Instability of microsatellites linked to targeted genes in CRISPR/Cas9-edited and traditional gene knockout mouse strains [0.03%]
CRISPR/Cas9编辑和传统基因敲除小鼠品系中目标基因连锁的微卫星标记的不稳定性的研究
Xueyun Huo,Xiulin Zhang,Yihan Liu et al.
Xueyun Huo et al.
Control of flowering and inflorescence architecture in tomato by synergistic interactions between ALOG transcription factors [0.03%]
ALOG转录因子之间的协同作用调控番茄的开花和花序结构
Xiaozhen Huang,Lingli Tang,Yuan Yu et al.
Xiaozhen Huang et al.
Developing a one-step triplet-repeat primed PCR assay for diagnosing myotonic dystrophy [0.03%]
一步法.triplet-重复引物扩增聚合酶链反应诊断肌迟缓性营养不良症
Xiaoping Lan,Na Li,Hongling Wan et al.
Xiaoping Lan et al.
CGPS: A machine learning-based approach integrating multiple gene set analysis tools for better prioritization of biologically relevant pathways [0.03%]
基于机器学习的整合多种基因集分析工具的方法以更好地优先选择生物相关通路
Chen Ai,Lei Kong
Chen Ai
Gene set enrichment (GSE) analyses play an important role in the interpretation of large-scale transcriptome datasets. Multiple GSE tools can be integrated into a single method as obtaining optimal results is challenging due to the plethora...
Identifying normal embryos from reciprocal translocation carriers by whole chromosome haplotyping [0.03%]
通过全长染色体单倍体型识别易位携带者正常胚胎
Zhiqiang Yan,Yuqian Wang,Yanli Nie et al.
Zhiqiang Yan et al.
Characterization of a novel regulatory pathway for mannitol metabolism and its coordination with biofilm formation in Mycobacterium smegmatis [0.03%]
芽孢杆菌mannitol代谢的一种新型调节途径及其与生物被膜形成协调性的表征研究
Jialing Hu,Hua Zhang,Si Zhou et al.
Jialing Hu et al.
Biofilm formation has been implicated to be tightly regulated in bacteria. Mycobacterial species possess a unique cell-wall structure; however, the underlying regulation mechanism for their biofilm formation remains largely unclear. In this...
Tel1 and Rif2 oppositely regulate telomere protection at uncapped telomeres in Saccharomyces cerevisiae [0.03%]
Saccharomyces cerevisiae中Tel1和Rif2通过相反的途径调节未受保护端粒体的telomere防护功能
Ling-Li Zhang,Zhenfang Wu,Jin-Qiu Zhou
Ling-Li Zhang
It has been well documented that Tel1 positively regulates telomere-end resection by promoting Mre11-Rad50-Xrs2 (MRX) activity, while Rif2 negatively regulates telomere-end resection by inhibiting MRX activity. At uncapped telomeres, whethe...
Highly efficient genome editing using oocyte-specific zcas9 transgenic zebrafish [0.03%]
高效基因组编辑的卵细胞特异性ZcAsCas9转基因斑马鱼模型
Yuanyuan Liu,Chong Zhang,Yanjun Zhang et al.
Yuanyuan Liu et al.
Generation of two transgenic amphioxus lines using the Tol2 transposon system [0.03%]
使用Tol2转座系统建立两种刺尾鱼转基因系
Chenggang Shi,Jing Huang,Shixi Chen et al.
Chenggang Shi et al.
prpf4 is essential for cell survival and posterior lateral line primordium migration in zebrafish [0.03%]
prpf4是斑马鱼细胞存活和后侧线原基迁移的必需基因
Yixia Wang,Yanchao Han,Pengfei Xu et al.
Yixia Wang et al.
Prpf4 (pre-mRNA processing factor 4), a key component of spliceosome, plays critical roles in pre-mRNA splicing and its mutations result in retinitis pigmentosa due to photoreceptor defects. In this study, we characterized a zebrafish prpf4...