Rapid on-site detection of echinococcosis and schistosomiasis based on RPA [0.03%]
基于重组酶聚合酶 amplification 的快速现场检测棘球蚴病和血吸虫病技术
Lvbo Tian,Ying Shi,Yu Yang et al.
Lvbo Tian et al.
Background: Echinococcosis and schistosomiasis, caused by parasitic worms, pose significant threats to millions of people in the world. Rapid and effective pathogen detection and epidemic control by public health authorit...
Characterization of larval habitats of Anopheles (Nyssorhynchus) darlingi and associated species in malaria areas in western Brazilian Amazon [0.03%]
巴西西部亚马逊地区疟疾流行区安第斯达灵蚊及其关联种类的幼虫栖息地特征分析
Fátima Dos Santos,Mingrui Xu,Lelys Bravo de Guenni et al.
Fátima Dos Santos et al.
Background: Anopheles darlingi is the most efficient vector of malaria parasites in the Neotropics. Nevertheless, the specificities of its larval habitats are still poorly known. ...
Advances in the development of new vaccines for tuberculosis and Brazil's role in the effort forward the end TB strategy [0.03%]
新型结核病疫苗研发进展及巴西在终结结核病战略中的角色
Ana Paula Junqueira-Kipnis,Luciana Cesar de Cerqueira Leite,Júlio Croda et al.
Ana Paula Junqueira-Kipnis et al.
Tuberculosis (TB) continues to be the world's leading killer of infectious diseases. Despite global efforts to gradually reduce the number of annual deaths and the incidence of this disease, the coronavirus disease 19 (COVID-19) pandemic ca...
Point-of-care testing for COVID-19: a simple two-step molecular diagnostic development and validation during the SARS-CoV-2 pandemic [0.03%]
《在SARS-CoV-2大流行期间开发和验证用于COVID-19的POCT简易两步分子诊断方法》
Andre Akira Gonzaga Yoshikawa,Sabrina Fernandes Cardoso,Lívia Budziarek Eslabão et al.
Andre Akira Gonzaga Yoshikawa et al.
Background: During the coronavirus disease 19 (COVID-19) pandemic, diagnostic testing of the general population proved challenging due to limitations of the gold-standard diagnostic procedure using reverse transcription r...
Overview of extracellular vesicles in pathogens with special focus on human extracellular protozoan parasites [0.03%]
病原体的细胞外囊泡概述特别关注人类细胞外原生寄生虫
Johan Alvarado-Ocampo,Elizabeth Abrahams-Sandí,Lissette Retana-Moreira
Johan Alvarado-Ocampo
Extracellular vesicles (EVs) are lipid-bilayered membrane-delimited particles secreted by almost any cell type, involved in different functions according to the cell of origin and its state. From these, cell to cell communication, pathogen-...
Description of the new HIV-1 intersubtype B/C circulating recombinant form (CRF146_BC) detected in Brazil [0.03%]
在巴西发现新型HIV-1流行重组型BC间亚型(B/C)(CRF146_BC)的描述
Rodrigo Cunha Oliveira,Darren Martin,Juliana Sacramento Mota de Souza et al.
Rodrigo Cunha Oliveira et al.
Background: The human immunodeficiency virus 1 (HIV-1) infections in Brazil are predominantly caused by two subtypes, B and C. Objectives: ...
Climate change-induced degradation of expert range maps drawn for kissing bugs (Hemiptera: Reduviidae) and long-standing current and future sampling gaps across the Americas [0.03%]
气候变化诱发的亲吻虫（半翅目：红娘华蛛科）专家分布图退化及长期存在的美洲当前和未来采集空白区分析
Vaughn Shirey,Jorge Rabinovich
Vaughn Shirey
Background: Kissing bugs are the vectors of Trypanosoma cruzi, the etiological agent of Chagas disease (CD). Despite their epidemiological relevance, kissing bug species are under sampled in terms of their diversity and i...
HIV-1 controllers exhibit an enhanced antiretroviral innate state characterised by overexpression of p21 and MCPIP1 and silencing of ERVK-6 RNA expression [0.03%]
HIV-1 控制者表现出增强的抗逆转录病毒先天状态，表现为 p21 和 MCPIP1 过表达和 ERVK-6 RNA 表达沉默
Suwellen Sardinha Dias de Azevedo,Marcelo Ribeiro-Alves,Fernanda Heloise Côrtes et al.
Suwellen Sardinha Dias de Azevedo et al.
Background: Human immunodeficiency virus (HIV)-1 infection can activate the expression of human endogenous retroviruses (HERVs), particularly HERV-K (HML-2). HIV controllers (HICs) are rare people living with HIV (PLWHs) ...
PPE59 antibodies in tuberculous patients and potential use for diagnosis when assayed with other rapid biomarkers [0.03%]
结核病患者中PPE59抗体的检测及其与其他快速生物标志物联合检测的诊断潜力
Ana Carla de Paulo Mulinari,Isabela Gama Sardella,Vania Maria C da Silva et al.
Ana Carla de Paulo Mulinari et al.
Background: PPE 59, which is absent from bacillus Calmette Guérin (BCG) strains, seems to induce a humoral immune response in patients with tuberculosis (TB). Additional studies are needed to better evaluate this protein...
Homologous equivalence study of immunogenicity after third dose of Covid-19 vaccine (recombinant) with an interval of six months after the second dose, comparing the interval of eight and 12 weeks between the first two doses [0.03%]
第三剂重组新型冠状病毒疫苗（CHO细胞）与第二剂间隔6个月，首次相邻两剂间隔4周和12周时的免疫原性序贯性研究
Clarice Monteiro Vianna,Gloria Regina da Silva E Sá,Maria Vitória Hadland Seid et al.
Clarice Monteiro Vianna et al.
Background: In response to the coronavirus disease 2019 (Covid-19) pandemic, Brazil authorised the Astra Zeneca/Fiocruz vaccine in January 2021. As the Delta variant emerged in May 2021, interval between vaccine doses was...