Evaluation of the plasma antioxidant activity in women with early pregnancy losses [0.03%]
评估早期妊娠丢失女性血浆抗氧化活性
Olga Gennadievna Tishkova,Lydmila Vasilievna Dikareva,Nadezhda Titovna Berberova et al.
Olga Gennadievna Tishkova et al.
Washed microbiota transplantation for ribotype 027 Clostridioides difficile infection in a pregnant woman with two-year follow-up: a case report [0.03%]
一例孕妇难辨梭状芽胞杆菌027型感染采用洗涤菌群移植治疗的两年随访病例报告
Xinyi He,Sibusiso Luthuli,Quan Wen et al.
Xinyi He et al.
Clostridioides difficile ( C. difficile) is one of the major causes of nosocomial infections. The pregnant women, who were considered at low risk for C. difficile infection (CDI), have attracted attention with increasing reports. Oral vanco...
Integrative omics and multi-cohort identify IRF1 and biological targets related to sepsis-associated acute respiratory distress syndrome [0.03%]
整合Omics和多队列鉴定与脓毒症相关性急性呼吸窘迫综合征相关的IRF1和生物靶点
Jiajin Chen,Ruili Hou,Xiaowen Xu et al.
Jiajin Chen et al.
Interferon-related genes are involved in antiviral responses, inflammation, and immunity, which are closely related to sepsis-associated acute respiratory distress syndrome (ARDS). We analyzed 1972 participants with genotype data and 681 wi...
Homoharringtonine exerts anti-silicosis potential by inhibiting the CCR1 and PI3K/AKT signaling pathways in lung fibroblasts [0.03%]
同环箭毒碱通过抑制肺成纤维细胞中的CCR1和PI3K / AKT信号通路发挥抗硅肺潜能
Xinying Jia,Ziwei Li,Xiyue Hu et al.
Xinying Jia et al.
Silicosis is an occupational lung disease caused by prolonged exposure to silica dust in the workplace. It has a complex pathogenesis and currently lacks effective treatments. Homoharringtonine(HHT), a natural compound approved for the trea...
1-year outcomes of single bolus r-SAK before primary PCI for STEMI: The follow-up of OPTIMA-5 [0.03%]
替罗非班单次注射方案用于急性ST段抬高心肌梗死急诊PCI术的1年临床预后：OPTIMA-5研究随访结果
Chen Li,Jie Yu,Tian Wu et al.
Chen Li et al.
The OPTIMA-5 study demonstrated that a single bolus of half-dose recombinant staphylokinase (r-SAK) before primary percutaneous coronary intervention (PCI) significantly improved the patency of infarct related artery in patients with ST-ele...
Using higher cut-off values to diagnose acute myocardial infarction in patients with elevated hs-cTnT [0.03%]
使用较高截断值诊断高敏cTnT升高的急性心肌梗死患者
Tian Wu,Jiaqi Chai,Chunyue Tan et al.
Tian Wu et al.
It is often challenging to diagnose acute myocardial infarction (AMI) in patients with elevated high-sensitivity cardiac troponin T (hs-cTnT) before a significant rise and/or fall of hs-cTnT can be observed. This study aimed to find an opti...
Di Pi,Shuifang Lei,Wenjing Chang et al.
Di Pi et al.
Prenatal maternal psychological distress, particularly depression, has been increasingly recognized as a factor influencing fetal growth; however, its impact on early childhood development remains less well understood. This study investigat...
OSBPL2 deficiency inhibits Rho/ROCK2/p-ERM signaling and impairs actin cytoskeletal regulation in auditory cells [0.03%]
OSBPL2缺乏抑制听觉细胞中的Rho/ROCK2/p-ERM信号并影响肌动蛋白细胞质骨架的调节
Cheng Zhang,Qian Yang,Yajie Lu et al.
Cheng Zhang et al.
Mutation in oxysterol-binding protein-like 2 ( OSBPL2) has been identified as the genetic cause of autosomal dominant nonsyndromic hearing loss (DFNA67, OMIM No. 616340). However, the pathogenesis of the OSBPL2 mutation in DFNA remains uncl...
Identification of biomarkers of male infertility through the circRNA expression profiling of seminal plasma [0.03%]
通过精浆circRNA表达谱鉴定男性不育生物标志物
Zhaode Liu,Xinrui Li,Xiaoyu Yang et al.
Zhaode Liu et al.
Circular RNAs (circRNAs) are key regulators of reproductive biology. However, limited information is available regarding circRNA expression profiles in seminal plasma samples from individuals with male infertility. The present study aimed t...
Washed microbiota transplantation effectively treats a case of acute severe ulcerative colitis combined with viral myocarditis [0.03%]
洗涤菌群移植有效治疗急性重症溃疡性结肠炎合并病毒性心肌炎1例
Rujun Ai,Yan Jin,Faming Zhang et al.
Rujun Ai et al.
Viral myocarditis is a rare but life-threatening complication in patients with ulcerative colitis (UC). Management of myocarditis is primarily supportive, as there are currently no established targeted therapies. Recent studies have increas...