IGF-1-mediated upregulation of gut Blautia correlates with inflammatory markers in hormone-secreting pituitary adenomas [0.03%]
生长激素腺瘤患者血清IGF-1上调肠道菌群Blautia与炎症标志物的相关性研究
Zekun Deng,Siyu Chen,Yong She et al.
Zekun Deng et al.
Near-gapless telomere-to-telomere reference nuclear genome and variable mitochondrial genome of Amborella trichopoda [0.03%]
近乎无间隙端粒到端粒的核基因组参考序列和 trigonous 树枝花的变异型线粒体基因组
Zhonglong Guo,Jing-Fang Guo,Zhi-Yan Wei et al.
Zhonglong Guo et al.
The circadian clock at the intersection of metabolism and aging - emerging roles of metabolites [0.03%]
代谢与衰老交汇处的生物钟——代谢物的新角色
Yue Dong,Sin Man Lam,Yan Li et al.
Yue Dong et al.
The circadian clock is a highly hierarchical network of endogenous pacemakers that primarily maintains and directs oscillations through transcriptional and translational feedback loops, which modulates an approximately 24-hour cycle of endo...
Wanqing Bai,Ziyi Yang,Xuchang Yu et al.
Wanqing Bai et al.
Neutrophils disrupt the intestinal barrier via IL-22/TGF-β/Mmp9 axis in the zebrafish model of inflammatory bowel disease [0.03%]
中性粒细胞通过IL-22/TGF-β/Mmp9轴在斑马鱼炎症性肠病模型中破坏肠道屏障功能
Peixian Huang,Yiqing Yang,Junwei Lian et al.
Peixian Huang et al.
Lanjun Zhang,Chengxu Gao,Yihong Gao et al.
Lanjun Zhang et al.
The plant cell wall is an extremely complicated natural nanoscale structure composed of cellulose microfibrils embedded in a matrix of noncellulosic polysaccharides, further reinforced by the phenolic compound lignins in some cell types. Su...
RiboParser/RiboShiny: an integrated platform for comprehensive analysis and visualization of Ribo-seq data [0.03%]
RiboParser/RiboShiny：一个集中的里博序列数据分析和可视化平台
Shuchao Ren,Yinan Li,Zhipeng Zhou
Shuchao Ren
Translation is a crucial step in gene expression. Over the past decade, the development and application of Ribosome profiling (Ribo-seq) have significantly advanced our understanding of translational regulation in vivo. However, the analysi...
Regulation of maize kernel development via divergent activation of α-Zein genes by transcription factors O11, O2, and PBF1 [0.03%]
转录因子O11、O2和PBF1通过拮抗调节α-醇溶蛋白基因的表达从而调控玉米籽粒发育
Runmiao Tian,Zeyuan Yang,Ruihua Yang et al.
Runmiao Tian et al.
α-Zeins, the major maize endosperm storage proteins, are transcriptionally regulated by Opaque 2 (O2) and PROLAMIN-BOX BINDING FACTOR1 (PBF1), with Opaque 11 (O11) functioning upstream of them. However, whether O11 directly binds to α-zei...
Rhpn2 regulates the development and function of vestibular sensory hair cells through the RhoA signaling in zebrafish [0.03%]
Rhpn2通过RhoA信号通路调控斑马鱼前庭感觉毛细胞的发育和功能
Yubei Dai,Qianqian Li,Jiaju Deng et al.
Yubei Dai et al.
Hearing and balance disorders are significant health issues primarily caused by developmental defects or the irreversible loss of sensory hair cells (HCs). Identifying the underlying genes involved in the morphogenesis and development of HC...
GCH1 contributes to high-altitude adaptation in Tibetans by regulating blood nitric oxide [0.03%]
GCH1通过调节血液一氧化氮促进藏族人民的高原适应性
Yongbo Guo,Wangshan Zheng,Tian Yue et al.
Yongbo Guo et al.
Nitric oxide (NO) is a key vasodilator that regulates vascular pressure and blood flow. Tibetans have developed a "blunted" mechanism for regulating NO levels at high altitude, with GTP cyclohydrolase 1 (GCH1) identified as a key candidate ...