Neutrophils and aortic medial amyloid: mutually beneficial or a dangerous combination? [0.03%]
中性粒细胞和主动脉中膜淀粉样变：互利共生还是危险组合？
Alana Maerivoet,Sarah Shirley,Rebecca Price et al.
Alana Maerivoet et al.
Introduction: Amyloid deposition and inflammation are associated with many human diseases, with inflammatory cells found co-localised with amyloid in a range of tissues. Medin is the peptide that forms the most common loc...
High PVR protein expression marks clear cell renal cell carcinoma with metastatic spread [0.03%]
PVR蛋白高表达预示肾透明细胞癌的转移性发展
Paola Kučan Brlić,Ema Bellulovich,Mijo Golemac et al.
Paola Kučan Brlić et al.
Background: The poliovirus receptor (PVR) is an emerging therapeutic target currently under clinical investigation in combination with checkpoint inhibitors. Although it is broadly expressed across many malignancies, its ...
High throughput profiling of the B cell repertoire identifies systematic changes in the repertoire of individuals with Crohn's disease [0.03%]
高通量B细胞受体文库测序在克罗恩病中的应用表明克罗恩病人免疫谱系发生系统性改变
Aya K H Mahdy,Zahra Taheri,Marte Lie Høivik et al.
Aya K H Mahdy et al.
The B cell repertoire contains the recombined sequences that encode the entire antibody repertoire of an individual. The repertoire is made from three antigenic binding chains, namely the immunoglobulin heavy chain (IGH) and two immunoglobu...
Correction: Unlocking the adenosine receptor mechanism of the tumour immune microenvironment [0.03%]
Correction: 肿瘤免疫微环境中山脉素受体的作用机制
Yecheng Han,Chenshuang Dong,Mingwang Hu et al.
Yecheng Han et al.
[This corrects the article DOI: 10.3389/fimmu.2024.1434118.]. Keywords: adenosine receptor; immunotherapy; s...
Published Erratum
Frontiers in immunology. 2026 Feb 5:17:1786407. DOI:10.3389/fimmu.2026.1786407 2026
Immune activation and microenvironmental crosstalk in hairy cell leukemia [0.03%]
毛细胞白血病中的免疫激活和微环境交叉信号通路
Hammad Tanzeem,Eric J Vick
Hammad Tanzeem
Hairy cell leukemia (HCL) is an indolent leukemic B-cell malignancy that typically presents with pancytopenia and splenomegaly. Many patients achieve durable initial remissions with nucleoside analogs but ultimately relapse as leukemic cell...
Clinical outcomes and safety of continuous immunotherapy beyond progression in patients with extensive-stage small cell lung cancer: a retrospective real-world study [0.03%]
广泛期小细胞肺癌患者病情进展后继续接受连续免疫治疗的临床疗效和安全性：一项真实世界回顾性研究
Chengjun Wang,Tiantian Xuan,Yanan Wang et al.
Chengjun Wang et al.
Background: Immunochemotherapy has been approved as first-line treatment for extensive-stage small cell lung cancer. However, second-line treatment options and whether continuous immunotherapy will improve clinical outcom...
Multicenter Study
Frontiers in immunology. 2026 Feb 6:16:1681545. DOI:10.3389/fimmu.2025.1681545 2026
Case Report: Telitacicept in the treatment of cSLE-APS: novel therapeutic perspectives on autoimmune thrombotic diseases in children [0.03%]
案例报告：telitacicept在儿童cSLE-APS治疗中的新治疗前景(autoimmune thrombotic疾病的治疗)
Jingyue Liu,Zhilang Cao,Yajun Wang et al.
Jingyue Liu et al.
Thrombotic antiphospholipid syndrome (APS) in Childhood-onset systemic lupus erythematosus (cSLE) remains a therapeutic frontier. Here, we report the first case of telitacicept (a TACI-Fc fusion protein)- induced remission in cSLE related a...
Emerging novel methodologies to understand and strategically target long-lived plasma cells in vaccine design to induce durable immunity [0.03%]
理解并有效诱导长寿浆细胞的新型疫苗设计策略
Gina Cusimano,Ryan P Staupe,Nicole L Sullivan
Gina Cusimano
Long-lived plasma cells (LLPCs) are a subset of antibody secreting cells (ASCs) that reside within lymphoid tissues, including the bone marrow (BM) and gut associated lymphoid tissues (GALT), and can secrete antigen-specific antibodies for ...
Enhancing Named Entity Recognition for immunology and immune-mediated disorders [0.03%]
增强免疫学和免疫介导性疾病命名实体识别技术
Songyue Chen,Jinshan Che,Mingming Sun et al.
Songyue Chen et al.
Introduction: Named Entity Recognition (NER) in the biomedical domain, particularly within immunology and immune-mediated disorders, presents unique challenges due to the presence of complex, nested, and overlapping entit...
Yinhua Gouteng decoction alleviates tic disorder symptoms by modulating neuro-inflammation in a rat model [0.03%]
银花钩藤饮通过调节神经炎症缓解抽动障碍症状的机制研究小鼠模型中的作用和机制研究
Mingge Hu,Yan Yang,Shuxia Wang et al.
Mingge Hu et al.
Background: Tic disorders (TDs) are childhood-onset neurodevelopmental disorders characterized by complex neurochemical dysregulation, and inflammation plays a critical role in TD pathogenesis. Yinhua Gouteng Decoction (Y...