Development and validation of mPCR-CEFA for detecting multiple deletion and non-deletion thalassemia genotypes [0.03%]
用于检测多种缺失和非缺失型地中海贫血基因型的mPCR-CEFA的建立与验证
Jingping Xu,Baoyan Ren,Qixun Fang et al.
Jingping Xu et al.
Background: Thalassemia is a common hereditary blood disorder caused by genetic variants in globin genes, leading to abnormal hemoglobin production. Rapid and accurate genotyping is essential for molecular screening and p...
Retraction: EZH2-mediated microRNA-375 upregulation promotes progression of breast cancer via the inhibition of FOXO1 and the p53 signaling pathway [0.03%]
撤稿：EZH2介导的microRNA-375上调通过抑制FOXO1和p53信号通路促进乳腺癌进展
Frontiers Editorial Office
Frontiers Editorial Office
[This retracts the article DOI: 10.3389/fgene.2021.633756.]. Copyright © 2025 Frontiers Editorial Office.
Identification of variants in SWI/SNF complex genes associated with neurodevelopmental disorders [0.03%]
与神经发育障碍相关的SWI/SNF复合体基因变异的鉴定
Chen Liang,Haihong Shi,Yanjuan Chen et al.
Chen Liang et al.
Introduction: Neurodevelopmental disorder (NDDs) such as intellectual disability, developmental delay encompasses a diverse group of conditions caused by the disruptions in the central nervous system (CNS) during developm...
Comprehensive bioinformatics analysis of malignant transformation and potential therapeutic possibility of lung adenocarcinoma after lipopolysaccharide induction [0.03%]
脂多糖诱导肺癌腺癌恶性转化的生物信息学分析及潜在治疗可能性研究
Wanjie Xu,Jing Zhang,Xinyu Zhang et al.
Wanjie Xu et al.
Background: Lipopolysaccharides are involved in malignant progression and epithelial-mesenchymal transition of cancer. The mechanism of LPS in malignant progression of lung adenocarcinoma and possible therapeutic strategi...
Hangyu Fang,Xiaoe Li,Shuping Wang et al.
Hangyu Fang et al.
[This corrects the article DOI: 10.3389/fgene.2025.1536331.]. Keywords: m.3243A>G; mitochondrial diabetes me...
Published Erratum
Frontiers in genetics. 2025 Jul 8:16:1645252. DOI:10.3389/fgene.2025.1645252 2025
Integrating genome and transcriptome analysis to decipher balanced structural variants in unsolved cases of neurodevelopmental disorders [0.03%]
整合基因组和转录组分析以解码神经发育障碍未解病例中的平衡结构变异
Simona Mellone,Alice Spano,Denise Vurchio et al.
Simona Mellone et al.
Introduction: Balanced chromosomal abnormalities (BCAs) are structural variations that can underlie a wide spectrum of neurodevelopmental disorders, often remaining undetected by conventional diagnostic approaches. Whole-...
Identification and validation of DNA methylation-driven gene OSR1 as a novel tumor suppressor for the diagnosis and prognosis of breast cancer [0.03%]
鉴定和验证DNA甲基化驱动基因OSR1作为乳腺癌诊断和预后的新抑癌基因及其作用机制研究
Jian Xu,Biao Yang,Ling Cheng et al.
Jian Xu et al.
Introduction: Aberrant DNA methylation plays a critical role in the initiation and progression of cancer, yet its association with breast cancer remains inadequately defined. This study aims to clarify the link between me...
A novel vasculogenic mimicry-related nomogram predicts prognosis in hepatocellular carcinoma [0.03%]
一种新颖的血管生成模仿相关预后预测模型用于肝细胞癌
Yun Zhong,Fadian Ding,Han Zhang et al.
Yun Zhong et al.
Objective: Hepatocellular carcinoma (HCC) is the most common type of liver cancer and has a poor prognosis. Vasculogenic mimicry (VM) is an angiogenic process associated with the growth and spread of malignant tumors. In ...
Geometry-enhanced graph neural networks accelerate circRNA therapeutic target discovery [0.03%]
几何增强的图神经网络加速circRNA治疗靶点发现
Zhen Li,Mingming Qi,Juyuan Huang et al.
Zhen Li et al.
Circular RNAs (circRNAs) play pivotal roles in various biological processes and disease progression, particularly in modulating drug responses and resistance mechanisms. Accurate prediction of circRNA-drug associations (CDAs) is essential f...
Identification of a novel microdeletion at 9q21.13 in a family with epilepsy, intellectual disability, and speech disorders and literature review [0.03%]
9q21.13区微缺失的鉴定及其在癫痫、智力障碍和言语障碍家系中的作用及文献复习
Liqing Jiang,Jiaqi Li,Aizhong Han et al.
Liqing Jiang et al.
Background: At present, there are few reports on 9q21.13 microdeletion syndrome, which is characterized by intellectual disability, epilepsy, autistic behaviour, and recognizable facial features, etc. The aim of this stud...