Assembly of a high-quality reference genome and characterization of a chemical-mutagenized library of an elite soybean cultivar Tianlong 1 [0.03%]
优质大豆品种铁丰1号基因组测序及其化学诱变突变体库的特征分析
Yinghua Sheng,Yicheng Huang,Zilun Jin et al.
Yinghua Sheng et al.
Soybean (Glycine max L.) is a globally vital crop for oil production and food security. High-quality genomic resources are instrumental for both functional genomics and breeding. Here, we report a near-complete, high-quality genome assembly...
Recapitulation of key phenotypes and pathological features of primary familial brain calcification (PFBC) in a mouse Slc20a2S602W/S602W model [0.03%]
Slc20a2S602W/S602W小鼠模型原发性家族性脑钙化(PFBC)主要表型和病理特征的总结
Junyu Luo,Man Jiang,Jun Liu et al.
Junyu Luo et al.
Gene traffic mediated by transposable elements shaped the dynamic evolution of ancient sex chromosomes of varanid lizard [0.03%]
转座元件介导的基因流动塑造了巨蜥科古老性染色体的动态演化
Zexian Zhu,Jason Dobry,Erik Wapstra et al.
Zexian Zhu et al.
Lizards usually exhibit frequent turnovers and a much greater diversity of sex determination mechanisms compared to birds and mammals, with the conserved ZW sex chromosomes of anguimorph lizards originating over 115 million years ago a seem...
Spatiotemporal dynamics of neuron differentiation and migration in the developing human spinal cord [0.03%]
发育中的人类脊髓神经元分化和迁移的时空动态学
Yuan Yu,Mengjie Pan,Quanyou Cai et al.
Yuan Yu et al.
Precise formation of complex neural circuits in the spinal cord, achieved through the integration of diverse neuronal populations, is essential for central nervous system function. However, the specialization and migration of human spinal c...
tsRNADisease: a manually curated database of tsRNAs associated with human disease [0.03%]
tsRNADisease:与人类疾病相关的tsRNA手动注释数据库
Hui Yang,Shaoying Zhu,Huijun Wei et al.
Hui Yang et al.
tRNA-derived small RNAs (tsRNAs), as a class of regulatory small noncoding RNA, have been implicated in a wide variety of human diseases. Large amounts of tsRNA-disease associations have been identified in recent years from accumulating stu...
A telomere-to-telomere genome assembly of radish (Raphanus sativus L.) provides insights into QTL mapping of bolting traits [0.03%]
蔊菜(春芥)端粒到端粒基因组组装为抽薹性状QTL定位提供见解
Feng Yang,Sihan Peng,Shuai Yuan et al.
Feng Yang et al.
Radish (Raphanus sativus L.) is an important cruciferous root vegetable, with bolting regulated by multiple genes; however, the genetic mechanisms underlying bolting regulation remain unclear. Here, the genome of the cultivar C60213 is asse...
Chromosome-level genome assembly of finger millet (Eleusine coracana) provides insights into drought resistance [0.03%]
高粱族小米基因组高质量全基因组序列及抗旱研究
Jiguang Li,Chaonan Guan,Xiaobo Li et al.
Jiguang Li et al.
Finger millet (Eleusine coracana Gaertn.), a nutritionally rich and drought-resilient C4 cereal, possesses exceptional grain storage longevity (up to 50 years). Here, we report a high-quality genome assembly of the allotetraploid cultivar C...
Proximity labeling proteomics with cilia-TurboID transgenic mice identified regulators of motile cilia function [0.03%]
利用cilia-TurboID转基因小鼠进行邻近标记蛋白质组学鉴定可调节运动纤毛功能的调控因子
Pan Wang,Xiangnan Wu,Liqing Xiao et al.
Pan Wang et al.
Jian Wang,Dagang Chen,Haifei Hu et al.
Jian Wang et al.
Leaf thickness in rice critically influences photosynthetic efficiency and yield, yet its genetic basis remains poorly understood, with few functional genes previously characterized. In this study, we employ a pangenome-wide association stu...