Development and validation of a machine-learning-based model for identification of genes associated with sepsis-associated acute kidney injury [0.03%]
开发和验证用于识别与脓毒症相关急性肾损伤相关的基因的机器学习模型
Chen Lin,Meng Zheng,Wensi Wu et al.
Chen Lin et al.
Background: Sepsis frequently induces acute kidney injury (AKI), and the complex interplay between these two conditions worsens prognosis, prolongs hospitalization, and increases mortality. Despite therapeutic options suc...
FilaggrinHigh melanomas exhibit active FGFR and allergic signatures with impaired GNA14 and Th1 signatures [0.03%]
富含FLG的黑色素瘤表现出活跃的FGFR和过敏特征以及受损的GNA14和Th1特征
Goodwin G Jinesh,Isha Godwin
Goodwin G Jinesh
Filaggrin gene (FLG/FLG2) product deregulations are associated with various allergic skin diseases, including but not limited to atopic dermatitis, alopecia areata, and ichthyosis vulgaris. However, the molecular immunological underpinnings...
Case Report: Pediatric CNS-isolated hemophagocytic lymphohistiocytosis secondary to uniparental disomy of PRF1 mutation [0.03%]
个例报道：PRF1基因单亲型二体性所致儿童中枢神经系统隔离型噬血细胞综合征
Jiao Xue,Zhenfeng Song,Hongshan Zhao et al.
Jiao Xue et al.
Background: Central nervous system-isolated hemophagocytic lymphohistiocytosis (CNS-HLH) is a rare disease caused by mutations in several genes. Methods: ...
Estimation of breed composition of South African sheep affected with wet carcass syndrome [0.03%]
受湿尸综合征影响的南非绵羊品种构成估算
Bhaveni B Kooverjee,Magrieta A Van Der Nest,Michael D MacNeil et al.
Bhaveni B Kooverjee et al.
Wet carcass syndrome (WCS), a condition that negatively affects the quality of carcasses after slaughter, is seriously threatening the South African sheep industry. Despite its economic impact, the underlying genetic mechanisms of WCS remai...
Ultrasound combined with molecular genetics to diagnose hereditary Renpenning syndrome in early pregnancy: a case report [0.03%]
产前超声联合分子遗传诊断赖彭宁氏症候群一例报告
Yongmei Shen,Lei Zhang,Yaqi Li et al.
Yongmei Shen et al.
Renpenning syndrome is a rare X-linked genetic disorder caused by variants in the PQBP1 gene, but the information about its prenatal presentation is very limited. A 35-year-old woman experienced two male pregnancies with thickened nuchal tr...
Preliminary investigation of the effect of ferulic acid on miRNAs and LncRNAs in Mongolian horse skeletal muscle satellite cells [0.03%]
伞形花内酯对蒙古马骨骼肌卫星细胞miRNA和LncRNA的影响的初步研究
Wendian Gong,Wenqi Ding,Tugeqin Bou et al.
Wendian Gong et al.
Introduction: Ferulic acid (FA), a natural antioxidant, has attracted considerable attention for its regulatory potential in skeletal muscle development, energy metabolism, and muscle fiber type transformation. ...
Identification of biomarkers between coronary artery disease and non-alcoholic steatohepatitis: a combination of bioinformatics and machine learning [0.03%]
冠心病和非酒精性脂肪肝疾病间生物标志物的识别：基于生物信息学和机器学习的方法
Yihong Lin,Jingmei Song,Xiaohong Li
Yihong Lin
Background: Non-alcoholic steatohepatitis (NASH) commonly complicates coronary artery disease (CAD), yet the interaction mechanism remains unclear. Our research seeks to investigate the common mechanisms and key signature...
Incorporating graph representation and mutual attention mechanism for MiRNA-MRNA interaction prediction [0.03%]
结合图表示和相互注意机制的MiRNA-mRNA互作预测模型
Tai-Long Shi,Lei Wang,Leon Wong et al.
Tai-Long Shi et al.
Introduction: Predicting interactions between microRNAs (miRNAs) and messenger RNAs (mRNAs) is crucial for understanding gene expression regulation mechanisms and their roles in diseases. Existing prediction methods face ...
Exploring the prognostic significance and therapeutic potential of SUCLG2 in prostate cancer [0.03%]
SUCLG2在前列腺癌预后价值和治疗潜能的探究
Bao Hua,Qing Yang,Shangqing Song et al.
Bao Hua et al.
Background: Prostate cancer (PCa), a highly heterogeneous cancer with a complex molecular pathogenesis, is a leading cause of cancer-related mortality among men globally. The present study presents a lipid metabolism-base...
Case Report: A rare chromosomal imbalance with dup 7q36.3-qter and del 7pter-p22.3 arising from parental pericentric inversion [0.03%]
案例报告：来自父母臂间倒位的7q36.3-qter重复和7pter-p22.3缺失导致的罕见染色体不平衡
Rongbo Lin,Wenhui Zhang,Mingwei Huang et al.
Rongbo Lin et al.
Chromosomal abnormality is a significant cause of neurodevelopmental delay and congenital malformation. Only a few cases of chromosome 7 imbalances with both duplication of the distal long arm (7q) and deletion of the distal short arm (7p) ...