Lei Cai,Lan Alice Zheng,Lin He
Lei Cai
Medical genetics is the newest cutting-edge discipline that focuses on solving medical problems using genetics knowledge and methods. In China, medical genetics research activities initiated from a poor inner basis but a prosperous outer en...
Yidan Ouyang,Qifa Zhang
Yidan Ouyang
Reproductive isolation is defined as processes that prevent individuals of different populations from mating, survival or producing fertile offspring. Reproductive isolation is critical for driving speciation and maintaining species identit...
Huizhong Fan,Yibo Hu,Qi Wu et al.
Huizhong Fan et al.
Conservation genetics and genomics are two independent disciplines that focus on using new techniques in genetics and genomics to solve problems in conservation biology. During the past two decades, conservation genetics and genomics have e...
A legacy of the "1% program" - The "Chinese Chapter" of the human genome reference sequence [0.03%]
“1%计划”的中国贡献——人类基因组参考序列的“中国篇章”
Wei Dong,Xiaoling Wang,Zhi Xia et al.
Wei Dong et al.
Fruit fly research in China [0.03%]
中国的果蝇研究
Ying Cheng,Dahua Chen
Ying Cheng
Served as a model organism over a century, fruit fly has significantly pushed forward the development of global scientific research, including in China. The high similarity in genomic features between fruit fly and human enables this tiny i...
Cheng-Guo Duan,Jian-Kang Zhu,Xiaofeng Cao
Cheng-Guo Duan
Epigenetics refers to the study of heritable changes in gene function that do not involve changes in the DNA sequence. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors or be part...
Shiwei Bai,Hong Yu,Bing Wang et al.
Shiwei Bai et al.
Breeding is the art and science of selecting and changing crop traits for the benefit of human beings. For several decades, tremendous efforts have been made by Chinese scientists in rice breeding in improving grain yield, nutrition quality...
Genomic landscapes of Chinese sporadic autism spectrum disorders revealed by whole-genome sequencing [0.03%]
全基因组测序揭示中国散发性自闭症谱系障碍的基因组特征
Jinyu Wu,Ping Yu,Xin Jin et al.
Jinyu Wu et al.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder with considerable clinical and genetic heterogeneity. In this study, we identified all classes of genomic variants from whole-genome sequencing (WGS) dataset of 32 Chinese trio...
Gene diagnosis and targeted breeding for blast-resistant Kongyu 131 without changing regional adaptability [0.03%]
广适型抗稻瘟病新品种空育131基因诊断及定向育种
Xiangchun Zhou,Gonghao Jiang,Longwei Yang et al.
Xiangchun Zhou et al.
The fungus Magnaporthe oryzae threatens the rice production of Kongyu 131 (KY131), a leading japonica variety in Northeast China. In this study, two rice lines, KP1 and KP2-Hd1, were obtained by introgressing the blast resistance genes Pi1 ...
The present and future of whole-exome sequencing in studying and treating human reproductive disorders [0.03%]
全外显子组测序在人类生殖障碍研究与治疗的现状及未来展望
Wei Guo,Xiaohui Zhu,Liying Yan et al.
Wei Guo et al.
The causes of recurrent spontaneous abortion (RSA) and fetal malformations are multifactorial and unclear in most cases. Environmental, maternal, and genetic factors have been shown to contribute to these defects. Whole-exome sequencing (WE...