Diverse functions of sex determination gene doublesex on sexually dimorphic neuronal development and behaviors [0.03%]
性别决定基因doublesex在性二态神经元发育及行为中的多种功能
Jiangtao Chen,Wen Tu,Ziqi Li et al.
Jiangtao Chen et al.
Sex-specific neurons play pivotal roles in regulating sexually dimorphic behaviors. In insects, the sex determination gene doublesex (dsx) establishes major sexual dimorphism of the nervous system, in which male-specific dsxM promotes neuro...
Mengshan Ni,Yinmeng Zhu,Yufei Chen et al.
Mengshan Ni et al.
mTORC1/2 play central roles as signaling hubs of cell growth and metabolism and are therapeutic targets for several diseases. However, the human genetic evidence linking mutations of mTORC1/2 to obesity remains elusive. Using whole-exome se...
Varying Bifidobacterium species in the maternal-infant gut microbiota correlate with distinct early neurodevelopmental outcomes [0.03%]
母胎肠道微生物群中不同的双歧杆菌与不同的早期神经发育结果相关
Cong Liu,Qun Lu,Qi Xi et al.
Cong Liu et al.
The impact of mother-infant microbiota on neurodevelopment is an area of interest, but longitudinal studies are scarce. Using a cohort of 520 families from the Jiangsu birth cohort in China, we reveal that the maternal gut microbiota during...
Decoding maize meristems maintenance and differentiation: integrating single-cell and spatial omics [0.03%]
单细胞和空间组学在解码玉米分生组织维持与分化中的应用整合
Bin Li,Wenhao Liu,Jie Xu et al.
Bin Li et al.
All plant organs are derived from stem cell-containing meristems. In maize, the shoot apical meristem (SAM) is responsible for generating all above-ground structures, including the male and female inflorescence meristems (IMs), which give r...
uniLIVER: a human liver cell atlas for data-driven cellular state mapping [0.03%]
uniLIVER：人类肝脏细胞图谱，用于数据驱动的细胞状态映射
Yanhong Wu,Yuhan Fan,Yuxin Miao et al.
Yanhong Wu et al.
The liver performs several vital functions such as metabolism, toxin removal, and glucose storage through the coordination of various cell types. With the recent breakthrough of the single-cell/single-nucleus RNA-seq (sc/snRNA-seq) techniqu...
Genomic predictions of invasiveness and adaptability of the cotton bollworm in response to climate change [0.03%]
气候变化下棉铃虫入侵性和适应性的基因组预测
Qi Xu,Minghui Jin,Hua Xiao et al.
Qi Xu et al.
Agricultural pests cause enormous losses in annual agricultural production. Understanding the evolutionary responses and adaptive capacity of agricultural pests under climate change is crucial for establishing sustainable and environmentall...
LG1 promotes preligule band formation through directly activating ZmPIN1 genes in maize [0.03%]
LG1通过直接激活玉米ZmPIN1基因促进叶鞘边缘带的形成
Zhuojun Zhong,Minhao Yao,Yingying Cao et al.
Zhuojun Zhong et al.
Increasing plant density is an effective strategy for enhancing crop yield per unit land area. A key architectural trait for crops adapting to high planting density is smaller leaf angle (LA). Previous studies have demonstrated that LG1, a ...
Maize transcription factor ZmEREB167 negatively regulates starch accumulation and kernel size [0.03%]
玉米转录因子ZmEREB167通过负调控淀粉积累和胚乳细胞分裂抑制籽粒大小
Xiangyu Qing,Jianrui Li,Zhen Lin et al.
Xiangyu Qing et al.
Transcription factors play critical roles in the regulation of gene expression during maize kernel development. The maize endosperm is a large storage organ, accounting for nearly 90% of the dry weight of mature kernel, and is also the main...
Multifaceted interplays between the essential players and lipid peroxidation in ferroptosis [0.03%]
铁死亡中关键调控因子与脂质氧化的相互作用
Conghe Liu,Zhihao Liu,Zheng Dong et al.
Conghe Liu et al.
Ferroptosis, a type of programmed cell death, represents a distinct paradigm in cell biology. It is characterized by the iron-dependent accumulation of reactive oxygen species, which induce lipid peroxidation (LPO), and is orchestrated by t...
The HISTONE ACETYLTRANSFERASE 1 interacts with CONSTANS to promote flowering in Arabidopsis [0.03%]
组蛋白乙酰转移酶1通过与开花抑制子CONSTANS互作促进拟南芥开花响应
Zhenwei Liang,Yisui Huang,Yuanhao Hao et al.
Zhenwei Liang et al.
Chromatin modifications including histone acetylation play essential roles in regulating flowering. The CBP/p300 family HISTONE ACETYLTRANSFERASE 1 (HAC1), which mediates histone acetylation, promotes the process of floral transition; howev...