Identification and characterization of rice blast resistance gene Pid4 by a combination of transcriptomic profiling and genome analysis [0.03%]
结合转录组和基因组分析鉴定水稻抗稻瘟病基因Pid4
Zhixiong Chen,Wen Zhao,Xiaobo Zhu et al.
Zhixiong Chen et al.
Map-based cloning of plant disease resistance (R) genes is time-consuming. Here, we reported the isolation of blast R gene Pid4 using comparative transcriptomic profiling and genome-wide sequence analysis. Pid4 encodes a coiled-coil nucleot...
ZFN, TALEN and CRISPR-Cas9 mediated homology directed gene insertion in Arabidopsis: A disconnect between somatic and germinal cells [0.03%]
拟南芥中通过锌指核酸酶、转录激活因子样效应物核酸酶和CRISPR-Cas9介导的同源依赖基因插入：无性细胞和生殖细胞之间的差异
Qiwei Shan,Nicholas J Baltes,Paul Atkins et al.
Qiwei Shan et al.
Loss of miR-83 extends lifespan and affects target gene expression in an age-dependent manner in Caenorhabditis elegans [0.03%]
线虫miR-83的丧失延长了寿命并以年龄依赖性的方式影响靶基因表达
Emmanuel Enoch Dzakah,Ahmed Waqas,Shuai Wei et al.
Emmanuel Enoch Dzakah et al.
MicroRNAs (miRNAs) are short non-coding RNAs that are involved in the post-transcriptional regulation of protein-coding genes. miRNAs modulate lifespan and the aging process in a variety of organisms. In this study, we identified a role of ...
Generating a reporter mouse line marking medium spiny neurons in the developing striatum driven by Arpp21 cis-regulatory elements [0.03%]
利用Arpp21顺式调控元件在发育纹状体中生成标记中棘神经元的报告小鼠品系
Pan Chen,Xiangbin Ruan,Yongqiang Chen et al.
Pan Chen et al.
Drosophila homolog of the intellectual disability-related long-chain acyl-CoA synthetase 4 is required for neuroblast proliferation [0.03%]
长链酰基辅酶a合成酶4同源物是神经干细胞增殖所必需的——对智力障碍具有重要意义
Mingyue Jia,Danqing Meng,Mo Chen et al.
Mingyue Jia et al.
Mutations in long-chain acyl-CoA synthetase 4 (ACSL4) are associated with non-syndromic X-linked intellectual disability (ID). However, the neural functions of ACSL4 and how loss of ACSL4 leads to ID remain largely unexplored. We report her...
Jinquan Liu,Meiling Zhao,Bo Yuan et al.
Jinquan Liu et al.
Smads are critical intracellular signal transducers for transforming growth factor-β (TGF-β) in mammalian cells. In this study, we have identified WD repeat-containing protein 74 (WDR74) as a novel transcriptional coactivator for Smads in...
Individual blastomeres of 4- and 8-cell embryos have ability to develop into a full organism in mouse [0.03%]
小鼠4细胞和8细胞胚胎的每一个卵裂球均具有发育成为完整生物个体的能力
Xinxin Zhang,Tianda Li,Linlin Zhang et al.
Xinxin Zhang et al.
CRISPR/Cas9-introduced single and multiple mutagenesis in strawberry [0.03%]
草莓中的CRISPR/Cas9单突变和多突变技术
Sinian Xing,Meiru Jia,Lingzhi Wei et al.
Sinian Xing et al.
James A Birchler
James A Birchler
Yongbiao Xue,Yaping Zhang
Yongbiao Xue