Orthoflavivirus nilense surveillance in the State of Piauí, northeastern Brazil [0.03%]
巴西东北部皮奥伊州尼伦塞正黏液病毒的监测
Osmaikon Lisboa Lobato,Tayná da Silva Nogueira,Tobias Emílio Tavares Lima et al.
Osmaikon Lisboa Lobato et al.
Background: The cycle of the Orthoflavivirus nilense (West Nile virus - WNV) involves birds and mosquitoes, while humans and equids serve as terminal hosts. In 2014, the first human case in Brazil was confirmed in Piauí ...
Juliana Godoy,Igor Avellar-Moura,Juliana Soares et al.
Juliana Godoy et al.
Background: Titan cells in Cryptococcus species play a critical role in fungal virulence by resisting oxidative stress, phagocytosis, and antifungal treatments. Developing reliable methods to induce titan cells is crucial...
Identification of polymorphisms associated with attenuation of Vif and Vpr in HIV-1 Elite Controllers [0.03%]
精英控制器中与HIV-1 Vif和Vpr减弱相关的多态性鉴定
Suwellen Sardinha Dias de Azevedo,Fernanda Heloise Côrtes,Mariza G Morgado et al.
Suwellen Sardinha Dias de Azevedo et al.
Background: Elite controllers (ECs) are a rare subset of individuals who naturally suppress human immunodeficiency virus type 1 (HIV-1) replication in the absence of antiretroviral therapy. Specific polymorphisms in the a...
Genome characterisation of the first isolate of human enterovirus c99 from an acute flaccid paralysis case in Brazil [0.03%]
巴西急性无力性麻痹病例中的人类肠道病毒C99首株基因序列特征分析
Jéssica Tatiane Sauthier,Jéssica Barreto Dias,Cristiane de Sousa Ferreira et al.
Jéssica Tatiane Sauthier et al.
Background: Human enterovirus C99 (HEV-C99) is a member of the species Enterovirus C. Currently, three complete genomes of HEV-C99 were reported in Brazil, all obtained from children with gastroenteritis symptoms. Notwith...
Trichophyton rubrum inhibits Candida albicans filamentation and its gene expression when grown in biofilms in vitro [0.03%]
体外表皮癣菌抑制白色念珠菌菌落中丝状化及基因表达
Níura Madalena Bila,Carolina Orlando Vaso,Jenyffie Araújo Belizário et al.
Níura Madalena Bila et al.
Background: Dermatomycoses are caused by various fungi, including dermatophytes and Candida species, which are the most prevalent in isolated or associated forms. A great number of virulence factors expressed by these fun...
A multicentre comparative study of serological methods for diagnosing Chagas disease in Brazil [0.03%]
巴西恰加斯病血清学诊断方法的多中心比较研究
Alejandro Luquetti Ostermayer,Fernanda Alvarenga Cardoso Medeiros,Jacqueline Araújo Domingos Iturra et al.
Alejandro Luquetti Ostermayer et al.
Background: Chagas disease (CD), a neglected tropical disease caused by Trypanosoma cruzi, remains a significant often underdiagnosed public health challenge in endemic regions, affecting millions globally. Accurate and t...
Comparative Study
Memorias do Instituto Oswaldo Cruz. 2025 Jun 13:120:e240282. DOI:10.1590/0074-02760240282 2025
Assessing the spatial influence of deforestation on malaria incidence in Pará State, Amazon region, Brazil, 2008-2019 [0.03%]
2008-2019年巴西亚马逊地区的帕拉州森林砍伐对疟疾病例空间影响的评估
Carla Gisele Ribeiro Garcia,Beatriz C Ribeiro,Alcinês S Souza Júnior et al.
Carla Gisele Ribeiro Garcia et al.
Background: Malaria transmission is prevalent in tropical regions and is heavily influenced by environmental factors such as deforestation, which is particularly significant in the Brazilian Amazon, especially in Pará St...
Prevalence of pfhrp2/pfhrp3 gene deletions among patients with Plasmodium falciparum malaria with false-negative in the HRP2-based rapid diagnostic test in Colombia [0.03%]
在哥伦比亚HRP2为基础的疟疾快速检测试验假阴性恶性疟患者中pfhrp2/pfhrp3基因缺失流行情况调查
Mario Javier Olivera,Angela Patricia Guerra,Liliana Jazmín Cortés et al.
Mario Javier Olivera et al.
Background: In malaria-endemic regions, rapid diagnostic tests (RDTs) play a crucial role in promptly identifying infections, especially in remote areas with limited microscopy services. ...
Multicenter Study
Memorias do Instituto Oswaldo Cruz. 2025 Jun 13:120:e240134. DOI:10.1590/0074-02760240134 2025
X-linked polymorphisms in TLR7 and TLR8 genes are associated with protection against Chikungunya fever [0.03%]
TLR7和TLR8基因的X连锁多态性与噬咬热抗性相关
Wilker Jose Perez Gotay,Mariella Sousa Coêlho Maciel,Raphael de Oliveira Rodrigues et al.
Wilker Jose Perez Gotay et al.
Background: Chikungunya virus (CHIKV) causes an infection that leads to the activation of the innate immune response, triggering receptor pathways such as toll-like receptors (TLRs). ...
Gabriela Sadigurschi,Maria Cristina Caetano Kuschnir,Ewerton Alves Portela Dos Santos et al.
Gabriela Sadigurschi et al.
Tuberculosis (TB) is a preventable and curable disease caused by the bacillus Mycobacterium tuberculosis. In 2022, according to the World Health Organisation (WHO), TB was the second leading cause of death worldwide caused by a single infec...