Maintenance of venomous snakes in captivity for venom production at Butantan Institute from 1908 to the present: a scoping history [0.03%]
巴西布坦蓝研究所1908年至今的毒蛇饲养和毒液采集：回顾性研究
Kathleen Fernandes Grego,Samira Emanuela Maria Vieira,Jarbas Prado Vidueiros et al.
Kathleen Fernandes Grego et al.
Maintenance of snakes at Butantan Institute started in the last century, intending to produce a different antivenom serum to reduce death caused by snakebites. Through a successful campaign coordinated by Vital Brazil, farmers sent venomous...
Dehydrobufotenin extracted from the Amazonian toad Rhinella marina (Anura: Bufonidae) as a prototype molecule for the development of antiplasmodial drugs [0.03%]
一种来自亚马逊美洲牛蛙(Rhinella marina)的去氢 Bufotenin作为开发抗疟药原型分子的发展方向
Felipe Finger Banfi,Gabriela Camila Krombauer,Amanda Luisa da Fonseca et al.
Felipe Finger Banfi et al.
Background: The resistance against antimalarial drugs represents a global challenge in the fight and control of malaria. The Brazilian biodiversity can be an important tool for research and development of new medicinal pr...
Design, synthesis, and evaluation of Bothrops venom serine protease peptidic inhibitors [0.03%]
Bothrops毒液丝氨酸蛋白酶肽类抑制剂的设计、合成与评价
Gloria Maria da Silva,Daniel Henrique Berto de Souza,Karoline B Waitman et al.
Gloria Maria da Silva et al.
Background: In Central and South America, snakebite envenomation is mainly caused by Bothrops spp. snakes, whose venoms feature significant biochemical richness, including serine proteases. The available bothropic antiven...
Rodrigo Ligabue-Braun
Rodrigo Ligabue-Braun
Background: The relationship between slow loris (Nycticebus spp.) venom (BGE protein) and the major cat allergen (Fel d 1) from domestic cat (Felis catus) is known for about two decades. Along this time, evidence was accu...
Chronic kidney failure following lancehead bite envenoming: a clinical report from the Amazon region [0.03%]
巴西丛林地区金头毒蛇咬伤致慢性肾衰报告
Manuela B Pucca,Michelle V S Franco,Jilvando M Medeiros et al.
Manuela B Pucca et al.
Background: Snakebite envenoming can be a life-threatening condition, for which emergency care is essential. The Bothrops (lancehead) genus is responsible for most snakebite-related deaths and permanent loss of function i...
Effect of Bitis gabonica and Dendroaspis angusticeps snake venoms on apoptosis-related genes in human thymic epithelial cells [0.03%]
Gaboon蛇毒和黑眉眼镜蛇毒对人胸腺上皮细胞凋亡相关基因的影响
Francisc Boda,Krisztina Banfai,Kitti Garai et al.
Francisc Boda et al.
Background: Certain environmental toxins permanently damage the thymic epithelium, accelerate immune senescence and trigger secondary immune pathologies. However, the exact underlying cellular mechanisms and pathways of p...
Bothrops moojeni L-amino acid oxidase induces apoptosis and epigenetic modulation on Bcr-Abl+ cells [0.03%]
L-氨基酸氧化酶诱导Bcr-Abl阳性细胞凋亡及表观遗传调控
Sandra Mara Burin,Maira da Costa Cacemiro,Juçara Gastaldi Cominal et al.
Sandra Mara Burin et al.
Background: Resistance to apoptosis in chronic myeloid leukemia (CML) is associated with constitutive tyrosine kinase activity of the Bcr-Abl oncoprotein. The deregulated expression of apoptosis-related genes and alterati...
Acute kidney failure following severe viper envenomation: clinical, biological and ultrasonographic aspects [0.03%]
严重毒蛇咬伤后的急性肾衰竭：临床、生物学和超声检查方面的问题
Blaise Adelin Tchaou,Kofi-Mensa Savi de Tové,Charles Frédéric Tchégnonsi N&#x;Vènonfon et al.
Blaise Adelin Tchaou et al.
Background: Acute kidney injury (AKI) is a frequent complication of snakebite envenomation, which is still little known in sub-Saharan Africa. This study aims to describe the clinical, biological and ultrasonographic aspe...
Role of crotoxin in coagulation: novel insights into anticoagulant mechanisms and impairment of inflammation-induced coagulation [0.03%]
石龙子毒素在凝血中的作用：抗凝机制及抑制炎症诱导的凝血的新见解
Bruna Terada Gimenez,Gabriel Neves Cezarette,Aline de Sousa Bomfim et al.
Bruna Terada Gimenez et al.
Background: Snake venom phospholipases A2 (svPLA2) are biologically active toxins, capable of triggering and modulating a wide range of biological functions. Among the svPLA2s, crotoxin (CTX) has been in the spotlight of ...
Chicken antibodies against venom proteins of Trimeresurus stejnegeri in Taiwan [0.03%]
台湾尖吻腹蛇毒液蛋白质的鸡抗体
Chi-Hsin Lee,Chia-I Liu,Sy-Jye Leu et al.
Chi-Hsin Lee et al.
Background: The venom of bamboo vipers (Trimeresurus stejnegeri - TS), commonly found in Taiwan, contains deadly hemotoxins that cause severe envenomation. Equine-derived antivenom is a specific treatment against snakebit...