Revisiting the development of Trypanosoma rangeli in the vertebrate host [0.03%]
重新审视锥虫Trypanosoma rangeli在脊椎动物宿主体内的发育过程
Luan Felipe Santos,Flávia de Souza Rocha,Marcelo Gustavo Lorenzo et al.
Luan Felipe Santos et al.
Background: Trypanosoma rangeli is a haemoflagellate parasite that infects triatomine bugs and mammals in South and Central America. Trypanosoma cruzi, the etiological agent of Chagas disease, has a partially overlapping ...
Plants of the family Lamiaceae as a source of therapeutic agents against Acanthamoeba infections [0.03%]
唇形科植物作为治疗阿卡纳巴菌感染药物的来源
Martin Mrva,Lucia Malíková,Mária Garajová
Martin Mrva
Background: Acanthamoebae are causative agents of severe and complicated human infections without a standard effective therapy to date. Therefore, the research is focused on the development of new amoebicidal drugs based ...
Investigating the distribution of a rare Colombo-Venezuelan kissing bug, Rhodnius neivai, Lent, 1953, using geographical information system-based analyses [0.03%]
基于地理信息系统分析调查一种罕见的科尔巴-委内瑞拉接吻虫Rhodnius neivai的分布情况
Guilherme Sanches Corrêa-do-Nascimento,Cleber Galvão,Gustavo Rocha Leite
Guilherme Sanches Corrêa-do-Nascimento
Background: Rhodnius neivai, a kissing bug found in the dry regions of Colombia and Venezuela, has limited documented occurrences. While it is not deemed a significant vector for Chagas disease, distributional and ecologi...
First comparative genomics analysis of Corynebacterium auriscanis [0.03%]
Corynebacterium auriscanis的首次比较基因组分析
Ana Lua de Oliveira Vinhal,Max Roberto Batista de Araújo,Evandro Bento Rodrigues et al.
Ana Lua de Oliveira Vinhal et al.
Background: Corynebacterium auriscanis is a bacterial species frequently isolated from dogs with external otitis or dermatitis and a zoonotic pathogen transmitted by dog bite. It is considered an opportunistic pathogen, b...
Comparative Study
Memorias do Instituto Oswaldo Cruz. 2024 Oct 25:119:e240156. DOI:10.1590/0074-02760240156 2024
The Oxente Chagas Bahia Project: evaluating the efficacy of a rapid diagnostic test and treatments for Chagas disease [0.03%]
奥克森特查加斯巴哈项目：评估一种快速诊断试验及查加斯病治疗方法的效果
Fred Luciano Neves Santos,Tycha Bianca Sabaini Pavan,Cristiane Siqueira Valle et al.
Fred Luciano Neves Santos et al.
Chagas disease (CD), caused by Trypanosoma cruzi, is a life-threatening neglected anthropozoonosis primarily transmitted by triatomine bugs. Affecting an estimated 5.7 million people globally, CD has significant morbidity and mortality, par...
Epoxy-a-lapachone in nanosystem: a prototype drug for leishmaniasis assessed in the binomial BALB/c - Leishmania (Leishmania) amazonensis [0.03%]
纳米系统中的环氧底阿帕奇酮：在BALB / c小鼠和亚马逊利什曼原虫二元组中评估的原型药物
Juliana Figueiredo Peixoto,Luiz Filipe Gonçalves-Oliveira,Geovane Dias-Lopes et al.
Juliana Figueiredo Peixoto et al.
This perspective presents and supports arguments for a new formulation of epoxy-α-lapachone loaded microemulsion (ELAP-ME), a nanosystem, as a prototype drug for the treatment of leishmaniasis. The benefits of ELAP as a multitarget compoun...
HSV1-induced enhancement of productive HIV-1 replication is associated with interferon pathway downregulation in human macrophages [0.03%]
人巨细胞中HSV1诱导的高效HIV-1复制与干扰素途径下调有关
Viviane M Andrade,Filipe Pereira-Dutra,Juliana L Abrantes et al.
Viviane M Andrade et al.
Background: Herpesviruses are common co-pathogens in individuals infected with human immunodeficiency virus (HIV). Herpes simplex virus type 1 (HSV1) enhances HIV-1 replication and has evolved mechanisms to evade or disru...
Multiplex PCR assays developed for neglected pathogen detection in undifferentiated acute febrile illness cases in tropical regions [0.03%]
针对热带地区未分化急性发热病例的多重PCR检测方法开发用于检测被忽视的病原体
Leidi Carvajal Aristizabal,Karl Ciuoderis,Laura S Pérez-Restrepo et al.
Leidi Carvajal Aristizabal et al.
Background: Undifferentiated acute febrile illness (UAFI) cause by several pathogens poses a diagnostic challenge due to the similarity on the clinical manifestations across these diseases. Precise pathogen detection is v...
Detached epithelial cell plugs from the upper respiratory tract favour distal lung injury in Golden Syrian hamsters (Mesocricetus auratus) when experimentally infected with the A.2 Brazilian SARS-CoV-2 strain [0.03%]
巴西A.2型新冠病毒感染实验中，上呼吸道脱落的上皮细胞栓子可加重金仓鼠远端肺损伤
Marcelo Pelajo-Machado,Alexandre Dos Santos da Silva,Daniela Del Rosario Flores Rodrigues et al.
Marcelo Pelajo-Machado et al.
Background: The Golden Syrian hamster (Mesocricetus auratus), Ferrets (Mustela putorius furo), and macaques have been described as useful laboratory animals naturally susceptible to severe acute respiratory syndrome coron...
First concrete documentation for presence of Aedes (Stegomyia) albopictus in Bolivia: dispelling previous anecdotes [0.03%]
玻利维亚首次发现白点伊蚊(Aedes(albopictus): Stegomyia albopicta)文献记录：纠正之前传闻说法
Frédéric Lardeux,Philippe Boussès,Rosenka Tejerina-Lardeux et al.
Frédéric Lardeux et al.
Background: The presence of Aedes albopictus in Bolivia has been a subject of controversy, with a lack of concrete documentation. Objectives: ...