Maize Chlorotic Leaf Spot1 encodes a fumarylacetoacetate hydrolase essential for carbohydrate partitioning [0.03%]
玉米叶斑病基因Chlorotic Leaf Spot 1编码扁桃酸乙酰化酶并将其鉴定为糖类代谢的必需因子
Ruchang Ren,Sihang Zhao,Hong Jia et al.
Ruchang Ren et al.
Carbohydrate partitioning from photosynthetic sources to non-photosynthetic sinks is essential for plant development and crop yield. Using a maize-teosinte BC2S3 population, we identify Chlorotic Leaf Spot1 (CLS1), a fumarylacetoacetate hyd...
Genomic insights into population structure, adaptation, and archaic introgression at the Himalayan-East Asian crossroads [0.03%]
青藏高原与东亚交汇处的群体结构、适应及 Denisovan 混合的基因组学见解
Mengge Wang,Shuhan Duan,Qiuxia Sun et al.
Mengge Wang et al.
Tibetan-Yi Corridor (TYC) is a crucial agro-pastoral region in the eastern Himalayas, linking Qinghai‒Xizang Plateau with the lowlands of East Asia and facilitating human migration for millennia. However, genomic research on TYC population...
Single-molecule chromatin profiling reveals cell type-specific A/B compartment alteration and multi-enhancer transcriptional coordination [0.03%]
单分子染色质分析揭示了细胞类型特异性A/B区室变化和多增强子转录协调
Luo-Ran Liu,Jia-Yong Zhong,Xin Bai et al.
Luo-Ran Liu et al.
In eukaryotic organisms, the three-dimensional organization and epigenomic landscape of chromatin are fundamental to the regulation of gene expression. Previous studies have provided significant insights into CpG methylation, chromatin acce...
circRNAs derived from a nuclear hormone receptor act differentially on insect metamorphosis and reproduction [0.03%]
一种核激素受体来源的环状RNA对昆虫变态和生殖产生不同的作用
Lulu Gao,Qiang Yan,Ying Qu et al.
Lulu Gao et al.
Insects are the most diverse group on earth, partially owing to their metamorphosis and strong fecundity. Circular RNAs (circRNAs) are stable molecules implicated in a broad range of biological processes. However, the regulatory roles of ci...
Dissecting the genetic basis of reproductive transition and reproductive growth in wheat by considering accumulated temperature [0.03%]
通过考虑累积温度分析小麦生殖过渡和生殖生长的遗传基础
Liujie Jin,Kening Duo,Chao Fu et al.
Liujie Jin et al.
Genetic innovations underlying the evolution of root nodule symbiosis in Leguminosae [0.03%]
豆科植物根瘤共生固氮进化过程中的基因创新
Tengfei Liu,Hao Lin,Zhixi Tian
Tengfei Liu
Root nodule symbiosis (RNS) is a mutualistic association formed between nitrogen-fixing rhizobia or Frankia and host plants limited to four orders within Rosid I-Fabales, Fagales, Cucurbitales and Rosales-which comprise the so-called 'Nitro...
A SABRE family protein DITA1 regulates plant height and tiller angle in rice [0.03%]
水稻中的SABRE家族蛋白DITA1调控植株高度及分蘖角度
Ting Zou,Jing Liang,Shiyue Xing et al.
Ting Zou et al.
Rice plant architecture is shaped by complex agronomic traits, such as plant height and tiller angle, which collectively determine yield potential. Although SABRE family proteins are conserved across eukaryotes, their roles in regulating pl...
Application of an optimized non-invasive prenatal testing for thalassemia based on change of haplotype doses [0.03%]
基于单体型剂量变化的优化无创产前筛查地中海贫血的应用研究
Fei Sun,Yao Zhou,Xing Zhao et al.
Fei Sun et al.
Patients affected by monogenic diseases impose a substantial burden on both themselves and their families. The primary preventive measure, i.e., invasive prenatal diagnosis, carries a risk of miscarriage and cannot be performed early in pre...
A telomere-to-telomere genome assembly of the large yellow croaker provides insights into evolution of golden-yellow coloration [0.03%]
金乌贼染色体水平基因组的telomere-to-telomere组装为金色黄化表型进化提供新见解
Shengyong Xu,Qi Liu,Tianyan Yang et al.
Shengyong Xu et al.
The large yellow croaker (Larimichthys crocea) is a flagship marine fish in China given its extreme commercial value and golden-yellow coloration. However, the genetic mechanisms underlying golden-yellow coloration remain unclear. Here, we ...
Deep insights and clinical benefits from the comprehensive cohort of fetal skeletal dysplasia in China [0.03%]
中国胎儿骨骼发育不良全面队列的深度洞察和临床优势
Guozhuang Li,Kexin Xu,Jihao Cai et al.
Guozhuang Li et al.
Fetal skeletal dysplasia (FSD) encompasses diverse clinical features and complicates prenatal diagnosis and perinatal care. In this retrospective study, we integrate prenatal deep phenotyping with exome or genome sequencing (ES/GS) to eluci...