High-throughput technologies for gene expression analyses: what we have learned for noise-induced cochlear degeneration? [0.03%]
高通量技术在基因表达分析中的应用——耳鸣导致的感音神经性聋患者的分子特征研究
Bo Hua Hu
Bo Hua Hu
Noise-induced hearing loss is a common cause of acquired hearing loss in the adult population. Acoustic overstimulation causes cochlear damage through mechanical stress to the tissue. Consequently, complex molecular changes are initiated, a...
OTOTOXIC EFFECTS OF CARBOPLATIN IN ORGANOTYPIC CULTURES IN CHINCHILLAS AND RATS [0.03%]
卡普莫司汀耳毒性器官培养模型的建立及应用研究
Ding Dalian,Jiang Haiyan,Fu Yong et al.
Ding Dalian et al.
Carboplatin, a second-generation platinum chemotherapeutic drug, is considerably less ototoxic than cisplatin. While common laboratory species such as mice, guinea pigs and rats are highly resistant to carboplatin ototoxicity, the chinchill...
Ototoxic Model of Oxaliplatin and Protection from Nicotinamide Adenine Dinucleotide [0.03%]
奥沙利铂耳毒性模型及其尼古틴酰胺腺嘌呤二核苷酸的保护作用
Ding Dalian,Jiang Haiyan,Fu Yong et al.
Ding Dalian et al.
Oxaliplatin, an anticancer drug commonly used to treat colorectal cancer and other tumors, has a number of serious side effects, most notably neuropathy and ototoxicity. To gain insights into its ototoxic profile, oxaliplatin was applied to...
MEASUREMENT OF AMPLITUDE AND DELAY OF STIMULUS FREQUENCY OTOACOUSTIC EMISSIONS [0.03%]
声频诱发otoacoustic发射的幅度和延迟测量
Tianying Ren,Jiefu Zheng,Wenxuan He et al.
Tianying Ren et al.
Although stimulus frequency otoacoustic emissions (SFOAEs) have been used as a non-invasive measure of cochlear mechanics, clinical and experimental application of SFOAEs has been limited by difficulties in accurately deriving quantitative ...
Electrically evoked auditory nerve responses in the cochlea with normal outer hair cells [0.03%]
外毛细胞正常情况下耳蜗中电诱发听神经反应
Tianying Ren,Menghe Guo,Wenxuan He et al.
Tianying Ren et al.
As hybrid cochlear implant devices are increasingly used for restoring hearing in patients with residual hearing it is important to understand electrically evoked responses in cochleae having functional hair cells. To test the hypothesis th...