al.
Ali Nazari et al.
Background: The production of antivenom from immunized animals is an established treatment for snakebites; however, antibody phage display technology may have the capacity to delivery results more quickly and with a bette...
Toxicological effects of bioactive peptide fractions obtained from Bothrops jararaca snake venom on the structure and function of mouse seminiferous epithelium [0.03%]
巴西矛头蝮蛇蛇毒生物活性肽组分对小鼠生精上皮结构和功能的毒性作用效应研究
Carlos Alberto-Silva,Celline Sampaio Franzin,Joyce Meire Gilio et al.
Carlos Alberto-Silva et al.
Background: Pathogenesis of Bothrops envenomations is complex and despite numerous studies on the effects of this snake venom on various biological systems, relatively little is known about such effects on the male reprod...
Chronic venous ulcers: a review on treatment with fibrin sealant and prognostic advances using proteomic strategies [0.03%]
慢性静脉溃疡：用纤维蛋白密封剂治疗及蛋白质组学策略预测预后的综述研究
Luciana Patricia Fernandes Abbade,Rui Seabra Ferreira Jr,Lucilene Delazari Dos Santos et al.
Luciana Patricia Fernandes Abbade et al.
Venous ulcers are the main causes of chronic lower-limb ulcers. The healing difficulties encourage the research and development of new products in order to achieve better therapeutic results. Fibrin sealant is one of these alternatives. Bes...
Why does the number of dangerous species of scorpions increase? The particular case of the genus Leiurus Ehrenberg (Buthidae) in Africa [0.03%]
毒蝎种数为何增加？以非洲少毛族（Leiurus）少毛尾蠊为例
Wilson R Lourenço
Wilson R Lourenço
The aim of this contribution is to bring some precise information on the reasons why the number of noxious scorpion species is constantly growing. This fact is directly associated with the zoological research on the domains generally define...