Uncovering the chromatin-mediated transcriptional regulatory network governing cold stress responses in fish immune cells [0.03%]
鱼类免疫细胞抵御冷应力的染色质介导的转录调控网络解析
He Jiao,Songqian Huang,Minghao Zhang et al.
He Jiao et al.
Temperature fluctuations challenge ectothermic species, particularly tropical fish dependent on external temperatures for physiological regulation. However, the molecular mechanisms through which low-temperature stress impacts immune respon...
S-Sulfenylation-mediated inhibition of the GSNOR1 activity regulates ovule development in Arabidopsis [0.03%]
硫亚硫酸盐介导的GSNOR1抑制调控拟南芥胚珠发育
Shina Sun,Peng-Fei Jia,Wan Wang et al.
Shina Sun et al.
Reactive oxygen species (ROS) and nitric oxide (NO) are two critical classes of signaling molecules that regulate plant development and stress responses. The intracellular level of S-nitrosoglutathione (GSNO), a major bioactive NO species, ...
A critical evaluation of deep-learning based phylogenetic inference programs using simulated data sets [0.03%]
基于模拟数据集对深度学习系谱推断程序的批判性评估
Yixiao Zhu,Yonglin Li,Chuhao Li et al.
Yixiao Zhu et al.
Biallelic variants in SREBF2 cause autosomal recessive spastic paraplegia [0.03%]
SREBF2双等位基因变异导致常染色体隐性遗传的共济失调-脊髓病
Qiao Wei,Wenlu Fan,Hong-Fu Li et al.
Qiao Wei et al.
Hereditary spastic paraplegias (HSPs) refer to a genetically and clinically heterogeneous group of neurodegenerative disorders characterized by the degeneration of motor neurons. To date, a significant number of patients still have not rece...
Identification of QTL-by-environment interaction by controlling polygenic background effect [0.03%]
通过控制多基因背景效应鉴定基因型-环境互作的QTL
Fuping Zhao,Lixian Wang,Shizhong Xu
Fuping Zhao
The QTL by environment interaction (Q×E) effect is hard to detect because there are no effective ways to control the genomic background. In this study, we propose a novel linear mixed model that simultaneously analyzes data from multiple e...
Enhancing crop yields to ensure food security by optimizing photosynthesis [0.03%]
通过优化光合作用提高作物产量以确保粮食安全
Chunrong Li,Xuejia Du,Cuimin Liu
Chunrong Li
The crop yields achieved through traditional plant breeding techniques appear to be nearing a plateau. Therefore, it is essential to accelerate advancements in photosynthesis, the fundamental process by which plants convert light energy int...
The maize mTERF18 regulates transcriptional termination of the mitochondrial nad6 gene and is essential for kernel development [0.03%]
玉米mTERF18通过调控线粒体nad6基因的转录终止促进雌配子发育以确保籽实形成
Zhengwei Guan,Yong Wang,Jun Yang
Zhengwei Guan
Mitochondria are semi-autonomous organelle present in eukaryotic cells, containing their own genome and transcriptional machinery. However, their functions are intricately linked to proteins encoded by the nuclear genome. Mitochondrial tran...
Genomic characterization reveals distinct mutational landscape of acral melanoma in East Asian [0.03%]
基因组分析揭示了东亚肢端黑色素瘤的独特突变特征
Fenghao Zhang,Xiaowen Wu,Tao Jiao et al.
Fenghao Zhang et al.
Acral melanoma, the most common melanoma subtype in East Asia, is associated with a poor prognosis. This study aims to comprehensively analyze the genomic characteristics of acral melanoma in East Asians. We conduct whole-genome sequencing ...
Genetic interaction network of quantitative trait genes for heading date in rice [0.03%]
水稻开花期数量性状基因的遗传互作网络研究
Mengjiao Chen,Yifeng Hong,Jiongjiong Fan et al.
Mengjiao Chen et al.
Several quantitative trait genes (QTGs) related to rice heading date, a key factor for crop development and yield, have been identified, along with complex interactions among genes. However, a comprehensive genetic interaction network for t...
Vitamin D receptor regulates methyltransferase like 14 to mitigate colitis-associated colorectal cancer [0.03%]
维生素D受体通过调节甲基转移酶样蛋白14防治结肠炎相关的结直肠癌
Zheng Wang,Lingjuan Jiang,Xiaoyin Bai et al.
Zheng Wang et al.
Colitis-associated colorectal cancer (CAC), a serious complication of ulcerative colitis (UC), is associated with a poor prognosis. The vitamin D receptor (VDR) is recognized for its protective role in UC and CAC through the maintenance of ...