Clinical features, treatment strategies and outcomes of hepatocellular carcinoma in association with type 1 Abernethy malformation: an evaluation of a pooled case series [0.03%]
I型艾宾奴帝畸形合并肝细胞癌的临床特征、治疗策略及预后分析：病例系列研究
Fred Ahmadi,Vatsal Khanna,Leonid Shamban
Fred Ahmadi
Introduction and objectives: Abernethy malformation, also known as congenital extrahepatic portosystemic shunt (CEPS), is a rare vascular anomaly characterized by diversion of portal venous blood into the systemic circula...
A multisociety consensus statement on a new common definition and diagnostic criteria for PSVD or NCPF [0.03%]
慢加急性肝衰竭/急性格林巴利综合征诊断国际共识陈述
Virginia Hernandez-Gea,Valerie Paradis,Maha Guindi et al.
Virginia Hernandez-Gea et al.
Noncirrhotic portal hypertension has historically been described using heterogeneous and region-specific terminology-such as idiopathic portal hypertension (IPH), noncirrhotic portal fibrosis (NCPF), obliterative portal venopathy, and nodul...
Practice Guideline
Annals of hepatology. 2026 May 27:102219. DOI:10.1016/j.aohep.2026.102219 2026
Beyond hazard ratios: interpreting trial endpoints and survival analysis in systemic therapy for hepatocellular carcinoma [0.03%]
超越危险比率：肝细胞癌系统治疗试验终点和生存分析的解读
Federico Piñero,Stephen L Chan,Arndt Vogel
Federico Piñero
Hepatocellular carcinoma (HCC) therapy has evolved rapidly with the introduction of immune checkpoint inhibitors and targeted anti‑angiogenic agents. Randomized clinical trials remain the cornerstone for evaluating treatment efficacy, yet ...
A prospective cohort validation study of a multivariable algorithm ASAP for risk stratification of surveillance for hepatocellular carcinoma [0.03%]
一项用于肝细胞癌监测风险分层的多变量算法ASAP的前瞻性队列验证研究
Wei-Lun Liou,Si-Yu Tan,Laurel Jackson et al.
Wei-Lun Liou et al.
Introduction and objectives: ASAP is a multivariable risk model for hepatocellular carcinoma (HCC). This prospective pilot study evaluated its performance, based on a previously established cut-off value, in predicting HC...
Hepatocellular Carcinoma in Honduras (2014-2023): Nationwide Trends in Hospital Discharges and Mortality [0.03%]
洪都拉斯的肝细胞癌（2014-2023）：住院和死亡率的全国趋势
Larissa Acosta Salgado,Daniela Sofia Cruz Betanco,Gisela Pattarone et al.
Larissa Acosta Salgado et al.
Introduction and objectives: Hepatocellular carcinoma (HCC) is a growing global health concern, yet data from Central America remain scarce. This study presents the first nationwide analysis of hospital discharges and mor...
Simple model stratifies liver cancer risk in non-cirrhotic chronic hepatitis C patients after viral eradication [0.03%]
简单的模型可对慢性丙型肝炎非 cirrhosis 患者病毒清除后肝癌风险进行分层
Yen-Chun Liu,Te-Sheng Chang,Chi-Yi Chen et al.
Yen-Chun Liu et al.
Introduction and objectives: Current guidelines recommend hepatocellular carcinoma (HCC) surveillance only in cirrhotic chronic hepatitis C (CHC) patients after sustained virologic response (SVR). With the cost-effectiven...
Association between antihypertensive medications and hepatocellular carcinoma risk in individuals with metabolic dysfunction-associated steatotic liver disease (MASLD) without cirrhosis [0.03%]
代谢功能紊乱相关肝脂肪变性疾病(MASLD)患者无肝硬化组降压药与肝细胞癌风险的关联研究
Hao-Chien Hung,Po-Jung Hsu,Yin Lai et al.
Hao-Chien Hung et al.
Introduction and objectives: Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major risk factor for HCC. Antihypertensive medica...
Five years after IMbrave150 with clinical integration of atezolizumab plus bevacizumab in hepatocellular carcinoma [0.03%]
阿特珠单抗联合贝伐珠单抗治疗肝细胞癌的临床整合——IMbrave150研究五年后
Kuan-Chang Lai,San-Chi Chen
Kuan-Chang Lai
Five years after IMbrave150, atezolizumab plus bevacizumab (ate/bev) remains the first-line standard for unresectable hepatocellular carcinoma (uHCC). High response rates allow downstaging and curative conversion, enabling drug-free remissi...
The absence of the alpha-7 nicotinic acetylcholine receptor impairs liver regeneration due to altered autophagic response after resection [0.03%]
α7烟碱型乙酰胆碱受体的缺失通过改变肝脏切除后的自噬反应而损害肝再生
Franciely Alves da Silva,Ana Laura Vieira da Silva,Marcos Vinícius Esteca et al.
Franciely Alves da Silva et al.
Introduction and objectives: The α7 nicotinic acetylcholine receptor (α7nAChR) plays a central role in modulating inflammation and cellular homeostasis. However, its role in liver regeneration remains poorly understood....
Trends of metabolic dysfunction-associated steatotic liver disease in Mexico, 1990-2023: insights from the Global Burden of Disease Study [0.03%]
1990-2023年墨西哥代谢功能障碍相关脂肪性肝病流行趋势：来自全球疾病负担研究的启示
Israel Rico-Alba,Alberto Retana-Guzmán,Marcela Agudelo-Botero et al.
Israel Rico-Alba et al.
Introduction and objectives: Metabolic dysfunction-associated steatotic liver disease (MASLD) has emerged as a rapidly increasing global public health challenge. The objective was to analyze MASLD trends in Mexico by sex ...