Role of the epitranscriptome in viral infections: beneficial or detrimental? [0.03%]
表观转录组在病毒感染中发挥有益或有害的作用？
Muhammad Fawwaz Abdullah,Kok Sing Yee,Nurhafiza Zainal et al.
Muhammad Fawwaz Abdullah et al.
Epitranscriptomics, the study of post-transcriptional chemical base modifications of RNAs, has become a crucial area of research for understanding the complex interactions between viruses and their hosts. These RNA modifications significant...
The impact of probiotic administration in vivo on peritoneal mouse macrophages infected by Leishmania amazonensis ex vivo [0.03%]
活体给药益生菌对亚马逊利什曼原虫体外感染小鼠腹腔巨噬细胞的影响
Lauren Van den Broeck,Raquel Silva de Azevedo,Ludmila Ferreira de Almeida Fiuza et al.
Lauren Van den Broeck et al.
Background: The microbiome is fundamental in the host's immunobiology and dysbiosis leads to pathological conditions, potentially affecting parasitic diseases. ...
Phospholipids and phospholipase A1 as antigens during the course of experimental Trypanosoma cruzi infection [0.03%]
实验性克休斯吉恩氏鞭毛虫感染过程中之抗原磷脂与磷脂酶A1
Emanuel Bott,Sebastián Andrés López,Guadalupe Gimenez et al.
Emanuel Bott et al.
Background: Trypanosoma cruzi, causative agent of Chagas disease (CD), remains a public health problem in Latin America and is emerging in non-endemic areas. Phospholipids (PL) are essential components of biomembranes and...
Concomitant use of anti-leishmanial therapy and antibacterial prophylaxis reduces plasma LPS levels and improves several aspects of experimental Leishmania infantum infection in golden hamsters [0.03%]
抗利什曼病药物与抗生素的联合使用可降低白细胞内LPS水平并改善金仓鼠实验性婴儿利什曼病感染的若干方面状况
Joanna Reis Santos-Oliveira,Maria Luciana Silva-Freitas,Marcelle da Senhora Cappato et al.
Joanna Reis Santos-Oliveira et al.
Background: Parasite antigens and plasma lipopolysaccharide (LPS) levels from luminal origin in visceral leishmaniasis (VL) patients are correlated with cellular activation and low CD4+T cell counts. ...
Adeilton Alves Brandão,Ana Carolina P Vicente
Adeilton Alves Brandão
Beyond the first case of Chagas disease: the Berenice strain as a model for understanding long-term Trypanosoma cruzi infection [0.03%]
首例恰加斯病之后：Berenice株作为理解长期感染的模式菌株
Diana Bahia,André Guilherme da Costa-Martins,Werica Bernardo Pereira et al.
Diana Bahia et al.
Here, we review the key findings on the genetic characterisation of Berenice strains of Trypanosoma cruzi isolated from a 2-year-old child, Berenice, the first patient with Chagas disease described in the literature in 1909. Be-62 and Be-78...
Population structure of Anopheles (Kerteszia) bellator in the Brazilian Atlantic Forest [0.03%]
巴西大西洋森林中刺扰阿纳菲勒夏蚊的种群结构
Iara Carolini Pinheiro,Kamila Voges,Andre Akira Gonzaga Yoshikawa et al.
Iara Carolini Pinheiro et al.
Background: Malaria, caused by protozoa of the genus Plasmodium and transmitted by Anopheles mosquitoes, remains a significant global health concern. In 2022, approximately 249 million malaria cases were reported worldwid...
Chagas disease in Brazil: new challenges and perspectives for old problems [0.03%]
巴西的恰加斯病：解决老问题的新挑战和展望
Fred Luciano Neves Santos,Veruska Maia da Costa,Rafaella Albuquerque E Silva
Fred Luciano Neves Santos
Mandatory notification of chronic Chagas disease (CD) is vital for improving public health responses in Brazil, where millions are affected. Implemented nationally in 2020 and supported by the "e-SUS Notifica" platform in 2023, this system ...
A 20-month longitudinal study to evaluate humoral and cellular immunity after COVID-19 vaccines [0.03%]
一项关于新冠疫苗接种后免疫反应的纵向研究报告：长达20个月的抗体及细胞免疫评估研究
Wlademir Braga Salgado Sobrinho,Bárbara Batista Salgado,Aguyda Rayany Cavalcante Barbosa et al.
Wlademir Braga Salgado Sobrinho et al.
Background: The effectiveness of coronavirus disease 2019 (COVID-19) vaccines is well established; however, the long-term durability of vaccine-induced immunity remains to be fully elucidated. ...
Susceptibility of Aedes aegypti to spinosad larvicide and space spray adulticides in Brazil [0.03%]
巴西埃及伊蚊对苏云金芽孢杆菌昆虫毒蛋白和空间喷洒成人剂的敏感性研究
Luciana Dos Santos Dias,Ademir Jesus Martins,Cynara de Melo Rodovalho et al.
Luciana Dos Santos Dias et al.
Background: Insecticides play a critical role in controlling insect vectors, particularly during epidemics. Effective chemical control relies on the robust monitoring of insecticide resistance to guide evidence-based deci...