Melissa officinalis extract selectively suppresses STAT1 signaling in oral epithelial cells [0.03%]
Melissa officinalis提取物选择性抑制口腔上皮细胞中的STAT1信号传导
Issam Rasheed,Layla Panahipour,Ronald A Glabonjat et al.
Issam Rasheed et al.
Oral inflammatory diseases such as oral lichen planus are characterized by dysregulated chemokine production and persistent interferon-associated signaling, with JAK/STAT pathways playing a central role in epithelial-immune crosstalk. Here,...
Retraction: ILC2s improve glucose metabolism through the control of saturated fatty acid absorption within visceral fat [0.03%]
撤稿：ILC2通过控制内脏脂肪中的饱和脂肪酸吸收来改善葡萄糖代谢
Frontiers Editorial Office
Frontiers Editorial Office
[This retracts the article DOI: 10.3389/fimmu.2021.669629.]. Copyright © 2026 Frontiers Editorial Office.
Characterization of cancer-associated fibroblast populations that promote tertiary lymphoid structure formation in murine melanoma tumors [0.03%]
小鼠黑色素瘤肿瘤中促进三级淋巴结构形成的癌相关成纤维母细胞群体的特征分析
Robert Barnes,Kara Cummings,Mirna Perusina Lanfranca et al.
Robert Barnes et al.
Introduction: In recent years, the clinical relevance of tertiary lymphoid structures (TLS) in cancer has become increasingly clear. However, the mechanisms that promote TLS development have remained obscure, largely beca...
CCL25 chemokine promotes antiviral tissue resident CD4+ and CD8+ effector memory TRM cells associated with a reduction of ocular herpes infection and disease: a potential gut-eye axis in herpes immunity [0.03%]
CCL25趋化因子促进抗病毒组织驻留记忆T细胞相关的眼部疱疹感染和疾病减少：肠道-眼睛轴在疱疹免疫中的潜在作用
Azizur Rahman,Swayam Prakash,Sweta Karan et al.
Azizur Rahman et al.
CCL25, a mucosal chemokine mainly produced in the gut, is known for its role in intestinal immunity through CCR9. In this study, we tested whether CCL25 also contributes to ocular immunity within the gut-eye axis during herpes simplex virus...
CXCL10 rs8878 identifies a genotype-associated immune phenotype linked to T-lymphocyte preservation and survival in sepsis [0.03%]
CXCL10rs8878位点的基因型与脓毒症中T淋巴细胞保存和生存相关的免疫表型相关
Birte Dyck,Andrea Witowski,Thilo Bracht et al.
Birte Dyck et al.
Background: Sepsis is characterized by a dysregulated host response to infection, leading to concurrent hyperinflammation and immunosuppression, including profound alterations in T lymphocyte homeostasis. The chemokine CX...
Immune-inflammatory endotypes of chronic rhinosinusitis: from epithelial alarmins to personalized therapy [0.03%]
慢性鼻窦炎的免疫炎症亚型：从上皮报警素到个性化治疗
Hanxiong Li,Longting Wang,Dingbo Li
Hanxiong Li
Chronic rhinosinusitis (CRS) is a prevalent and complex inflammatory disease within otolaryngology, traditionally classified into phenotypes based on the presence (CRSwNP) or absence (CRSsNP) of nasal polyps. However, these phenotypic class...
Reduced IgM natural autoantibody levels against heat shock proteins are associated with disease severity in juvenile idiopathic arthritis [0.03%]
幼年特发性关节炎患者针对热休克蛋白的IgM天然自身抗体水平降低与疾病严重程度相关
Bernadett Mosdósi,Vivien Mátis,Ádám Győri et al.
Bernadett Mosdósi et al.
Introduction: Natural autoantibodies (nAAbs) contribute to immune homeostasis and may be altered in patients with autoimmune diseases. While anti-heat shock protein (Hsp) antibodies have been previously described in juven...
Fetal sex shapes maternal immune adaptation: placental extracellular vesicles differentially reprogram the phenotype, metabolism, and function of circulating monocytes [0.03%]
胎儿性别塑造母体免疫适应：胎盘细胞外囊泡通过不同的方式重新编程循环单核细胞的表型、代谢和功能
Julieta Avalos,Florencia Sabbione,Daiana Rios et al.
Julieta Avalos et al.
Introduction: Maternal immune adaptation during pregnancy is orchestrated by dynamic signals from the uterine microenvironment, including placental extracellular vesicles (pEVs) released into maternal circulation. EVs hav...
Spatial transcriptomics reveals an SPP1-centered immune-fibrotic axis associated with fibrosis-related tissue remodeling in IgG4-related disease [0.03%]
空间转录组学揭示了IgG4相关疾病纤维化相关的组织重塑中以SPP1为中心的免疫-纤维化轴
Motohisa Yamamoto,Ryuta Kamekura,Masaaki Uehara et al.
Motohisa Yamamoto et al.
IgG4-related disease (IgG4-RD) is a fibroinflammatory condition characterized by progressive organ damage; however, the spatial organization linking immune dysregulation to fibrotic remodeling remains incompletely understood. In this study,...
B7-H3 (CD276): an actionable therapeutic target and prognostic biomarker across human malignancies [0.03%]
B7-H3(CD276)：人类恶性肿瘤中的可治疗性靶点及预后生物标志物
Dayna Smith,Anudishi Tyagi,Venkata Lokesh Battula
Dayna Smith
Immune checkpoint protein B7-H3 (CD276) has garnered increasing attention as a cancer immunotherapy target. Despite the absence of a definitively identified receptor, B7-H3 is implicated in multiple mechanisms of tumor progression. As a can...