Impact of prior solid tumor on outcomes of hematopoietic stem cell transplantation for hematologic malignancies: a propensity score-matched study [0.03%]
造血细胞恶性肿瘤患者的造血干细胞移植结果受前期实体瘤的影响：倾向性匹配研究
Jieya Luo,Mingyang Wang,Yunxia Zhou et al.
Jieya Luo et al.
Background: The Hematopoietic Cell Transplantation-Specific Comorbidity Index (HCT-CI) assigns a high-risk score to patients who develop secondary hematologic malignancies following solid tumors, indicating an increased r...
Tachykinin-related peptide signalling is important for the immune response of the mealworm beetle Tenebrio molitor L [0.03%]
速激肽相关肽信号传导对于粉虫(Tenebrio molitor L.)免疫反应的重要性
Natalia Konopińska,Karolina Walkowiak-Nowicka,Grzegorz Nowicki et al.
Natalia Konopińska et al.
Introduction: Insects possess a well-developed innate immune system, which encompasses both cellular and humoral mechanisms. On the basis of the similarities in neuropeptide actions between insects and vertebrates, we ass...
Recombinant ROP8 antigen: diagnostics, immunogenicity, and therapeutic targeting in toxoplasmosis [0.03%]
重组ROP8抗原：托拉菌病的诊断、免疫原性及靶向治疗
Maciej Chyb,Adrian Bekier,Malwina Kawka et al.
Maciej Chyb et al.
Introduction: Toxoplasma gondii invasion relies on the battery of specialized proteins, such as ROP8, which plays a key role in formation of parasitophorous vacuoles within host cells. The aim of the work was to evaluate ...
Impact of immune-related adverse events on treatment outcomes in advanced esophageal squamous cell carcinoma treated with immune checkpoint inhibitors [0.03%]
免疫检查点抑制剂治疗晚期食管鳞癌疗效与免疫相关不良事件的关系分析
Tianhang Zhang,Xiao Chen,Jianhua Wu et al.
Tianhang Zhang et al.
Background: While immune-related adverse events (irAEs) are associated with better prognosis in advanced esophageal squamous cell carcinoma (ESCC), the prognostic impact of single-organ irAE (uni-irAE), multiple-organ irA...
Systemic immune dysregulation in hypertensive disorders of pregnancy persists years after delivery [0.03%]
妊娠期高血压疾病的系统性免疫调节紊乱在分娩多年后仍然存在
Maximilian Sabayev,Edward A Ganio,Ina A Stelzer et al.
Maximilian Sabayev et al.
Background: Hypertensive disorders of pregnancy (HDP), including preeclampsia and gestational hypertension, are associated with an increased risk of cardiovascular disease (CVD) later in life. Mechanisms that link HDP to ...
Utility of contrast-enhanced ultrasound for assessing disease activity in takayasu arteritis with carotid artery involvement: a scoping review [0.03%]
造影增强超声在主动脉弓综合征伴颈动脉受累时评估疾病活动度的价值：系统综述
Carina Soto-Fajardo,Rosa-Elena Cervantes-Ramírez,Carlos-Vidal Montiel-Castañeda et al.
Carina Soto-Fajardo et al.
Takayasu arteritis (TA) is a chronic, immune-mediated vasculitis that primarily affects the large arteries, particularly the aorta and its main branches, leading to stenosis, occlusion, dilation, or aneurysms. Traditional imaging modalities...
Case Report: Unusual persistent elevation of troponin I-systemic sclerosis masked by acute myocardial infarction [0.03%]
个例报告：系统性硬化病所致罕见的持续性心肌损伤[肌钙蛋白I升高]——被急性心肌梗死所掩盖
Lixia Zhang,Shuqi Li,Jinglei Niu et al.
Lixia Zhang et al.
Myocardial infarction (MI) is a serious cardiovascular emergency that causes myocardial necrosis due to acute occlusion or spasm of a coronary artery leading to persistent ischemia and hypoxia; it is the major cause of death in patients wit...
Immunoglobulin G N-glycosylation remodeling in viral infections: immunomodulatory roles and potential biomarker implications [0.03%]
病毒感染中的免疫球蛋白G岩藻糖基化重构及其免疫调节作用和潜在生物标志物价值
Ruxu Yan,Chunqing Wang,Xuezhen Zhao et al.
Ruxu Yan et al.
The glycosylation of Immunoglobulin G (IgG), a complex post-translational modification, is essential for the structure and function of IgG. The varying affinities of different IgG N-glycans for Fcγ receptors can influence inflammatory resp...
Heguo Yan,Niqin Xiao,Bo Yang et al.
Heguo Yan et al.
Ferroptosis, an emerging form of iron-dependent programmed cell death, has recently gained substantial research interest due to its involvement in various inflammatory disorders. Gouty arthritis (GA), a chronic inflammatory disease driven b...
The impact of p53 mutation on tumor immune evasion: mechanistic insights and clinical implications [0.03%]
p53突变对肿瘤免疫逃逸的影响：机制和临床意义启示
Luo Liang,Weidong Wang
Luo Liang
Mutant p53(Mtp53) not only loses its canonical tumor-suppressive functions but also acquires oncogenic gain-of-function properties, positioning it as a central orchestrator in reshaping the tumor immune microenvironment. This review systema...