ZmFBL41 variants enhance maize resistance to Rhizoctonia solani by attenuating ZmFAH degradation and increasing fumaric acid accumulation [0.03%]
Jicheng Qu,Bao Lin,Tiantian Geng et al.
Jicheng Qu et al.
The F-box protein ZmFBL41, which targets ZmCAD and ZmNCED6, increases susceptibility to maize banded leaf and sheath blight (BLSB). Here, we report significantly reduced BLSB resistance in maize expressing the susceptible haplotype ZmFBL41B...
Dan Tian,Fengcui Qian,Lehan Pan et al.
Dan Tian et al.
TCRαβ+ double negative T (DNT) cells are increasingly being recognized for their critical roles in the progression of various diseases. However, the molecular and functional signatures remain poorly understood and controversial. In this s...
Natural variation of OsGATA16 contributes to differential immunity against Magnaporthe oryzae in rice [0.03%]
Hongjia Zhang,Zhao Li,Hong Li et al.
Hongjia Zhang et al.
Rice blast, caused by the fungal pathogen Magnaporthe oryzae, constitutes a critical threat to global rice production. Leveraging functional genes from germplasm resources to breed resistant varieties remains the most effective and sustaina...
Menghan Fan,Junfeng Dai,Zhigang Wu et al.
Menghan Fan et al.
Cereal crops often exhibit a tradeoff between thermotolerance, which is important for climate adaptation, and cell elongation, which is crucial for ideal plant architecture and yield. Here, we characterize the rice mutant with dwarfing and ...
Jingzhen Liu,Zhiwei Zhao,Hongtao Liu
Jingzhen Liu
Ultraviolet-B (UV-B) radiation (280-315 nm) is an essential component of sunlight that modulates various biological processes in plants. As the plant-specific UV-B photoreceptor, UV Resistance Locus 8 (UVR8) serves as the core molecule medi...
In vivo epigenome editing reduces circulating lipids and attenuates atherosclerosis in mice [0.03%]
体内表观基因组编辑可降低小鼠血循环中的脂质并减缓动脉粥样硬化发展
Wei Wang,Yingjie Zhang,Lin Chen et al.
Wei Wang et al.
Atherosclerotic cardiovascular disease remains the leading cause of global mortality, with hypercholesterolemia serving as a critical driver of atherogenesis. Although current lipid-lowering therapies substantially improve circulating lipid...
Xiaopeng Li,Yanhan Feng,Biyao Tang et al.
Xiaopeng Li et al.
Sex differences in health and disease are evident in humans and many other animal species. However, the sex-related determinants are less understood, and the underlying mechanisms remain elusive. By analyzing the RNA-Seq data, we unexpected...
A near-complete T2T genome assembly reveals a depleted immune repertoire as the genetic cause of endangerment in Carya poilanei [0.03%]
高质量基因组重测序揭示了Carya poilanei的濒危原因为免疫受体基因缺乏变异
Yuke Zhou,Jinchen Ye,Yingshan Chen et al.
Yuke Zhou et al.
Identification and functional characterization of STG5.2 conferring salt tolerance in rice [0.03%]
水稻耐盐基因STG5.2的鉴定及功能分析
Jie Ma,Yilin Li,Hongshuang Jiang et al.
Jie Ma et al.
Saline-alkaline stress severely constrains rice productivity, posing a critical threat to global food security. Identifying uncharacterized salt-tolerance genes with agronomic value is therefore essential for breeding stress-resilient and h...
Rational design for rice eating and cooking quality via combination of the Waxy and ALK haplotypes [0.03%]
利用Wx和ALK基因型组合的理性设计提高稻米食用和食味品质
Yuankang Cai,Qinglu Zhang,Yidan Ouyang et al.
Yuankang Cai et al.
Improving rice eating and cooking quality (ECQ) through designed breeding requires a precise understanding of functions and interactions of key gene haplotypes. Waxy and ALK are two major genes regulating ECQ, but how different combinations...