Effect of Compound Danshen Dripping Pills on cardiac function after acute anterior ST-segment elevation myocardial infarction: A randomized trial [0.03%]
复方丹参滴丸对急性前壁ST段抬高心肌梗死患者心脏功能的影响：随机对照试验
Bo Deng,Sibo Wang,Yujie Wu et al.
Bo Deng et al.
The current study aimed to evaluate the efficacy and safety of Compound Danshen Dripping Pills (CDDP) in improving cardiac function among patients with acute anterior ST-segment elevation myocardial infarction (AAMI). Between February 2021 ...
Prophylactic cranial irradiation in small cell lung cancer: A review of evidence [0.03%]
小细胞肺癌预防性全脑照射的证据回顾
Femi Williams Adeoye
Femi Williams Adeoye
Hepatic SIRT6 protects against cholestatic liver disease primarily via inhibiting bile acid synthesis [0.03%]
肝SIRT6通过抑制胆汁酸合成主要保护机体免受胆汁淤积性肝病的侵害
Wen Zhang,Jiahui Wang,Luyao Yang et al.
Wen Zhang et al.
Cholestatic liver disease, caused by the accumulation of hazardous bile acids in the liver, may result in cirrhosis, fibrosis, or liver failure. Activation of SIRT6 prevents cholestasis-associated pathological events, such as oxidative stre...
Metabolic profiling identifies potential biomarkers associated with progression from gestational diabetes mellitus to prediabetes postpartum [0.03%]
代谢轮廓分析确定了可能的生物标志物与产后从妊娠糖尿病到糖尿病前期进展有关
Lenan Liu,Qian Yang,Panyuan Shen et al.
Lenan Liu et al.
The current study aims to identify potential metabolic biomarkers that predict the progression to prediabetes in women with a history of gestational diabetes mellitus (GDM). We constructed a prediabetes group ( n = 42) and a control group (...
AdipoR1 promotes pathogenic Th17 differentiation by regulating mitochondrial function through FUNDC1 [0.03%]
脂联素受体AdipoR1通过FUNDC1调节线粒体功能促进病理性Th17细胞分化
Hui Wang,Qian Zhang,Yuankai Sun et al.
Hui Wang et al.
Adiponectin receptor 1 ( Adipor1) deficiency has been shown to inhibit Th17 cell differentiation and reduce joint inflammation and bone erosion in antigen-induced arthritis (AIA) mice. Additional emerging evidence indicates that Th17 cells ...
The role of amino acids in skeletal muscle health and sarcopenia: A narrative review [0.03%]
氨基酸在骨骼肌健康和肌肉减少症中的作用：叙述性综述
Ramendu Hom Chaudhuri
Ramendu Hom Chaudhuri
The skeletal muscle is the largest organ present inside the body and is responsible for mechanical activities like maintaining posture, movement, respiratory function, and support for the health and functioning of other systems of the body....
Palmitoylethanolamide, an endogenous fatty acid amide, and its pleiotropic health benefits: A narrative review [0.03%]
棕榈乙醇胺，一种内源性脂肪酸酰胺及其多效健康益处：叙述性综述
Debasis Basu
Debasis Basu
The global nutritional transition has led to high frequency and severity of chronic degenerative diseases worldwide, primarily driven by chronic inflammatory stress. At the mealtimes, various pharmaceutical products aim to prevent such an i...
Study of the mass balance, biotransformation, and safety of [ 14C]IBI351 in healthy Chinese subjects [0.03%]
关于艾美赛珠单抗（IBI351）放射性碳-14标记的药物动力学、生物转化及安全性在中国成年受试者中的桥接研究
Shuaishuai Wang,Wen Lin,Bilal Ahmed et al.
Shuaishuai Wang et al.
IBI351, a synthetic compound, exerts its anti-tumor effects by specifically, covalently, and irreversibly modifying the 12th cysteine residue of KRAS G12C. However, the pharmacokinetic characteristics of IBI351 in the human body have not be...
LncRNA LINC01503 promotes angiogenesis in colorectal cancer by regulating VEGFA expression via miR-342-3p and HSP60 binding [0.03%]
长链非编码RNA LINC01503通过调节miR-342-3p和HSP60结合调控血管内皮生长因子A表达促进结直肠癌血管生成
Dandan Zheng,Xiya Zhang,Jia Xu et al.
Dandan Zheng et al.
Colorectal cancer (CRC) ranks among the top five most common malignant tumors worldwide and has a high mortality rate. Angiogenesis plays an important role in CRC progression; however, anti-angiogenesis therapy still has many limitations. L...
Anlotinib reverses osimertinib resistance via inhibiting epithelial-to-mesenchymal transition and angiogenesis in non-small cell lung cancer [0.03%]
安罗替尼通过抑制上皮间质转化及血管生成逆转非小细胞肺癌奥希替尼耐药性
Liting Lv,Xin Hua,Jiaxin Liu et al.
Liting Lv et al.
In the present, we aimed to investigate the effect of anlotinib on the potential reversal of osimertinib resistance by inhibiting the formation of epithelial-to-mesenchymal transition (EMT) and angiogenesis. In a clinical case, anlotinib re...