The potential of carcinoembryonic antigen, p53, Ki-67 and glutathion Stransferase-π as clinico-histopathological markers for colorectal cancer [0.03%]
癌胚抗原、p53、Ki-67和谷光甘肽S转移酶-p在结直肠癌中的临床组织病理标志物价值的研究进展
Zhenyu He,Chuanbing Shi,Hao Wen et al.
Zhenyu He et al.
Objective: Colorectal cancer is one of the major contributors to cancer death worldwide. Lack of reliable colorectal cancer markers has hampered the management of these cancer patients. Our main purpose was to study the c...
The remedial effect of soluble interleukin-1 receptor type II on endometriosis in the nude mouse model [0.03%]
可溶型IL-1受体拮抗素治疗裸鼠子宫内膜异位症的疗效研究
Liying Gao,Liang Sun,Yugui Cui et al.
Liying Gao et al.
Objective: Recent studies have shown that the local expression of soluble interleukin (IL) -1 receptor type II (sIL-1 RII) in endometrial tissue of women with endometriosis is decreased, and the depression of IL-1 RII was...
Prediction of candidate small non-coding RNAs in Agrobacterium by computational analysis [0.03%]
计算分析预测植物致病菌冠瘿华杆菌中的小非编码RNA候选基因
Tingting Zhao,Ren Zhang,Mingbo Wang
Tingting Zhao
Small non-coding RNAs with important regulatory roles are not confined to eukaryotes. Recent work has uncovered a growing number of bacterial small RNAs (sRNAs), some of which have been shown to regulate critical cellular processes. Computa...
The preparation and characterization of folate-conjugated human serum albumin magnetic cisplatin nanoparticles [0.03%]
叶酸偶联的人血清白蛋白磁性顺铂纳米粒的制备及表征
Daozhen Chen,Qiusha Tang,Wenqun Xue et al.
Daozhen Chen et al.
Objective: Nanoparticles are becoming an important method of targeted drug delivery. To evaluate the importance of folate-conjugated human serum albumin (HSA) magnetic nanoparticles (Folate-CDDP/HSA MNP), we prepared drug...
Joshua M Mutiso,John C Macharia,Michael M Gicheru
Joshua M Mutiso
Over the last decade, there has been a flurry of research on adjuvants for vaccines, and several novel adjuvants are now licensed products or in late stage clinical development. The success of adjuvants in enhancing the immune response to a...
Emerging roles of cardiolipin remodeling in mitochondrial dysfunction associated with diabetes, obesity, and cardiovascular diseases [0.03%]
心磷脂重塑在糖尿病、肥胖和心血管疾病相关线粒体功能障碍中的作用不容忽视
Yuguang Shi
Yuguang Shi
Cardiolipin (CL) is a phospholipid exclusively localized in inner mitochondrial membrane where it is required for oxidative phosphorylation, ATP synthesis, and mitochondrial bioenergetics. The biological functions of CL are thought to depen...
Zhigang He
Zhigang He
Spinal cord injury disrupts the connections between the brain and spinal cord, often resulting in the loss of sensory and motor function below the lesion site. The most important reason for such permanent functional deficits is the failure ...
Gordon J Leitch,Qing He
Gordon J Leitch
Apicomplexan protozoan parasites of the genus Cryptosporidium infect the gastrointestinal tract and lungs of a wide variety of animals, including humans. The majority of human infections are due to either Cryptosporidium hominis (C. hominis...
A Functional Type I Interferon Pathway Drives Resistance to Cornea Herpes Simplex Virus Type 1 Infection by Recruitment of Leukocytes [0.03%]
通过募集白细胞驱动角膜HSV-1感染的I型干扰素通路的功能作用机制研究
Christopher D Conrady,Heather Jones,Min Zheng et al.
Christopher D Conrady et al.
Type I interferons are critical antiviral cytokines produced following herpes simplex virus type-1 (HSV-1) infection that act to inhibit viral spread. In the present study, we identify HSV-infected and adjacent uninfected corneal epithelial...